8EBS


Conserved Protein Domain Family
XPC-binding
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pfam09280: XPC-binding (This model is not part of the current CDD release)
XPC-binding domain
Members of this family adopt a structure consisting of four alpha helices, arranged in an array. They bind specifically and directly to the xeroderma pigmentosum group C protein (XPC) to initiate nucleotide excision repair.
Links
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Statistics
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PSSM-Id: 518798
Aligned: 82 rows
Threshold Bit Score: 43.2673
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8EBS_I        276 LEFLRNQPQFQQMRQIIQQNPSLLPALLQQIGRENPQLLQQISQHQEHFIQMLNEPV 332  human
XP_069923111  282 LDFLLNHPEFQQLRQIIQHDPSLLPEVLQGIRPRNPQLLAQFSQYQGYLSRMLSAPV 338 
Q38B86        180 PRSLQDHQTMVSIVEYVDRDPTRLRDVLRTILEEEPDLFRWIEANSEVFLAIINGPV 236  Trypanosoma brucei
CBJ25906      178 LEDFRGHPQFNELKRLVQRDPTQLSSILQMIGRQSPNLLARIHENQGDFIALMNEPI 234 
XP_049535116  268 LAFLRGNPVFFEMKRLLQEDPSLLPYLMQRIQYSNPNLMRIISENQEEFLAMINENS 324 
Q7PRQ2         84 LAFLRDNPVFEDMRRILRDDPSMLPYLMRRMQASNPDLLNIIAEYQDEFLALINEGS 140  Anopheles gambiae str. PEST
XP_002058647  179 LNYLATDPRFAHVRDLIRQNPELLELVLTHLRESDPAAFEAIRSNQEEFISMLNEPT 235 
XP_001964524  189 LQPWMSDPRFARVRDMLRQNPELLEVVLSRLAETDPSAFEAIRDHQDEFLSMINGSS 245 
EDX14159      172 LQHLLADPSITRMREMLNQNPELMHRLMDRLAETDPATFEALGSNQD-FLNMISGGA 227 
Q9VCD5        172 LQQLMADLNITRMREMINQNPELIHRLMNRLAETDPATFEVFQRNQEELMNMISGGA 228  fruit fly
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