Conserved Protein Domain Family
DUF2389

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pfam09493: DUF2389 
Tryptophan-rich protein (DUF2389)
Members of this family are small hypothetical proteins of 60 to 100 residues from Cyanobacteria and some Proteobacteria. Prochlorococcus marinus strains have two members, other species one only. Interestingly, of the eight most conserved residues, four are aromatic and three are invariant tryptophans. It appears all species that encode this protein can synthesize tryptophan de novo.
Statistics
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PSSM-Id: 401445
View PSSM: pfam09493
Aligned: 58 rows
Threshold Bit Score: 49.2054
Threshold Setting Gi: 147849927
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:MICPUN_60610 147 TNWTAHRRTK-GWRHFECIGkspadKANGKPRASVHLAATCDRDvTVWVDVKELKDRHLWSAGWK 210 Micromonas commoda
WP_011903192      12 TKWTAVKPIA-KQKHFLVSKvi-lpEPPNEKIEWVEIEAVFTKQ-VTQIAWRELTDSSLWLQGWK 73  Polynucleobacter asymbioticus
jgi:CAP2UW1_3147  34 SKWTAATPHD-KEKHFIVTGvi-qpEPPATRIESIELEAVYSRR-VVSLPWRHLTDRKHWLQGWQ 95  Candidatus Accumulibacter ...
WP_013819905      13 SKWTAVAPRN-KEKHFIVTKll-lpENPPTPLEFIELEAVYSKR-VHVLPWRALNDTAAWRPGWh 74  Methylomonas methanica
WP_008952891      13 SKWTALAPQN-KEKHFIVVRvl-epEHPDAPITEVELEAVYSRR-SRIIPWKTLTDATQWRQGWh 74  Pseudogulbenkiania
tigr:AHA_1107     12 SKWTKESRHElTERFYLVVAcq-rdA--QGQLQQVVMQDINTLL-EQEMDWHELEDPAHWHMGWN 72  Aeromonas hydrophila subsp...
WP_013344985      12 SKWTSNAHFH-DETHFVVTGtl-tdS--QGEVTKVVLQGVHNGR-EFELARESLEDSDLWRMGWR 71  Ferrimonas balearica
Q489J2            12 SKWTKMSVDN-QEKHFVITKvi-fdD--KQRVIECVIEAVISHN-EYPINWRDLKNSLHWKIGWQ 71  Colwellia psychrerythraea 34H
ABM03662          22 SKWTKITVLN-KEKHFLVSEve-fnE--DKKIIRCVMQAVINHA-EYEINWRSLKEGKEWLIGWK 81  Psychromonas ingrahamii 37
Q3IJ87            12 SKWTAVPAIN-KEKHFIIIEve-ydE--DSNVIACVTEAIISKS-QYPISWRDLKNAQNWLQGWK 71  Pseudoalteromonas haloplan...
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