2GZD


Conserved Protein Domain Family
RBD-FIP

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pfam09457: RBD-FIP 
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FIP domain
The FIP domain is the Rab11-binding domain (RBD) at the C-terminus of a family of Rab11-interacting proteins (FIPs). The Rab proteins constitute the largest family of small GTPases (>60 members in mammals). Among them Rab11 is a well characterized regulator of endocytic and recycling pathways. Rab11 associates with a broad range of post-Golgi organelles, including recycling endosomes.
Statistics
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PSSM-Id: 401421
View PSSM: pfam09457
Aligned: 10 rows
Threshold Bit Score: 51.5651
Threshold Setting Gi: 51827892
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2GZD_C     47 TYEEVLQELVKHKELLRRkdthireLEDYIDNLLVRVXEETPSILRVP 94   human
O75154    716 SRDELMEAIQKQEEINFR-------LQDYIDRIIVAIMETNPSILEVK 756  human
Q3LGD4    580 SRDELVDALKEQEEINFR-------LRQYMDKIILAILDHNPSILEIK 620  zebrafish
Q8IUD2   1068 TRGQLQDELEKGERDNAE-------LQEFANAILQQIADHCPDILEQV 1108 human
Q174W5    463 SLTQLQIAFQDKEEENRR-------LKHYIETILLQVVEHYPQLLEVK 503  yellow fever mosquito
Q9VUD7    457 SQAQLQQAFQEKEDENVR-------LKHYIDTILLNIVENYPQLLEVK 497  fruit fly
EDO38035  547 NKDTVIDALRDQEEEARR-------LRGYLDSLLMIIMEHNPSLLEIT 587  starlet sea anemone
Q9VWS3    758 SREELMLIANGMENEALLqrqrvkeLEDYLDNLLLRVMETHPKILQNP 805  fruit fly
Q9D620    588 THDELIQLVLKQKETISKkefqvreLEDYIDNLLVRVMEETPNILRVP 635  house mouse
Q7QER7    543 SREEVIKIAHTLETEVHYqkqkvkeLEDYLDSLLLKVMECHPKILQNP 590  Anopheles gambiae str. PEST
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