3TAZ,1ZUP


Conserved Protein Domain Family
NurA

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pfam09376: NurA 
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NurA domain
This family includes NurA a nuclease exhibiting both single-stranded endonuclease activity and 5'-3' exonuclease activity on single-stranded and double-stranded DNA from the hyperthermophilic archaeon Sulfolobus acidocaldarius.
Statistics
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PSSM-Id: 401358
View PSSM: pfam09376
Aligned: 44 rows
Threshold Bit Score: 51.4185
Threshold Setting Gi: 74574928
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3TAZ_B        65 SSIYAVDGSRSVSRLSGTVIYFLSALAVGSGKQLRLSYANAIKSNYGTS------------------------------- 113 Pyrococcus furi...
WP_012256617  60 ELVLAIDGSNYEAALDDEIPSTRLGYLKVGAILFSLKDVSKLREGRFVDpfkvaalqdqnasltfvlpsanvrikgqn-- 137 Chloroflexus au...
O26643        53 RLMAFIDGGNSPI-VEGPAISVQINRVALGLFRGEQRIQPDMPARIEFFsvmkfhpedgtyrfq---------------- 115 Methanothermoba...
Q8ZZR2        50 GDVHGLDSHTAVVEFEGVSVIVATGALVGRCSAFVPGLSASWLGVRLNFkgggdllagsrlyyk---------------- 113 Pyrobaculum aer...
Q96YB9        59 EVIYAVDGSSRSL-ISAGGIISINTLAISSSTYPIIGVYPSLFGLPSLPikkpfiglassnpikgkiepfly-------- 129 Sulfurisphaera ...
Q8ZZI4        54 PVDYAVDGSLRTITTPTFRLFLAVGVAYTKLGILTIPGFRDVKHVALQSddeealrrledvaivk--------------- 118 Pyrobaculum aer...
Q97YJ7        65 KRIASIDSSSRYLRDFSVNTCLIGLSVYSNREGFIDGPFTVDIPYIGISsyreileslkiddinvry------------- 131 Saccharolobus s...
Q972U5        65 VSIASIDSSSRYLRDPSVNMVFVGLGVYSNIKGIKVGPFDIDINFMAIGtfeellkefnpesgvr--------------- 129 Sulfurisphaera ...
Q8KB75        59 DLVLAIDGSNLAAKAENGFPGAEFGYITIASVLIDLKLIGELEKKEFVEpkkfretekastiesvfpgcnvildteknak 138 Chlorobaculum t...
CAI49308      74 PTQHGLDSGTINPTTFTNGLVIDIAHAAMAAVPSELSLHRSRTVVKTVHsndrtvdcneddwsgfdrd------------ 141 Natronomonas ph...
3TAZ_B       114 -------------------------------DQIVRMQMETLENMl--------------------------gYLAYRKL 136 Pyrococcus furi...
WP_012256617 138 --svrdsfraaldeqllsektrfdpknfhtsLRSTLFFLASRRPGdlgtgtplklklhkcptcergpveledkLDPQMCP 215 Chloroflexus au...
O26643       116 -----------------lhplreeyreflpdEDNLQLELKDAERAeesdlkglp-----------rkfadwtmATGALNE 167 Methanothermoba...
Q8ZZR2       114 -----------------srflervfdadfdlEAARDEVRYHVEEA-------------------------------LARA 145 Pyrobaculum aer...
Q96YB9       130 ---------ssnsfftsvsltgepflsiqepERIETELRSILETE-------------------------------GLKI 169 Sulfurisphaera ...
Q8ZZI4       119 ---------------yrfangekffksdvpeDVVGKVVREAVEIA---------------------------------LI 150 Pyrobaculum aer...
Q97YJ7       132 -------------knvvnyyyvnepnneykiDDIADELRLEAENV------------------------------GLKRV 168 Saccharolobus s...
Q972U5       130 ----------------vknyvnkyftedyriDDIADELRLEAENV------------------------------GLKEN 163 Sulfurisphaera ...
Q8KB75       139 sslrralfeelrsntifsdgeslldtyehlfRIKREHFQERNLPRspiegve---------------eemtydFGEYTCP 203 Chlorobaculum t...
CAI49308     142 ------------gpdgdyfsrgrvlqaphvnRYEEGVVHALSLYLae-------------------------vEHALDNA 184 Natronomonas ph...
