Conserved Protein Domain Family
Maf1

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pfam09174: Maf1 
Maf1 regulator
Maf1 is a negative regulator of RNA polymerase III. It targets the initiation factor TFIIIB.
Statistics
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PSSM-Id: 401206
View PSSM: pfam09174
Aligned: 89 rows
Threshold Bit Score: 104.628
Threshold Setting Gi: 74831749
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_006695441  44 VTGSCDLYT--------------TKAAGSDKKLY-------------------------KNITQSLEaqaqaQQQNNGQG 84  Chaetomium ther...
Q8I1S2       157 KYNDNNKYNdneninndknkyydNENINNDKNKYndneninndnnntcyinipdsiltnKNVKKKKIpevinN------- 229 Plasmodium falc...
Q57YV3        26 MTVRLEAFT--------------CRCTRKKKLLA-------------------------ASIAEYANkt----------- 55  Trypanosoma brucei
CAM70669      26 ITMRLEAYT--------------CRHTKEERQIA-------------------------NSIACYQNnvq---------- 56  Leishmania infa...
XP_002489362  25 VRGGCDLFT--------------TKPVGSDKKLY-------------------------KTIDKHLDd----ILQESLNW 61  Komagataella ph...
XP_001645936 122 ndqnlkdlvtnsdneylssssieSSSNHGEK----------------------------SRRSSSVAvngssSNNKFKVS 173 Vanderwaltozyma...
CCE64277     188 NNNSNNNNN--------------NNNNNNDLKSD-------------------------DSKVNTFNdttlqNNNKFKVT 228 Tetrapisispora ...
Q6FIZ7       158 sSSSVESLT--------------HKNKE-------------------------------RRTSSLSStggkvDKLRADSS 192 [Candida] glabr...
XP_003668051 177 skssssLYN--------------SMNKRNDSNRD-------------------------ESTTNGINn---dNNSTEDGE 214 Naumovozyma dai...
EFD94992      26 iTTRIELYGfr-----------vSQATSSEQDRD-------------------------AEFQIQMArsygsSV------ 63  Giardia lamblia...
XP_006695441  85 Tragsassppqhpq------------------------------prrdsstlsvsstSRRLSSSATDSAFG--------- 125 Chaetomium ther...
Q8I1S2       230 ------------------------------------------------------------------N------------- 230 Plasmodium falc...
Q57YV3        56 ------------------------------------------------------------------tPPLRplcsanapv 69  Trypanosoma brucei
CAM70669      57 -----------------------------------------------------------------ltPPISplptigaya 71  Leishmania infa...
XP_002489362  62 NmshspptasritdnvdfqtrfsrrassssivkptlkrksfnhhqattlskslenidINESALYDEETPFG--------- 132 Komagataella ph...
XP_001645936 174 Kisknr-----------------------------------------------rrssANHDPSNINIGPFG--------- 197 Vanderwaltozyma...
CCE64277     229 Kthpnr-----------------------------------------------rrssIQDAPPNISIGPFG--------- 252 Tetrapisispora ...
Q6FIZ7       193 Tandit-----------------------------------------------arsvLNDTSRTLNLGPFG--------- 216 [Candida] glabr...
XP_003668051 215 Kkkkir-----------------------------------------------rrssLNDTSSNITIGPFG--------- 238 Naumovozyma dai...
EFD94992      64 ----------------------------------------------------------------ESQSPFGslnssit-- 77  Giardia lamblia...
XP_006695441 126 ------------------------SLEDVSSRRVFAYLIATLNASH-PD-YDFSQvLRPADFKRERVLRRVMAHIDST-L 178 Chaetomium ther...
Q8I1S2       231 ---------------------------GKEKKSILTNIINILNYVF-PD-YEFKY-LNNSNYKYIKNINSVIDNINYN-L 279 Plasmodium falc...
Q57YV3        70 ppll-------nlsddsvhvvptePVEPSDIDDRLVFLVAALNSIYgEDgYDFSV-LTEEDFVPC-DEAHVRAEVNNT-L 139 Trypanosoma brucei
CAM70669      72 gftqealpplvlggsaenvtasysLVSPNEIDDRLVYFVAALNTVYeSDgYDFSV-LRENDFVRY-TEPQFRTEVSST-L 148 Leishmania infa...
