6L3Q


Conserved Protein Domain Family
UTP15_C
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pfam09384: UTP15_C (This model is not part of the current CDD release)
UTP15 C terminal
U3 snoRNA is ubiquitous in eukaryotes and is required for nucleolar processing of pre-18S ribosomal RNA. It is a component of the ribosomal small subunit (SSU) processome. UTP15 is needed for optimal pre-ribosomal RNA transcription by RNA polymerase I, together with a subset of U3 proteins required for transcription (t-UTPs). This entry represents the C terminal of UTP15, and is found adjacent to WD40 repeats (pfam00400).
Links
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Statistics
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PSSM-Id: 518872
Aligned: 135 rows
Threshold Bit Score: 78.3427
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6L3Q_B         1 SPKLKPWQKAFrqGRyaaavddVLNTTAPSYDPVIALTLLTALRHRSALrealQGRDELSVINILRWAGKYVADPRYRSI 80  Thermochaetoide...
Q54QV4       356 KSQQHNQTLVIddTL-------GIYKSSHLDRLLRKFEHKTAFDTAVLLn---KNIDFIFKVVCELSRRDALDIVLKNRE 425 Dictyostelium d...
XP_002141602 386 NSKPDISHIKIn-AP--------KKKITQLDRLLKAYAYGKALDLALNI-----SWLHVLTVLETLSSRGALHIVFKDIS 451
A0DIJ7       360 YSKLSDYDYKVp-tI-------QNQKFSGYDKLLVSFKYKEAIVKAFKE----KKTSIILSLVEELSERGALEVALKDID 427 Paramecium tetr...
Q9N477       348 DRDMQKVDVVAk-nA-------DKLKIPKIDGMLSNFKHAAVIKLLFGGkfrsAMDTAVVSYLRVIVMRGAIHRALAGQE 419 Caenorhabditis ...
EFO84359     336 DRETQKVEVVAk-sA-------DRLKIPKIDGMLTNYKHAAVIRLLFGGkfrsSVDAAIVSYLRVIVMRGAIHRALGGQE 407
EGT35450     327 DRDDQKVEVVAk-NP-------EKLKIPKVDGMLSSFKHAAVIRLLFSGkfrsTLEAAIVSYLRIIVMRGAIHRALAGQE 398
XP_002639405 362 DRDSRKVEVVAk-nA-------DKLKIPKIDGMLSNFKHSGVIRLLFSGkfrsSVDAAVVSYLRVIVMRGAIHRALAGQE 433
Q4QBH3       391 EKTRSKEQVLQd----------K---MKEVQFQLRSYQYGKALKTALYS----RHPDVLVSTFEELVRRGALHVALNNQN 453 Leishmania major
XP_807092    340 KDKNTQDDFLG-------------AKLHDVRQQLVSYQYNRAIKTALYS----RNSDVIVSTLEELIRRGALHVAMSGQN 402

6L3Q_B        81 CVDVAFHLIDLYAEHV--GGSAELATQFQQLLAKV--------NREVEK-AEL-AIVTGGX-VESLXXSVEAQ 140 Thermochaetoides therm...
Q54QV4       426 VSELDSILQMVNKLVN--TIKYQQCGILLLEKIVE--------FYHPSIfQEN-KSIISTM-NSIKINLIKEQ 486 Dictyostelium discoide...
XP_002141602 452 KDKLLIILKMLSRSIGrcNPSHYCIITEAIQHILNesnwqklfPLNSDI-SKSiTEITDAV-KRLIHKVTLEI 522
A0DIJ7       428 DEELQMILQFILQKMS--NPKYSGSMLHVLDILVG--------ILLSSI-------LDIYNiGDIYDQVREEL 483 Paramecium tetraurelia
Q9N477       420 RSVQKNILVFLNHNLY--KAQYFSTLKEVVNAFFD--------VYALEKlDKD---VVKHV-QSLRGSLGREL 478 Caenorhabditis elegans
EFO84359     408 ISVQKNLLIFLNHHLF--KTQYFPTLREVALAYFD--------VYSSEKlDQN---VVKQV-QRLKTTLSREL 466
EGT35450     399 FGVQKNLLSFLNHQLF--KTQYFSTLREVAIAFFE--------VYGTETlHKD---LVKQV-QRLKLTLSREL 457
XP_002639405 434 TTVQKNLLIFLNHHLF--RTEYFSILKDVTIAFFD--------VYASDKlDRD---VFKQV-QRLRVTLSREL 492
Q4QBH3       454 DRTIVRVLRFATHYVE--KPQFTDTMLVVFETIFD--------IYSAYV-GKS-AFFHREI-LNAQKKIGASL 513 Leishmania major
XP_807092    403 DRTIVRILRFLVNHVD--SPQFCESMMIVMDVIFE--------IYATCA-GKS-NFLHREM-MIARRRLGSVL 462
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