Conserved Protein Domain Family
PD-C2-AF1
?
pfam09310: PD-C2-AF1 (This model is not part of the current CDD release)
POU domain, class 2, associating factor 1
Members of this family are transcriptional coactivators that specifically associate with either OCT1 or OCT2, through recognition of their POU domains. They are essential for the response of B-cells to antigens and required for the formation of germinal centres.
Links
?
Statistics
?
PSSM-Id: 518819
Aligned: 4 rows
Threshold Bit Score: 366.193
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
XP_008119288   7 SAPEPPPpqpSPRPYQGVRVKEPVKELLKRKRGSLqnANGATAAATTVFFPHQSLPSYSPAGQVCADSEFVASPL--VDD 84 
Q90ZH6         7 SASEQQP---QPRPYQGVRVKEPVKELLKRKRGNV--HNATAAAATTVVLPHQPLPSYSPMGQPCIDVDAAAPALpgAEE 81  chicken
XP_001381387  31 SAPEQTPv--PPRPYQGVRVKEPVKELLRRKRGLA--SSGLTVAATTVVLPHQPLATYATMGPSCLDMEVPTSTV--TEE 104
XP_036751579   7 TAPEQAPa--PPRPYQGVRVKEPVKELLRRKRGHA--SGGAGVTPTAVVLPHQPLATYTTVGPSCLDMEVSASTV--TEE 80  Chinese pangolin

XP_008119288  85 GTLYSGWLAQPSPATLQPLTQWAAYPDYVPHEAVSCPYTGEMYVQPVCPSYTLVGTSSVLTYASQPLITNLAARStSAPA 164
Q90ZH6        82 GALCSSWLSQPSPSSLQPLTQWTTYPDYVSHEAASCPYTADMYIQPMCPSYTLVGPSSVLTYASQPLITNFTPRS-STPA 160 chicken
XP_001381387 105 GALCTGWLSQPAPATLQPLTPWTPYPEYMPHEGVSCPYSTDMYVQPVCPSYTVVGPSSVLTYASQPLITNFTTRN-ATPT 183
XP_036751579  81 GSLCAGWLSQPAPATLQPLAPWTPYTEYVSHEAVSCPYSADMYVQPMCPSYTVVGPSSVLTYASQPLITNVTTRAaATPT 160 Chinese pangolin

XP_008119288 165 VMPHLDMMEQQGPLSYFPWTQPISTLPAPSLQYQAASSALPAPQFLPLPVSVPETVSQDLEDTRKDLGGLSMEKLLLQEE 244
Q90ZH6       161 VVPQLEVTEQQPPLTYFPWAQPLSALPAPTLQYQPASSTLPTPQFVPLPISIPEPAPQELEDARRVIGTLPIEKLLLEDE 240 chicken
XP_001381387 184 SGPQLEGTEHQAPLTYFSWPQPISALPSSTLQYQSPAPSLPGPQFLPLPISIPEPVPQDLEDTRRAINTLPIEKLLLEEE 263
XP_036751579 161 VGPQLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPALQDMEDPRRPVSSLTIDKLLLEEE 240 Chinese pangolin

XP_008119288 245 NHGIFDLSNSLPVEG 259
Q90ZH6       241 DNDTYVLNHALSVEG 255 chicken
XP_001381387 264 ESDTYGMNHTLSVEG 278
XP_036751579 241 DNNAYALNNTLSVEG 255 Chinese pangolin
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap