8FCJ


Conserved Protein Domain Family
Cas6
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pfam09559: Cas6 (This model is not part of the current CDD release)
Cas6 Crispr
The Cas6 Crispr family of proteins averaging 140 residues are characterised by having a GhGxxxxxGhG motif, where h indicates a hydrophobic residue, at the C-terminus. The CRISPR-Cas system is possibly a mechanism of defence against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.
Links
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Statistics
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PSSM-Id: 518948
Aligned: 30 rows
Threshold Bit Score: 214.333
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8FCJ_B         13 DLTFKLRGAPIPLDNGYLTYAALSRICPPLHELKSIGIHPIAGIPTRNN----------LLELTAQSRLKIRIYHQQIPL 82  Nostoc sp. 'Pe...
jgi:Hhal_1950  44 DVAFPLRGRVLPEAYAVPLADALAPRLAPLLDPGEVGIRVTHLPTSGHGwwrt---pdqPILLPRRSRLVLRVARAHADA 120
Q0A841         19 DVTFRLEGHSLPADYAPALAEALADPLADFSRLPGFGVKVLHLPVSGNGwhrg---egqPIYLSRRVQLLLRVPRDRARA 95  Alkalilimnicol...
WP_012638740   19 DVSYRIDCRCLPLDHAHALSSAVLAALPWMSEEPAAGVHLIHGAESGNGwyrpqdpehdLLHLSRRARFRLRVPRTRLED 98  Thioalkalivibr...
1_pfamImport    2 DVLFALDCRSIPVDHAFALSQALLDPAPWLSEP-GCAIHLIHGAGSQNGwerpehgigrQLHLSRRTKLCIRVPKSRIAS 80 
WP_043108406   20 DLAFSIQCRELPVDHLYALGSALCEAAPVLTEDPRVAIHEIHLAGSQNGwerpdpqmgqKLVLSRRTKLHIRAPKELRER 99  endosymbiont o...
WP_014777098   20 DVLFAIDCKRLPVDHAHLLSTALQAALPWIAEEPGMALHTIHVAGSQNGwerpahgtdsELMLSRRTKLTIRAPRARVDD 99  Thiocystis vio...
WP_015279164   20 DVQFAIDAKRIPVDHGCALGEAVLAALPWEEGQAALGVHTIHVAGSQNGwqrpdhgqdqFLILSRRTKLTIRVPKSRADA 99  Thioflavicoccu...
WP_012970461   20 DLLFAIDCKRLPVDHAYALSSAVRALVPWFDEEPRLGVHTIHVAGSQNGwerpehspeaLIMVSRRTKLTIRVPSARADD 99  Allochromatium...
WP_005223278   20 ELVFAIDCRALPVDHADALHRALIVAQPWLAETAGLGIHSIHGAGSQNGwerpphgtdtCLQLSRRTKLRLRVPQHLSDS 99  Marichromatium...

8FCJ_B         83 IYPyLAGQAFHIGQNFYQLDIPDYKPLISSESVYSRLVIIK------GFQDSTNFIEAVQRQMDNLGIQGKIELLTRqdg 156 Nostoc sp. 'Pe...
jgi:Hhal_1950 121 VAG-LAGAGLDVAGEALELGGSRLSELPAAPTVYAHRVLGPd----gGAVAESALLAAARQELAEMDIHPKRLLCGR--- 192
Q0A841         96 ALA-LSGTAFEVDGEACRLARGRVRELQQVETLYASRVVPLv----hPEEDEAEFMEAVARRLAAMGVKPRKMLCGR--- 167 Alkalilimnicol...
WP_012638740   99 ARA-LVGQALRLEGHELLIGEAGVLPLQPLPALMARYVVST------PDEAEADFLARAAGALRELGVPVTKLLCGR--- 168 Thioalkalivibr...
1_pfamImport   81 LKNaLEGEVIKVAGSALRIGAGKQRLLSREGTLLARYVAHP------AGLNENGFLSWAVEELAGSGIRVRKAIGGK--- 151
WP_043108406  100 IEQaLDGLTIEIDGHPMTIGKARVKTLSRQGTLFARHIVLEp----gEEDDENTFLMRLAKLLQARGIRVKKALCDT--- 172 endosymbiont o...
WP_014777098  100 ILTqLPGTRLELDGHPLTVGVGKIKPLCKDATLFSRYVVTGn-----EDQDEQVFLEIAVRALSGMGIQVRKALCGK--- 171 Thiocystis vio...
WP_015279164  100 LKTaLTGRVLDVAGCRLTVGAGKERPLSKETTLFARYVVDP------HRRNEAQFLDWAAAELHAMDIRIRKALCGK--- 170 Thioflavicoccu...
WP_012970461  100 LAArLQGRRIDVGGQPLTIGAAKPKPLSQETTIFARYLATDpsadaeAFADESRFLEAAAQALGALDIRVRKALCGK--- 176 Allochromatium...
WP_005223278  100 LLAtLPGSHIEVAGHPLTIGQGRIRSLDPNPTQFARHVVCS------AEEDENAFLERAAETLARIEVGVRKALCGR--- 170 Marichromatium...

8FCJ_B        157 tpqRRQLTInkegKQFKVRGFGVKISELNPEDSLTLQEQGIGGKRKMMCGIFVPATR 213 Nostoc sp. 'Peltigera membranacea cya...
jgi:Hhal_1950 193 ---QETLVT----PDGPAVTRSLLVDGMGPEAGRRLQARGLGSGRCWGCGLFLPHKA 242
Q0A841        168 ---RQTLQT----RWGPVTLRSLMVAEMGPEGSYRLQSRGLGDGGLWGCGLFMPHKS 217 Alkalilimnicola ehrlichii MLHE-1
WP_012638740  169 ---EHVLRT----PDGEVHTRSLMVADLDPHGSVELQRQGLGPMRLMGCGLFIGHKD 218 Thioalkalivibrio sulfidiphilus
1_pfamImport  152 ---STPLST----PDGPLETRSLLLADLAPDESILLQQRGLGPHHEMGCGIFLPHKG 201
WP_043108406  173 ---TQKIAT----PEGPLTTRSLLLADLRPEDSIALQQDGLGSHRHFGCGIFLPHKG 222 endosymbiont of unidentified scaly sn...
WP_014777098  172 ---TTALAT----PDGPLQTRSLMLASLTAEESIRLQQTGLGTHRLMGCGIFIPHKG 221 Thiocystis violascens
WP_015279164  171 ---AVTLAT----PDGPLLTRSLLLANLDVEDSVRLQRLGLGPQRGIGCGLFIPHKG 220 Thioflavicoccus mobilis
WP_012970461  177 ---ATTLHT----PAGPIPTRALMLAGLTREESMRLQREGLGPHRALGCGLFIPHKG 226 Allochromatium vinosum
WP_005223278  171 ---ALTLVT----ADGPLHTRSLLLANLPPDESIRLQQHGLGSHRHLGCGLFIAHKG 220 Marichromatium purpuratum
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