8VRW


Conserved Protein Domain Family
MHC2-interact
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pfam09307: MHC2-interact (This model is not part of the current CDD release)
CLIP, MHC2 interacting
Members of this family are found in class II invariant chain-associated peptide (CLIP), and are required for association with class II major histocompatibility complex (MHC) in the MHC class II processing pathway.
Links
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Statistics
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PSSM-Id: 518817
Aligned: 5 rows
Threshold Bit Score: 134.627
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8VRW_C        29 MDDQRDLISn---NEQLPMLGRRPGAPEskcsRGALYTGFSILVTLLLAGQATTAYFLYQQQGRLDKLTVTSQNLQLENL 105 human
1_pfamImport   1 EIQNQPLLA----ATSQPAVNAQGGRPS----RAHKVAGLTLLACVLIAGQVATTYLVLSQRSDIKSLEDQSKNLQSRLS 72 
4_pfamImport   1 EEQHDALLKnegpPSEETVVNVQTGQRSss-nRGYKIAGFTLLACLLIAGQAVTVYFVMSQKGQITTLEQHTENLKKQLN 79 
P04441         1 MDDQRDLISn---HEQLPILGNRPREPErc-sRGALYTGVSVLVALLLAGQATTAYFLYQQQGRLDKLTITSQNLQLESL 76  house mouse
XP_014351528   2 TDERQDLLRgnepSLSESVVNINNEGSRst-kRTILWTGLSIFVALLIAGQAVTVYFVMQQKGQITTLEQHSKNLELTLR 80  coelacanth

8VRW_C       106 RMKLPKPPKPvskmrMATPLLMQALPMGALPQGPMQ 141 human
1_pfamImport  73 VSRSGSASVP-----MRMPMNAFPKVLDVVDEEAST 103
4_pfamImport  80 TRKPAPPSAPk---mLHMPMFNMPLLMDYSEDSKKV 112
P04441        77 RMKLPKSAKPvsqmrMATPLLMRPMSMDNMLLGPVK 112 house mouse
XP_014351528  81 MKTFPKPKAPr----MMMPM-AIPLA--YSEDVDPK 109 coelacanth
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