Conserved Protein Domain Family
SSXRD
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pfam09514: SSXRD (490430 is an unknown moldel)
SSXRD motif
SSX1 can repress transcription, and this has been attributed to a putative Kruppel associated box (KRAB) repression domain at the N-terminus. However, from the analysis of these deletion constructs further repression activity was found at the C-terminus of SSX1. Which has been called the SSXRD (SSX Repression Domain). The potent repression exerted by full-length SSX1 appears to localize to this region.
Links
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Statistics
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PSSM-Id: 490430
Aligned: 12 rows
Threshold Bit Score: 26.9795
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EHB09429     163 ERKRKVSVWSKQLREWKnLMVYEEISDPEEED 194
Q96EQ9       171 LRKKNVEVKMYRLRERK-GLAYEEVSEPQDDD 201 house mouse
4_pfamImport   1 EKKKGKSVWAHRLRERKnFIIYEEISDPEEED 32 
1_pfamImport   1 TGGIQVNVWSHRLRERKyRVIYEEISDPEEEE 32 
5_pfamImport   1 SERKKVDVWANRLRKRQ-PVAYEEISDSEEES 31 
XP_042098267 175 LGRKETDMKRYSLRERK-GHVYQEVSEPQDDD 205
Q9NQW5       171 LRRKETEGKMYSLRERK-GHAYKEISEPQDDD 201 human
2_pfamImport   1 LRRKNIEVKMYSFRKRK-SQAYKECSEPQDDD 31 
ELW61807     190 VRRKETKVKMYSLRERK-CGTYKEVHEPQDDD 220
XP_016277715 167 CRRKDVEVHIYSLRERK-YQVYQEMWDPQDDD 197
3_pfamImport   1 LRRKEIEARSYNLRERT-DRSYEEVSEPQNDD 31 
ELK10079      98 LRRKGVEVKMYSLRERT-GRVYQEVSEPQDDD 128
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