Conserved Protein Domain Family
Cmyb_C

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pfam09316: Cmyb_C 
C-myb, C-terminal
Members of this family are predominantly found in the proto-oncogene c-myb and the viral transforming protein myb. Truncation of the domain results in 'activation' of c-myb and subsequent tumorigenesis.
Statistics
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PSSM-Id: 401307
View PSSM: pfam09316
Aligned: 22 rows
Threshold Bit Score: 213.756
Threshold Setting Gi: 47213968
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q4VBE3       516 FSPSQFLNTsAQH-ENLEIEHSSLTSTPVCsSQKTTFSTSLL-RDHTPRLQKENHLLRTPAIKRSILDSTPRTPTPFKNA 593 tropical clawed...
AAT68100     380 FSPSQFLNMwTKQ-DTLDLENPSLTSTPVC-SQKAVVTTPLH-RDKTPLTQKENSLFITPN-HKSDLDTMPRTPTPFKNA 455 zebrafish
XP_027859727 370 FSPSQFLNLwTKQ-DSHDLENPSLTSTPVC-SQKVIVTTPLQ-RDKTPLTQKENSVFVTPN-HKSELSTTPRTPTPFKNA 445 Monterrey platy...
XP_005986845 453 FSPSQFLNFlTKQ-DALELESPSLTSTPVC-SQKVIVTTPLH-RDKTPLLQK-NSVFVTPN-NKSARDPTPHTPTPFKNA 527 coelacanth
Q03237       434 FSPSQFLNFwTKQ-DTLELENPSLTSTPVC-SQKVIVTTPLH-RDKTPLLQK-NSAFVTPD-QKYVVDNTPHTPTPFKNA 508 chicken
XP_006006862 484 FSPSQFFNIsCGN-EQFNLENPALTSTPVC-GQKA--TTPLL-KEAISKDQKENAGFRTPTIRRSILSTTPRTPTPFKNA 558 coelacanth
XP_005042184 487 FSPSQFFNTcSGN-EQFNFENPAFTSTPIC-GQKVLITTPLH-KEMTPQDQKENVGFRSPTMRRSLLGSTPRTPTPFKNA 563 Collared flycat...
XP_016848353 489 FSPSQFFNTcSGN-DQFNLENPTFTSTPVC-GQKVLITTPLHsKEMTPKDQKENAGFRTPTIRRSLLGTTPRTPTPFKNA 566 green anole
KAE8598925   194 ysPSQLLNVcSGTfEHLNHENLPLTSTPIC-GQK-ILATPLK-KQVTPKKDKENAGFRTPTIRRSLLAMTPRTPTPFKNA 270 tropical clawed...
KAE8576533   413 FSPSQFLNFwSRQ-DALELENPSLTSTPVC-SQKVVVTTPLH-RDKTPLLQK-NSIFITPN-HKFVGESVLHTPTPFKNA 487 tropical clawed...
Q4VBE3       594 LAAQEFKHGPLKLLHHTPSHLAEDIQEVIKQESDeSGIVPEhcHTEEPILKRIKq-eVESPTHKVGNFYFSSYWEG-ESL 671 tropical clawed...
AAT68100     456 ME----KYGPLRPLPPTP-NLEEDLKEVLRSEAG-IELIV---EDEAPAEKKRKq-vYRPPMKKVRKSLALDVIDCsESV 525 zebrafish
XP_027859727 446 ME----KYGPLQPLPQTP-NLEDDINEVILREAG-INMVV---VQATPPDPRRKt-mHRPPMKKVRKSLALDVMDC---- 511 Monterrey platy...
XP_005986845 528 LE----KYGPMKPLPPTP-HLEEDLQEVLRSEAG-IELLI---EDETQSEQKREqaqHRPPMKKVRKSLAMDILDK-ESS 597 coelacanth
Q03237       509 LE----KYGPIRPLPQTP-HLEEDLKEVLRSEAG-IELIIE--DDVKPHKQKRKqglRRSPIKKVRKSLALDIVDE-DMT 579 chicken
XP_006006862 559 LAAQEKKYGPLKLVLQPHAYLEEDIREVLKEETG-TDIFLNlgEEEELALQNCKs-eHDAPGKKVRKSLVLDAWEK-DEL 635 coelacanth
XP_005042184 564 LAAQEKKYGPLRLMSQPLAFSEEDIREVLKEETG-TDIFPK--DEDDTLYKNCKq-eH-NFSKKVRKSLVLDAQEK-EEA 637 Collared flycat...
XP_016848353 567 LAAQEKKYGPLKIVSQPLAYLEEDIREVLKEETG-TDIFFK--EEEDSVYRSCKl-eN-PSAKKVRKSLVLDPWEK-EEF 640 green anole
KAE8598925   271 LAAQEKKYGPLRAVMQPLVFVEEDIMEVLKEETG-KDVFIK--EKRASDCKPNKq-eHISTVRKVRKSLILDSWDK-EEL 345 tropical clawed...
KAE8576533   488 LE----KFGSLKPLPQTP-HLEEDLKEVLRSESG-IELIIV--DEPKLERQKRK---PHSPIKKVRKSLALDIIDK-DPK 555 tropical clawed...
Q4VBE3       672 NAQLFRQQSALD 683 tropical clawed frog
AAT68100     526 AARKQQIKATVK 537 zebrafish
XP_027859727 512 --RVVPISKRKS 521 Monterrey platyfish
XP_005986845 598 AVNPFPLKpesf 609 coelacanth
Q03237       580 QNMPALPKTICF 591 chicken
XP_006006862 636 HAQLFAEDTVPD 647 coelacanth
XP_005042184 638 GAQRLTEDNSLD 649 Collared flycatcher
XP_016848353 641 DSQFFTEDNGSD 652 green anole
KAE8598925   346 GTDYLAPDEVSE 357 tropical clawed frog
KAE8576533   556 PPSLTLSSAAST 567 tropical clawed frog
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