Conserved Protein Domain Family
Cas_Csy3
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pfam09615: Cas_Csy3 
CRISPR-associated protein (Cas_Csy3)
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.
Links
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Statistics
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PSSM-Id: 490497
Aligned: 28 rows
Threshold Bit Score: 398.948
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q5NPQ2         9 TASVLSFERKLDPSDALFFSGNWSNKsdDKAWQPIHLREKSVRGT---ISNRL----KKGEA-DPAKLNAAIEKP----- 75  Zymomonas mobilis
Q83EZ4         9 IASVLSFEKKLIPSDGYMFGTSWDKK---SEVTPLKLREKAVRGT---ISNRFnkndSKTFLdDPMKLDADVERP----- 77  Coxiella burnetii
WP_011769777   7 IASVLAFEKKLVPSDGYMYGTNWDNK---TLVTALSLIEKSVRGT---ISNRL----KAAIKsDPVKLNTEVEKA----- 71  Psychromonas in...
WP_014703620   7 TASVLAFEKKLVPSDGYMYGCQWDNK---SEAAPLSLNEKSVRGT---ISNRL----KPALQkDPAALNNEVEKP----- 71  Methylophaga fr...
WP_005371075   8 sASVLAFEKKLVPSDGRLYGTTWERR--AEQATSLKLQEKSVRGT---ISNRL----KKALQdDPAKLDAEVEKP----- 73  Methylomicrobiu...
WP_013818082   6 dATVLAFEKKLVPSDGYLYGTTWNDR---SKVKPLTLTPKSVRGT---ISNRL----KPALQnDPLKLNAEVEKP----- 70  Methylomonas me...
WP_014454509   8 MASVLAYEKKIVPSDARMYGTIWEAR--HSERKPLNIIEKSIRGT---ISNRL----STALKnDPSKIDAEVEKA----- 73  Spirochaeta afr...
WP_034617985  14 VPSVLAFNRKIEPSDALMQAGLWSNRdqVSTWKNIDLHQKRNRGT------------KSQYG----VPDAEKTDP----- 72  Acinetobacter
Q6F9L4         7 LPGSLSLQRGTVVSDGAFFNLFEDGK-----QEPLHVMYHGIRGTqnvAGNKE----KGAATgNSLAREVT--------- 68  Acinetobacter b...
Q3J7J3         6 LPSLLNYTRSIVPSEGTFWVANADNR-------PLLIQDKTLLGT---IANY-----SSVYKkDKQRDEGAIEKEmmagd 70  Nitrosococcus o...

Q5NPQ2        76 -NLQTVDVATLPFDSDTL--------KVEFTLRVLGGVGEPAACNSMEYRSKLVATISHYIDTHGLDILGNRYAANLANG 146 Zymomonas mobilis
Q83EZ4        78 -NLQRVDACALDQNQDTL--------KLCFTLKVLGGITNPSACNNALFKQSYKAAAKIYIDTHGFTELATRYAENLANA 148 Coxiella burnetii
WP_011769777  72 -NLQTIDVCALAPEQDTL--------KLHFTLKILGGVQQPSACNNALFKQSYSKAVNKYIEKEGFKELGKRYALNLANA 142 Psychromonas in...
WP_014703620  72 -NLQTVDACSLGTEQDTL--------KLHFTLKVLGGLKQPSACNNAAFKEGYQQAVSSYLETQGMRELAKRYALNIANA 142 Methylophaga fr...
WP_005371075  74 -NLQTVDSCALGSDQDTL--------KLTFTLKILSGVEKPSACNSAEFNASYAKSAKAYIDSEGFRDLALRYAANIANG 144 Methylomicrobiu...
WP_013818082  71 -NLQTVDACALAEDQDTL--------KLSFTLKVLGGIDKPSASNGPEFNKSYHGVAQNYVAETGFTELAKRYAINIANG 141 Methylomonas me...
WP_014454509  74 -NLQKVDSCGLAMEQDTL--------CIEFTLKVLSGVENPSACNNVQFLETYQIAAQDYIARENFTELGKRYAVNIANG 144 Spirochaeta afr...
WP_034617985  73 -NLVWGDDARLPFDADTL--------KVFFTVKFLGNIAEPTTHNRPEFENKLNEKFQEYSEKIGFLTLAQRYIYNLVNA 143 Acinetobacter
Q6F9L4        69 -NIQLTESAKLQPNAKLLvkwdfrfiDLSYVLFASASKAGADKTEEYNFRQAFLNFVNRAKESDGLKEVVRRYVRNIVNG 147 Acinetobacter b...
Q3J7J3        71 nNIQRVDSCHLPADADTF--------ELRFTLKFLANANGPEACEGAEFREDLESIAQAYAEKGGFTLLAERYLANLLNG 142 Nitrosococcus o...

