Conserved Protein Domain Family
Endonuc-BglII

?
pfam09195: Endonuc-BglII 
Restriction endonuclease BglII
Members of this family are predominantly found in prokaryotic restriction endonuclease BglII, and adopt a structure consisting of an alpha/beta core containing a six-stranded beta-sheet surrounded by five alpha-helices, two of which are involved in homodimerization of the endonuclease. They recognize the double-stranded DNA sequence AGATCT and cleave after A-1, resulting in specific double-stranded fragments with terminal 5'-phosphates.
Statistics
?
PSSM-Id: 370355
View PSSM: pfam09195
Aligned: 9 rows
Threshold Bit Score: 167.167
Threshold Setting Gi: 122398927
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q2Y5S5         25 NAAQVLAT-GCPNEFQEIIEALRVFRLTLADIRKPGGNESDIPKRI---------SGLLRAKGW-METRIKGdllitkvs 93  Nitrosospira m...
Q5LUX4         35 SAAAILAQ-RAPGELAAILRILDAFTISRTEIRSPGGNRMSATTRF---------ADLAAAEGFhQEVRIEAdltv---- 100 Ruegeria pomeroyi
Q16BA4         51 HASAVLFG-DHPDEWRDLMDVLTDFRLKKSHITVGGKNKSQLAASI---------DEFLENRGW-KETRFDTki------ 113 Roseobacter de...
WP_011803888   21 HACAILKH-DFPQEWDDIVHVLGNFRLRRSWLTVGGGRKSKVSDAI---------DSGLYALGW-KEKQFQTei------ 83  Acidovorax sp....
Q47A78         10 FAEEIVQHpKHQAAWNEIQAILSGAPLFVYPNKSSSNDKLDVVQQVmnt---yfdRVMAIDHGWeYHPLA---------- 76  Dechloromonas ...
jgi:Dred_1461  12 SAHDFITP----DVEAEINQLLLEPTIDLSSLSRSHYNQLL--------------REMFKRNGWqNSPSL---------- 63  Desulfotomacul...
jgi:Exig_2377  11 NGNSVIKE-SYSNELNEILSAIKSIDASKFKTKISKEKTSLGKMLYspvalnkelKKILNPLGWkELKHEAI-------- 81  Exiguobacteriu...
Q1GQR2         11 NGFEFLKY-HKAHIWDDLEAVVAAVDAEACRTKASAEARKEGRLLYspvdmnkefARLFADHHWtERRVTNW-------- 81  Sphingopyxis a...
CDC05318       12 fAEQVFNS--RLQLKQEINEMLLEACKDLSVLGRPAFNRIL--------------KDLFVEKNWiSQPRV---------- 65  Clostridium le...
Q2Y5S5         94 gtidknlgekdlEGMEENESdtlekieelknkgqverivrenfldGHKVDYVK----KRVAFDLEWNSKDQTFdRDLYA- 168 Nitrosospira m...
Q5LUX4        101 ---------rlrEGKGENAPeidril-------------radyihNHLVDFWR----GRVAFDYEWNSKDQTYdRDLYA- 153 Ruegeria pomeroyi
Q16BA4        114 ----------vvDNVETETP-------------------------THKIDMFK----NGVAVEIEWNNKDPFYdRDLNN- 153 Roseobacter de...
WP_011803888   84 ----------llDGQRQESP-------------------------THQIDCFK----NRVALEIEWNNKDPFYdRDLNN- 123 Acidovorax sp....
Q47A78         77 ------------TSIEN-SG--------------------------LAADFKKtfgdIVVQAEVQFGNMSRWY-SDVFK- 115 Dechloromonas ...
jgi:Dred_1461  64 ------------FHDPVNPL--------------------------AKIELLK----NNIGLEIGFRHVSLTG-HNLLKf 100 Desulfotomacul...
jgi:Exig_2377  82 ------------YSSDNPDIsdt--------------------laHREMDFVK----NEVGVEVQFGKYAFMA-YDICSk 124 Exiguobacteriu...
Q1GQR2         82 ------------LSEDTSLLrdimslepqaqkemiearglepimtYNQTDFVK----DRVAVEIQFGKYAFVA-HDLFVk 144 Sphingopyxis a...
CDC05318       66 -------------SPEMKAY--------------------------SKFDFMK----ERVAVEVQFGHASFIG-IDLLK- 100 Clostridium le...
Q2Y5S5        169 -FRA--FHECDLIDAAILLTRSASLNAVFeklgpelnsdgtpktskngkpKLikTKYGASTTWMGKLLYRL-NAGRHG-G 243 Nitrosospira m...
Q5LUX4        154 -FRS--FFEAGVIDVGVIVTRALPPEFFQslgycld-------kdgnetaSTvaAKFGASTTGTHKLLSRI-AAGRSG-G 221 Ruegeria pomeroyi
Q16BA4        154 -FRL--LHALRTVSVGVLITRSDELQDIFkk-----------------lgRG--SSYGNSTTHMSKLVPRI-EGGGAG-G 209 Roseobacter de...
WP_011803888  124 -FRL--LFDLRAVSVGVIVTRCDHLQEIFda-----------------igRG--PSFGASTTHMSKLLPRI-RGGGGG-G 179 Acidovorax sp....
Q47A78        116 -FQT--AYSQSLINIGLSVVPMNSLAK----------------------------RIDSNIVNFERTEREL-PSAKLSiT 163 Dechloromonas ...
jgi:Dred_1461 101 qLSP--LHNSDKIDVGIFIVSTNNFQKQI---------------------RKtfCHNWTGAMSFEKTDRYL-RNFKTAiQ 156 Desulfotomacul...
jgi:Exig_2377 125 -MPI--FKNKGYIEVGIEIVPMKAFAK----------------------------YMSTGVSYYEQITWDLeNRGVSNlD 173 Exiguobacteriu...
Q1GQR2        145 -HMS--FFISDDIDVGIEVVPMKSMER----------------------------EMSSGVPYYERDLFNLmRQGRGIpA 193 Sphingopyxis a...
CDC05318      101 -FQMasYSNLDLIDFGVYITTTKAMQKYL---------------------KTkyNRNWDGSLNYEKVVKYL-PYFKSAiQ 157 Clostridium le...
Q2Y5S5        244 CPVLALGIT 252 Nitrosospira multiformis ATCC 25196
Q5LUX4        222 CPVLVFGIR 230 Ruegeria pomeroyi
Q16BA4        210 CPILTFGIK 218 Roseobacter denitrificans OCh 114
WP_011803888  180 CPILVLGIS 188 Acidovorax sp. JS42
Q47A78        164 LPILLIGLE 172 Dechloromonas aromatica RCB
jgi:Dred_1461 157 IPIYLIGID 165 Desulfotomaculum reducens MI-1
jgi:Exig_2377 174 IPVIVIGID 182 Exiguobacterium sibiricum 255-15
Q1GQR2        194 VPIILVGVA 202 Sphingopyxis alaskensis
CDC05318      158 VPIYVIGID 166 Clostridium leptum CAG:27
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap