6DC6,4NNJ


Conserved Protein Domain Family
E1_UFD

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pfam09358: E1_UFD 
Ubiquitin fold domain
The ubiquitin fold domain is found at the C-terminus of ubiquitin-activating E1 family enzymes. This domain binds to E2 enzymes.
Statistics
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PSSM-Id: 401342
View PSSM: pfam09358
Aligned: 155 rows
Threshold Bit Score: 57.1342
Threshold Setting Gi: 121968600
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6DC6_A                         912 WDRFEV--QGlqpngeEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKER---LDQPMTEIVSRVSKRKLGR 986 
EEA05978                       985 WDKIVI--Sy-----pNGTIEDIINYLRKTMQLEVQILSLGNVCLYNAYIP--SHSNR---KTVPISSLAEQLTKKSLPI 1052 Cryptosporidium muris RN66...
Q5CR33                         970 WDKLVI--Eq-----kDGTVQNIIDYLTNKMNLETQIISFGNICLYNAYIP--NHQER---KCIPIALLIEQITKKKLHV 1037 Cryptosporidium parvum...
XP_001617346                  1026 WDKIQV--Qi-----eNGTIKNLIDHIGEQFGVEVNLISVGNACLYNCYLP-AHNKER---LNKPIHEIYAEITKQKLLD 1094 malaria parasite P. vivax...
Q4N4F1                         902 WNKLIVliP-------NGTVKQLIDWIRSKFNIEVIILSAGNLCIYNSFLP-QHRNER---LNAVITELVEKLGKKKIGV 970  Theileria parva...
Q23QY3                         995 WDKLFV--QG------PLTIQGLKDYFNDKYQVNISILSVGKICLYNSYMT--EAAER---ESWDIAQGVEKLGGQPIPD 1061 Tetrahymena thermophila SB210...
XP_001024914                   952 WDKIDV--VG------PLTVQGLLDYFSQQYQVKLSIISVAKICIYNSYAG---DSER---LTQDIAALYEKLNKAPISQ 1017 Tetrahymena thermophila SB210...
EGR27187                       933 WDKIEI--NG------PMKLSQLIDNFKDQYKVKLSIISVGKLCIYNVYGG-QQQQDL---LNQDILELYQKLQKQKVPA 1000 Ichthyophthirius multifiliis...
Q22KT5                         909 WEKIIV--DK------PVSIEELIDSFSNMYNVSINSIYVNNVQVWQSN--PLESKDNlniMKMNLLKAYEFESGTKMAK 978  Tetrahymena thermophila SB210...
WGS:AAGF:cds.TTHERM_00125358A  965 WDFIII--NG------PMRVSEFRDYFLEHYDVIINKIYYENKFLFDQNEQDAQQHEQ-----MDIQDLFELVFENKIPE 1031 Tetrahymena thermophila SB210...
6DC6_A                         987 HVRALVLELCCND-ESG-EDVEVPYV 1010
EEA05978                      1053 NRNYLALEASCCDtEDG-TDVIIPTI 1077 Cryptosporidium muris RN66
Q5CR33                        1038 TKNSIALEVSCCDiDDGvDTI-IPSI 1062 Cryptosporidium parvum
XP_001617346                  1095 DKNYIVVEASCSDqDL--VDVLIPSI 1118 malaria parasite P. vivax
Q4N4F1                         971 GCSHLVIDASCTDsDD--VDVVIPTI 994  Theileria parva
Q23QY3                        1062 FKKFLELEICAET-QTG-EDALMPTI 1085 Tetrahymena thermophila SB210
XP_001024914                  1018 FKKFLEITASGETlNDG-VDVNMPIV 1042 Tetrahymena thermophila SB210
EGR27187                      1001 SKAFLEIIVNGETlDDS-TDCNMPVI 1025 Ichthyophthirius multifiliis
Q22KT5                         979 GINQLPIMITAK--TK--NDQPAMFT 1000 Tetrahymena thermophila SB210
WGS:AAGF:cds.TTHERM_00125358A 1032 YKQYLKFGIYASD-RKG-NECKMPFV 1055 Tetrahymena thermophila SB210
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