3EE6


Conserved Protein Domain Family
Pro-kuma_activ

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pfam09286: Pro-kuma_activ 
Pro-kumamolisin, activation domain
Members of this family are found in various subtilase propeptides, and adopt a ferredoxin-like fold, with an alpha+beta sandwich. Cleavage of the domain results in activation of the peptide.
Statistics
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PSSM-Id: 401284
Aligned: 88 rows
Threshold Bit Score: 80.7244
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3EE6_A   33 PGWVSLGRADPEEEL-SLTFALRQQNV--ERLSELVQAvSDPSSPQYGKYLTLENVADLVRPSPLTLHTVQKWLLAAGAQ 109 
Q7NSA7   25 QDLGKVEQAAPAQKL-TVTIALSLRDR--DAAARYLQEvHTPSSPNYHKFLTPSEFRARYAPTEASLAKVAARLQAAGLS 101  Chromobacterium vio...
Q1IUJ5   56 AKSADKGRLAGDRNLgQMLLMLSPTKEqnTALEAVIKAeHTPGSAKYHHWLKASEIATKYGVSEPDTTAVRGWLASQGFE 135  Candidatus Koribact...
Q1IVJ0   56 KNAHDLGEVDGGMKLqRMMLVLKPSAEqqASLQRLLDSqQNKKSPNHHKWLTPEKFAASYGPSEEDVAKVKNWLESQGMS 135  Candidatus Koribact...
Q1IVJ7   59 KAARDAGAVDSNLSLdRILVLLQPSAKqsDALKLYLDDlQNTDSKNYHQWLTPEQYAQKFGPTDADMQKVTDWLQSHGFK 138  Candidatus Koribact...
Q1IUI6   64 RASVDQGVADGSLALsRMILILRRSPAqeLELQKYLDDqKNPKATAYHHWLTPQQFGERFGSNGHDVATITQWLRSHGFT 143  Candidatus Koribact...
Q01ZH2   65 SAANDIGAMDPATTLpAMTLVLRQSAAqqADLANLLAAqQDPASPEYHHWLTPEQYADRFGASADDVAKITAWLAQHNLQ 144  Candidatus Solibact...
Q01UW0   45 LPQFDRGSVDPGMAIdHATVLLKPDS----SLNDFLANqQLPGSPDYHRFLNSDEFGQRFGLSSADLAKVVSWLQSEGLK 120  Candidatus Solibact...
Q01UW2   46 QPQFDRGLVDPAMRIpRATLILKPAK----SLAAFLAAqQIPGSPEYRQFLSPEQFADRFGLTTDDLTKVVGWLESQGLK 121  Candidatus Solibact...
Q82AV6   39 TATADKGATDNGSQV-SARVYLAGKDA--AGLAAYAKAvSDPNSASYGKYLSAQQAQARFGATKAQVAEVTDWLKSAGLK 115  Streptomyces avermi...
3EE6_A  110 KCHsvITQDFLTCWLSIRQAELLLpGAEFHHYV---GGPTETHVVRSPHpyQLPQALAPHVDFVGGLHRF 176 
Q7NSA7  102 VKR--IGSTLLQVSGPAATVQKAF-GAEVHVFQnksVVQGAAARYTAPVraSTPGIDLSDVQAVIGLDSR 168  Chromobacterium violaceum
Q1IUJ5  136 VKHvaNSRRFVVFSGTVAQVEAAF-HTQMHQYE----LSGNSFIANSQEv-QIPAALAPVVRGVVRLTST 199  Candidatus Koribacter versati...
Q1IVJ0  136 VSKigNGRQWIEFSGSAHQVGTAF-GTSLHYFE----TNGERHMANATEi-SIPRAISPVVSGVLSLHNF 199  Candidatus Koribacter versati...
Q1IVJ7  139 ISEvaAGRQWIEVAGTAAQVRTAF-NTEIHKYH----LNGKDYFANASDv-SLPRALSSVVRGVLSLNNF 202  Candidatus Koribacter versati...
Q1IUI6  144 IDSvaKGNNVILFSGTHAQLSAAF-HTSLHQYK----VNGKLQIANATNp-QIPAALALAVVGIAKLNDF 207  Candidatus Koribacter versati...
Q01ZH2  145 VTAvgRGRMSVTFTGTAGDVEQAF-QVSMHRYS----VNGRNHFANTAEp-SLPAAMEPAIRSIHGLHDF 208  Candidatus Solibacter usitatu...
Q01UW0  121 VDEvaRGRHWITFSGTAAQAARTF-HTEFHRFQ----VEGRMHFGNAGEp-AIPAALESVVGGFTGLDDF 184  Candidatus Solibacter usitatu...
Q01UW2  122 ADRiaRGRNAITFSGTAEQAARTL-KTEFHRYQ----VNGKMHFAAAAEp-SIPEALGDVVAGFTGLDDF 185  Candidatus Solibacter usitatu...
Q82AV6  116 VTG--STQHYVTVTGDVAAAEKAF-GTQLHNYV----KGGKTYRAPAKTa-SAPAALDGAVLTVTGLDNA 177  Streptomyces avermitilis
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