Conserved Protein Domain Family
Dot_icm_IcmQ

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pfam09475: Dot_icm_IcmQ (This model is not part of the current CDD release)
Dot/Icm secretion system protein (dot_icm_IcmQ)
Proteins in this entry are the IcmQ component of Dot/Icm secretion systems, as found in the obligate intracellular pathogens Legionella pneumophila and Coxiella burnetii. While this system resembles type IV secretion systems and has been called a form of type IV, the literature now seems to favour calling this the Dot/Icm system. This protein was shown to be essential for translocation.
Statistics
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PSSM-Id: 490401
Aligned: 3 rows
Threshold Bit Score: 256.089
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5ZYC8        21 ILKALNDAIEKGPWDKSNFLRVIGKKLIAIRDRFLKRigaasqaKLKAESHLANRI----ALRSGQQEIYVSLYSSDGSN 96  Legionella pneu...
Q83B79        58 IIQATGQVLSAANWEESLFLRNTLKPIKKLYEEALAL-------KEKLDGEQAGQAfttpALTENKVKLYVSLYQSNGHD 130 Coxiella burnetii
WP_025386322  13 ILKALDDAIEQGPWEESNFLRVIGKNLREIREHFASQvqtsgqgKEKIASHLANRI----ALRSGQREIFVALYSSSGSS 88  Legionella oakr...
Q5ZYC8        97 LQSWEKIVGSLPRQMISRPIYADEEDIKAILKTKENKQNEAYVAIYISQSDILHlSADKAPVDKLGKPLLTLKDKSISLE 176 Legionella pneu...
Q83B79       131 LKQWALQLASLESYMVGRPIYQNEADAMQAIRQKLSQLSEACVVVAVDQSKIIS-QENRSRKDRLGNLLTTVMPNAIKSE 209 Coxiella burnetii
WP_025386322  89 LSSWERIITNLPGQMISRPIYANEKDVKEIIGTKENKVNEGYVSIYVSQTDILPtSPEKTPTDKLGKPLLTLKDRALKLE 168 Legionella oakr...
Q5ZYC8       177 NISRFVHVSGVYRYSNgrliKN 198 Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Q83B79       210 NIIEFIHQGKRYHYVN----QA 227 Coxiella burnetii
WP_025386322 169 NLNRFIHMTGTYKYVGgrlvKi 190 Legionella oakridgensis
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