Conserved Protein Domain Family
MHC2-interact

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pfam09307: MHC2-interact 
CLIP, MHC2 interacting
Members of this family are found in class II invariant chain-associated peptide (CLIP), and are required for association with class II major histocompatibility complex (MHC) in the MHC class II processing pathway.
Statistics
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PSSM-Id: 401300
View PSSM: pfam09307
Aligned: 8 rows
Threshold Bit Score: 120.294
Threshold Setting Gi: 0
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
PNI71944      19 DQRDLISn---NEQLPMLGRRPGAPEskcsRGALYTGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLENLRM 95  chimpanzee
1_pfamImport   1 QNQPLLA----ATSQPAVNAQGGRPS----RAHKVAGLTLLACVLIAGQVATTYLVLSQRSDIKSLEDQSKNLQSRLSVS 72 
NP_571665      6 QNESLIQr--vPSAETILG-RGDARNsn-tKALKITGLTVLACLLLAGQALTAYMVWGQKQHINALTSGQEKLKAELTRK 81  zebrafish
XP_015205517   5 QHDALLKnegpPSEETVVNVQTGQRSss-nRGYKIAGFTLLACLLIAGQAVTVYFVMSQKGQITTLEQHTENLKKQLNTR 83  spotted gar
XP_014351519   4 ERQDLLRgnepSLSESVVNINNEGSRst-kRTILWTGLSIFVALLIAGQAVTVYFVMQQKGQITTLEQHSKNLELTLRMK 82  coelacanth
P04441         3 DQRDLISn---HEQLPILGNRPREPErc-sRGALYTGVSVLVALLLAGQATTAYFLYQQQGRLDKLTITSQNLQLESLRM 78  house mouse
XP_005053523   4 EQRDLISd---RG-SGVLSVGDAQRSgl-rRKAAFSTLSILVALLIAGQAVTIYFVYQQSGQISKLTKTSQKMQLDALQM 78  Collared flycat...
XP_015149240   4 EQRDLISs---DGSSGVLPIGNSERSsl-gRRTALSALSILVALLIAGQAVTIYYVYQQSGQISKLTKTSQTLKLESLQR 79  chicken
PNI71944      96 KLPKPPKPvskmrMATPLLMQALPMGALPQGPMQ 129 chimpanzee
1_pfamImport  73 RSGSASVP-----MRMPMNAFPKVLDVVDEEAST 101
NP_571665     82 MSAGA--Pk---aMSLPMNSMPLLKDYSDPTSDQ 110 zebrafish
XP_015205517  84 KPAPPSAPk---mLHMPMFNMPLLMDYSEDSKKV 114 spotted gar
XP_014351519  83 TFPKPKAPr----MMMPM-AIPLA--YSEDVDPK 109 coelacanth
P04441        79 KLPKSAKPvsqmrMATPLLMRPMSMDNMLLGPVk 112 house mouse
XP_005053523  79 KLPASAKPvnkmkMAK--ANTPLVMSALHPAPfe 110 Collared flycatcher
XP_015149240  80 KMPIGTQPankmsMST--MNMPMAMKVLPLAPSV 111 chicken
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