3OVU


Conserved Protein Domain Family
AHSP
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pfam09236: AHSP (This model is not part of the current CDD release)
Alpha-haemoglobin stabilising protein
Alpha-haemoglobin stabilising protein (AHSP) acts a molecular chaperone for free alpha-haemoglobin, preventing the harmful aggregation of alpha-haemoglobin during normal erythroid cell development: it specifically protects free alpha-haemoglobin from precipitation. AHSP adopts a helical secondary structure consisting of an elongated antiparallel three alpha-helix bundle.
Links
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Statistics
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PSSM-Id: 518771
Aligned: 14 rows
Threshold Bit Score: 126.387
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3OVU_A         4 KANKDLISAGLKEFSVLLNQQVFNDPL-VSEEDMVTVVEDWMNFYINYYRQQVTGEPQERDKALQELRQELNTLANPFLA 82  human
XP_017193256   5 PTNKDLISMGLKEFNVLLNQQVFSDPL-LSQEAMQTVLDDWVNLYVNYYRQQMTGEQQELDKALEELRLELNGLAKPFLN 83 
XP_003794315   5 QANEDLISAGVKEFNILLNQQVFNEPF-VSEEAMETVVNDWVNFYMNYYKKQMTGEQGEQEKALQELKQKLNSLANPFLA 83 
Q865F8         5 QTNKDLISKGIKEFNILLNQQVFSDPA-ISEEAMVTVVNDWVSFYINYYKKQLSGEQDEQDKALQEFRQELNTLSASFLD 83  domestic cattle
Q9CY02         5 QSNKDLISTGIKEFNVLLDQQVFDDPL-ISEEDMVIVVHDWVNLYTNYYKKLVHGEQEEQDRAMTEFQQELSTLGSQFLA 83  house mouse
XP_027241574   5 QTNKELISEGIKQFNVLLGQQVFDDPL-IPEENMVTVVNDWVNLYINYYKPLVFGKQQEQDKALQELQQELNTLGSQFLT 83 
XP_006148162   5 QVNKDIIATGMKKFSVLLDQQVFSEPP-ISEEAMVVVVNDWVNFYVNYYGQQVTGEQQEQDRALNELRQELTTMASPFLA 83 
2_pfamImport   1 QANKDLISTGMKEFSILLNQQDMRDNP-IPEEAMVIVVNDWMSFYINYYRQKMTGEQQEQDRALQELQQGLNTLANPFLT 79 
XP_001515563   5 HSNQDVINSAMAAFQALLNQQVFSPQIpIPMEAMKIIVRDWIEFYISYFAPKLRGDRQERERAQEDLWETLQAIARPFLD 84 
XP_003761380   5 QSNQDVISSAMQEFSKLLDQQEFTKPA-FSETDMVTIVDDWIKFYLSYYSKKMTGNEQEQERAMQKLQEELRTSASPFLD 83 

3OVU_A        83 KYRDFLKS 90  human
XP_017193256  84 KYSVFLKS 91 
XP_003794315  84 KYRAFLKS 91 
Q865F8        84 KYRNFLKS 91  domestic cattle
Q9CY02        84 KYRTFLKS 91  house mouse
XP_027241574  84 KYRTILKS 91 
XP_006148162  84 KYRAFLKS 91 
2_pfamImport  80 KYRDFLKT 87 
XP_001515563  85 KYRDFLNA 92 
XP_003761380  84 KYRAFLKT 91
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