Q5NPQ2       147 RFLWRNRLGADAISIQITRLSGDeSTLVGVF-DALAHPLRQFEEKsvSEELEALAKLITAGLAGQ-EHVLLRVKAFIRMG 224 Zymomonas mobilis
Q83EZ4       149 RFLWRNRFGAERIEVRVNASNKT-VSQKWAF-DATKFNLHTFDSS--DTSVKELGALIANALSSEdDYLLLDVNCYVQVG 224 Coxiella burnetii
WP_011769777 143 RFLWRNRVGSENIEVQVNALNKD-SKQSWGF-DATQFSMRNFDDA--NAQVLELGDRIAKALSSEdDFLMLEINCFVQLG 218 Psychromonas in...
WP_014703620 143 RFLWRNRFGAEAILVQVKALNKG-AEQSWEF-DALELNPRDMEVT--TADVESLADRIASALSSDnDFLMLDITCYAKVG 218 Methylophaga fr...
WP_005371075 145 RFLWRNRVGTEKIEVAVKVLNQG-DRSAWLF-DAKAVSTRYFDNP--DPQIAELAGKIADALSGKtEFLLLEVNAYAQVG 220 Methylomicrobiu...
WP_013818082 142 RYLWRNRVGAEKVEVVVS-LNEG---ETLSF-DAKQFSLRDFNAD--SPDLQKLAGKIAAALSGNlPYLLIRVEAYALVG 214 Methylomonas me...
WP_014454509 145 RFLWRNRFGADSVEIRVEQLGSDeHEEPMIF-NAFSYSVKSFDTD--DTDVQKLGNEIAKVLSGKvSHKLFRISAYAKVG 221 Spirochaeta afr...
WP_034617985 144 RFLWRNRLGAEKISIQIKNSETG---KIWNFeDAYQFGLNTFDSIq-DSQLMEIANLVSNSFKED-HYLLLEVTAFAKVG 218 Acinetobacter
Q6F9L4       148 RWLWRNRIVAESITIQVTAQDYP---ETFSF-DALSYNLKSFAEP--SEQEQKLAGILLKGITGEsTNAALHIEAIVDFG 221 Acinetobacter b...
Q3J7J3       143 RFLWRNRYGVQR-QITLRAPYNElKEKTFEIiDRAEPTLPQVRMD----ELKPWIDHIASALSGKtSFFLMEVSARVTIG 217 Nitrosococcus o...

Q5NPQ2       225 E-GQEVFPSQELLLDKG----KSTKSRFLYSVgqdeK----------AIAAIHSQKIGNALRTIDTWY-PDAE----ING 284 Zymomonas mobilis
Q83EZ4       225 S-SQEVYPSEELVLDKSssdkKGKKTKILYAV----N----------DIAAMHSQKIGNAIRTIDTWY-PDFTnqeqTAG 288 Coxiella burnetii
WP_011769777 219 K-AQEVYPSEELVLDKG----KGTKSKILYAV----K----------DIAAMHSQKIGNALRSIDTWY-PEFVevekTAG 278 Psychromonas in...
WP_014703620 219 K-AQDVYPSEELVLDKG----KGNKSKILYSV----D----------GMAAMHSQKLGNAMRTIDTWY-PEHDdavaSAG 278 Methylophaga fr...
WP_005371075 221 L-AQDVYPSEELVLDKGs--sKSKKSKILYEI----D----------GIAGMHSQKIGNALRTIDTWY-PGYDe--aQIG 280 Methylomicrobiu...
WP_013818082 215 S-AQEVYPSEELVLDKG----KGNKSKILYAV----N----------GTAALHSQKIGNAIRTIDTWY-PAFAe--aGIG 272 Methylomonas me...
WP_014454509 222 L-GQEVYPSEELVLDKG----KGNKGKVLFDI----N----------GVAGMHSQKIGNAIRTIDTWY-PEYAd--sTVG 279 Spirochaeta afr...
WP_034617985 219 E-GQHVFPSQEMVMDPP----KGQKSKYLYEIktkeG----------FCAGIHSEKIGNAIRTIDNWYvDETN----DLK 279 Acinetobacter
Q6F9L4       222 MgGVEVFPSQNYLEDKP----KG-FSRSLYQLtpkkPdhkandnqylGQAALRDQKIGNALRTIDTWY-PSFKe--nDEK 293 Acinetobacter b...
Q3J7J3       218 L-GQEVYPSQEFVDKDSr--gQGKKSKTLFFVqvadQ----------QVAAMHSQKIGNAIRTIDNWY-PDAN----ADR 279 Nitrosococcus o...

Q5NPQ2       285 P-IAVEPYGSVTTQGVAYRQPK-AKKDFYSLLDAW-VLKDKE---PTIE----DQHFVAAVLVRGGVFG 343 Zymomonas mobilis
Q83EZ4       289 P-IAIEPYGAVTNLGRSYRTPK-DKQDFYTFFDAW-ARGEQL---ARVE----DEHYVMAVLVRGGVFG 347 Coxiella burnetii
WP_011769777 279 P-IAIEPYGAVTNLGKAYRTPK-DKQDFYTFFDKW-ARGTEL---GRIE----DEHYVMAILVRGGVFG 337 Psychromonas ingrahamii
WP_014703620 279 P-IAIEPYGAVTNLGKAFRTPA-DKQDFYTFFDSW-ARGGEL---ARVE----DEHYVMGVLVRGGVFG 337 Methylophaga frappieri
WP_005371075 281 P-IAIEPYGAVTNLGKAYRTPK-DKADFYTLFDRF-ARGEKL----AEN----DEHYVMAVLVRGGVFG 338 Methylomicrobium album
WP_013818082 273 P-IAIEPYGSVTNLGKAFRTPK-DKADFYSLFDRF-ALGETL---ASKD----QEHYVMAVLVRGGVFG 331 Methylomonas methanica
WP_014454509 280 P-IAVEPYGAVTTLGKAFRTPK-NKSDFYTLFDNF-SRGGKL---ASIE----EEHYVMAVLVRGGVFG 338 Spirochaeta africana
WP_034617985 280 PaIAIEPYGSVPNRGRAYRINQ---TDFYTLLINW--LEDKE---ILED----DQHFIVANLIRGGVFG 336 Acinetobacter
Q6F9L4       294 P-IAIEPNGANLEGQIFYRVGK-DK---VSAFD---ILKEIDeldPSSE----KGMFLISCLIRGGVYS 350 Acinetobacter baylyi
Q3J7J3       280 P-LAVDPFTVDKRRARAVRLPDhGKSDFYSLLKNLpALKDDIehaPNAEaipgQAHYFMAVLIRGGVFS 347 Nitrosococcus oceani ATCC ...
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