XP_002489362 133 ------------------------PITSTHSRKIFSYLIGILNASY-PD-HDFSS-LTPDYFTAVDSANSMMNRFNSIvL 185 Komagataella ph...
XP_001645936 198 ------------------------PINETASRRIFAYLIAILNASY-PD-HDFSS-LEPTDFVK-SSLKELISKFENS-L 248 Vanderwaltozyma...
CCE64277     253 ------------------------PISETASRRTFAYLIAILNASY-PD-HDFSS-LEPTNFVK-STIKQMVSKIENS-L 303 Tetrapisispora ...
Q6FIZ7       217 ------------------------PINEPSSRRTFAYLIAILNASY-PD-HDFSL-LEPTDFKR-SSIKSFIAKFENS-M 267 [Candida] glabr...
XP_003668051 239 ------------------------PIKEPASRRTFAYLIAILNASY-PD-HDFST-LEPTDFTR-SSLKSFISKFESS-L 289 Naumovozyma dai...
EFD94992      78 ------------------safteeNLNNPATRQIYLQVIRALSQAY-PH-FDFTL-IQPSRFFWV-PYSVCQTVIDST-L 134 Giardia lamblia...
XP_006695441 179 SS--------VRPqkgddaetaalrassytsptqlildgrgggggdginpapywgpQMWALIDKQMALEE--CAVYSYA- 247 Chaetomium ther...
Q8I1S2       280 FYiieniyrgFNK-------------------------------------------KIWKILKELIDFKY--CDVYTYL- 313 Plasmodium falc...
Q57YV3       140 RS--------FPSscgp------------------------------------avgQFWVRVTEHASDASqgCEYFRFAs 175 Trypanosoma brucei
CAM70669     149 QS--------LPEqcrp------------------------------------avqRFWPTIEEVVENAEsgCEYYEFRc 184 Leishmania infa...
XP_002489362 186 SLgyk---dqIDDgdk-------------------------------------dinWIWETINSHMDIQD--CSIYALE- 222 Komagataella ph...
XP_001645936 249 YSlg----kqPEE-------------------------------------------WMWEIINSHMDLSD--CVIYRYD- 278 Vanderwaltozyma...
CCE64277     304 YSlg----kkPDE-------------------------------------------SMWEIINSHMDFSD--SVIYEYD- 333 Tetrapisispora ...
Q6FIZ7       268 YSlg----rkPEE-------------------------------------------WIWEVINSHMTLSD--CVLYQYC- 297 [Candida] glabr...
XP_003668051 290 YSlg----kqSEE-------------------------------------------WIWDIINPHMTLAD--CVVYLYS- 319 Naumovozyma dai...
EFD94992     135 IStlsd-ysaIRP-------------------------------------------SLWLALTDIAPADA--SSVYTVD- 167 Giardia lamblia...
XP_006695441 248 PEEG--AFd-EEE-GAIWALHYFFFNKALKRVCYLY 279 Chaetomium thermophilum var. thermophilum DSM 1495
Q8I1S2       314 NDTDndPYvdKES---ISSFNYFFFAKKNKRILFIS 346 Plasmodium falciparum 3D7
Q57YV3       176 PSCd--PMa----sRALFSQHYFLYNKRTRLLVSLl 205 Trypanosoma brucei
CAM70669     185 PSCd--PLa----dTTVYARHYFVYNRRKKVLVLLv 214 Leishmania infantum JPCM5
XP_002489362 223 PKd--gVLadLEP-NTLWCLMWFIFNKKRKRVAFLh 255 Komagataella phaffii GS115
XP_001645936 279 PNK---SFldDEP-GHLWSLNWFIFNKKRKRVAYLY 310 Vanderwaltozyma polyspora DSM 70294
CCE64277     334 PSK---LLldDEP-GYLWSLNWFIFNKKRKRVAYIY 365 Tetrapisispora phaffii CBS 4417
Q6FIZ7       298 PTQ---SFldDEP-GHLWSLIGFFFNKKRKRVAYVY 329 [Candida] glabrata CBS 138
XP_003668051 320 PAK---SFleDEP-GYLWSLMGFLFNKKRKRVAFLY 351 Naumovozyma dairenensis CBS 421
EFD94992     168 PS----PYypFEDtDGVWSHNFIFYSAERSTVLLFi 199 Giardia lamblia ATCC 50803
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