Conserved Protein Domain Family
DUF1968
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pfam09291: DUF1968 (This model is not part of the current CDD release)
Domain of unknown function (DUF1968)
Members of this family are found in mammalian T-cell antigen receptor, and adopt an immunoglobulin-like beta-sandwich fold, with seven strands in two beta-sheets in a Greek-key topology. Their exact function has not, as yet, been determined.
Links
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Statistics
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PSSM-Id: 518805
Aligned: 11 rows
Threshold Bit Score: 101.762
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AAI49621      19 PTVYQLRSP--QSSDTSVCLFTDFDSnQVNMEKimgSEG-STVHKTNSTVLNMEILGSKSNGIVTWGNTSDAGCEYTFNE 95 
5_pfamImport   1 PAVYQLKSP--KLGNTSVCLFTDFPS-NNTNSS---NNE-PDVFMSDKTVLDMRSTGSKSNGVLAWSQKAEFACADTFME 73 
4_pfamImport   1 PSVYQLRGS--KSSNTSVCLFTDFDS-KANVSH---GSD-PGVFGSGQTVVDMKSTDSKSNGALAWSNNTGFECNYVFGE 73 
8_pfamImport   1 PTVYQLRSP--ESSNTSVCLFTDFDSnQINLTQi-gGYEwNMVHKTDSTVLNMEILGSKSNGIVTWGNTSDSGCTNTFNE 77 
1_pfamImport   1 PRMYHLKKP--RVNDLSVCLFTDFGNeEVNMMG-------INNIKRTPSMVAEKRLASKSLGIVAWNNNLDWKCQAKISN 71 
7_pfamImport   1 PAVYQLKSP--ESSNISVCLFTDFDS-EVNVNP---STE-SNMIRLKSTSLDMKTMDSKSNGALAWGNSFDLGCNSTFNY 73 
2_pfamImport   1 PAVYQLRSP--TSSNTSVCLFTDFDS-KVNVSQ---DPN-STVISSNSTALDMRAMDSKSNGALHWSDSPDFMCDNTFET 73 
3_pfamImport   1 PAVYQLRSSdsKSSKLSMCLLTDFDS-QTNVSQ---RTE-SETVFTSHTVLNMKSLDSKSYGALAWSQNSRLSCQDAFSN 75 
P01849         6 PAVYQLKDP--RSQDSTLCLFTDFDS-QINVPK---TME-SGTFITDKTVLDMKAMDSKSNGAIAWSNQTSFTCQDIFKE 78  house mouse
6_pfamImport   1 PAVYQLKDP--QSDNITLCLFTDFDS-QTNVSQ---SAS-SEAFVSGNTVMDMKAMDSKSNGAIAWSNQTSFSCKDAFKK 73 
P01848         6 PAVYQLRDS--KSSDKSVCLFTDFDS-QTNVSQ---SKD-SDVYITDKTVLDMRSMDFKSNSAVAWSNKSDFACANAFNN 78  human

AAI49621      96 t----IPFASSL 103
5_pfamImport  74 -----DPFYSNS 80 
4_pfamImport  74 s----TDFYSSS 81 
8_pfamImport  78 n----IEFVDNF 85 
1_pfamImport  72 i----TYSLSNS 79 
7_pfamImport  74 ------TFHSSS 79 
2_pfamImport  74 -----GAFYPSS 80 
3_pfamImport  76 -----HTFVSSS 82 
P01849        79 t----NATYPSS 86  house mouse
6_pfamImport  74 -----NASHPTS 80 
P01848        79 siipeDTFFPSP 90  human
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