3TAZ_B       137 EGEKRAILMDGTLTGSLVrppvypedirslnvmraligesdfenllnefleklrdhyrkveehlekngnydspiltdnvv 216 Pyrococcus furi...
WP_012256617 216 YCGAPVYPSDCLRIWEEV-------------------------------------------------------------- 233 Chloroflexus au...
O26643       168 LDDGDILVRDGSLRASFE-------------------------------------------------------------- 185 Methanothermoba...
Q8ZZR2       146 WDGGGVLLLDGPVFRALDvlk----------------------------------------------------------- 166 Pyrobaculum aer...
Q96YB9       170 TKDKGLTVIDGPLFPSHIy------------------------------------------------------------- 188 Sulfurisphaera ...
Q8ZZI4       151 KEAKGTALIDGPLYYGIR-------------------------------------------------------------- 168 Pyrobaculum aer...
Q97YJ7       169 IQNHDIVIIDGPIYPTPLelteein------------------------------------------------------- 193 Saccharolobus s...
Q972U5       164 RNTHDLVIVDGPLFPTPLelselel------------------------------------------------------- 188 Sulfurisphaera ...
Q8KB75       204 HSGEPLFSTDALRLHELM-------------------------------------------------------------- 221 Chlorobaculum t...
CAI49308     185 EAVEDLLVLDGPIYPKGLlawsdrs------------------------------------------------------- 209 Natronomonas ph...
3TAZ_B       217 eklrkkyidtkviaygsgkvkvkiprkalgysprvipievlessrgksvdellqeldeekvelylgkddiydalHMTLSY 296 Pyrococcus furi...
WP_012256617 234 --------------------------------------------------------------------------TDYQSN 239 Chloroflexus au...
O26643       186 -----------------------------------------------------------------------------REK 188 Methanothermoba...
Q8ZZR2       167 -----------------------------------------------------------------------rggVYAFLY 175 Pyrobaculum aer...
Q96YB9       189 --------------------------------------------------------------------------LPEKVR 194 Sulfurisphaera ...
Q8ZZI4       169 ------------------------------------------------------------------------------GF 170 Pyrobaculum aer...
Q97YJ7       194 -------------------------------------------------------------------letearrKHRLAY 206 Saccharolobus s...
Q972U5       189 --------------------------------------------------------------------qsegrkRHQEAY 200 Sulfurisphaera ...
Q8KB75       222 --------------------------------------------------------------------------NPGGSN 227 Chlorobaculum t...
CAI49308     210 -------------------------------------------------------------------peladllVENERP 222 Natronomonas ph...
3TAZ_B       297 IEYLYSIDKLLEV-----KNLAYIAKSFYTKTLARTL------------------------------------GVEIVDT 335 Pyrococcus furi...
WP_012256617 240 QIALSRLMIVLEH-----LIPIHYIRFIEQKAFLTLTkiaffidgplaifgasaw-lhrsimiylhevntrlaKYHQPPL 313 Chloroflexus au...
O26643       189 GYIRRLGDEAMD------IHVAGLSKTCTLYTTTSMSlla-------------------------------avGRLAADC 231 Methanothermoba...
Q8ZZR2       176 SEIYKRRYELFGG-----RRVVGVVKRVDQSSYLAKCv-----------------------------------GVGSDDE 215 Pyrobaculum aer...
Q96YB9       195 EYIVKERIKVLD------EKYVGIVKRLDKSNLLVNTlkdseefi---------------------srykinpRSFLSDE 247 Sulfurisphaera ...
Q8ZZI4       171 PEIDWWRVEALWD-----KRVVAVVKRLETSKKLCRAkewvee-------------------------mgiriDAACNDM 220 Pyrobaculum aer...
Q97YJ7       207 AKLVNERIELLN------NNVIGVVKRLENSKKLWRVkeine---------------------------tignVKRMKDV 253 Saccharolobus s...
Q972U5       201 LQLTKDRISILR------NNVVGVVKRLETSQKLYKVdkvkq---------------------------llgiRYPINDA 247 Sulfurisphaera ...
Q8KB75       228 GEMFGQIMSTLEK-----LWLVHILRAFERKGWLATLrrvafimdgplavfstsswltkvisheltrlndlqrKINGQDL 302 Chlorobaculum t...
CAI49308     223 RDVVSSYLRLVEQfadrgVPLVGVVKNSASKAITRAVrne-------------------------------krAPWVNDA 271 Natronomonas ph...
3TAZ_B       336 ALLDAVIrTlighekegyleiehavVPPKWSFPDFLLSK-------------------------FRNIEKLIDKG-IHLA 389 Pyrococcus furi...
WP_012256617 314 LIIGLQK-K----------------GQIVDYLGLINRFL-------------------------PPDRLFAIDDE-YRYK 350 Chloroflexus au...
O26643       232 NMEGGWC---------------------------------------------------------YHPVAVTTDRL-TTIT 253 Methanothermoba...
Q8ZZR2       216 VAARRLLeGr---------------PGFV-----------------------------------GPVVVKWGDLA-KYMY 244 Pyrobaculum aer...
Q96YB9       248 AFLFQLV-R----------------FNYNPPYPIISVG--------------------------PLIREI-DKIR-YYVN 282 Sulfurisphaera ...
Q8ZZI4       221 AVVAELG-R----------------MHMRSYRDVVVFGPfk---------------------qtFRQSKLHPLPE-RYLW 261 Pyrobaculum aer...
Q97YJ7       254 TIIELIDeR----------------LCRKNYEYVCTIGPfkieya--------------levkdEDGRNVIEKVPtKYAY 303 Saccharolobus s...
Q972U5       248 EILNQIRiK--------------------TEFKRGLLGPf-----------------------kIEFKSKYFDAPtRYAY 284 Sulfurisphaera ...
Q8KB75       303 LIIGIEK-S----------------GTFFNHFIEIDTTKdgvt------------------dkfPKQSALLLNDG-YIKR 346 Chlorobaculum t...
CAI49308     272 AFFERVLrR-------------------TGDDGELRTDAltftnwfvsrcgvdeplskhgdalgLERNRPPEDYE-VTFC 331 Natronomonas ph...
3TAZ_B       390 YVRF------EQGDVIYMLQs-----TTNIEKILPLIL----------------------------------HHKAGGYL 424 Pyrococcus furi...
WP_012256617 351 YILAnrepsrGGFGFETYYGqdfifkTKQGRTFVFALPypypskeepgsdfirektdwtrypnlptavqlleQLQTELYR 430 Chloroflexus au...
O26643       254 AVKL------NPAGRIFRMDilgecgKDEAMEVASTLSln------------------------------arDACFPGYP 297 Methanothermoba...
Q8ZZR2       245 YVGVp----sAKGIRVLRAE-------AFDPSLAREADswl-----------------------------gsLADSSGVP 284 Pyrobaculum aer...
Q96YB9       283 YLVIpyh-kyLPKFSILRIE-------SLNKNAPAIVAs--------------------------------lPFSNDGIP 322 Sulfurisphaera ...
Q8ZZI4       262 YIY--------SASSIFRVEaf---rKEYAEEVLPTLLr---------------------------------NRVVPGLP 297 Pyrobaculum aer...
Q97YJ7       304 YVIIrk---kYFPPTFLRIEs-----TNKNLDISPVLS----------------------------------RLTERLMP 341 Saccharolobus s...
Q972U5       285 YLILtn---pIGMSSYFRIE-------SLSLDSLEELTpyi-----------------------------vnRISERLIP 325 Sulfurisphaera ...
Q8KB75       347 NIIFse--siKPYGQDTYFGrklfykAASGQKIVPVVAcfneyqrnlntanp------dqftrladvmnlldLLVSSRYP 418 Chlorobaculum t...
CAI49308     332 CVFD------PRTELLFRVEapa--vvTRDPELREALTmql----------------------------lrdIAHERGPP 375 Natronomonas ph...
3TAZ_B       425 RP---LQLAHHGVKI 436 Pyrococcus furiosus DSM 3638
WP_012256617 431 DAvipIALAHRYTAI 445 Chloroflexus aurantiacus
O26643       298 YG---LVDVDMRARV 309 Methanothermobacter thermautotrophicus str. Delta H
Q8ZZR2       285 VP---ISAADRLARR 296 Pyrobaculum aerophilum
Q96YB9       323 KI---LSIADKTAKE 334 Sulfurisphaera tokodaii
Q8ZZI4       298 YH---IALVDKLAKD 309 Pyrobaculum aerophilum
Q97YJ7       342 TY---IEIVDRRSKR 353 Saccharolobus solfataricus
Q972U5       326 TY---IEIADNLSKR 337 Sulfurisphaera tokodaii
Q8KB75       419 NSvspLVSAHAEAAI 433 Chlorobaculum tepidum
CAI49308     376 LA---VAKADELARI 387 Natronomonas pharaonis DSM 2160
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