1LNS


Conserved Protein Domain Family
PepX_N
?
pfam09168: PepX_N (This model is not part of the current CDD release)
X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal
Members of this family adopt a secondary structure consisting of a helical bundle of eight alpha helices and three beta strands, the last alpha helix connecting to the first strand of the catalytic domain. The first strand of the N-terminus also forms a small parallel beta sheet with strand 5' of catalytic domain. The domain mediates dimerization of the protein, with two proline residues present in the domain being critical for interaction.
Links
?
Statistics
?
PSSM-Id: 518730
Aligned: 22 rows
Threshold Bit Score: 166.665
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
1LNS_A         1 M----RFNHFSIVDKNFDEQLAELDQLGF---RWSVFWDEKKILKDFLIQSPSDMT----------ALQATAELDVIEFL 63  Lactococcus lactis
Q9CE01         1 M----RFNHFSIVDKNFDEQLAELDQLGF---RWSVFWDEKKILKDFLIQSPTDMTv----------LQANTELDVIEFL 63  Lactococcus lac...
WP_014024201   1 M----KFNHFSIVEKTFDEQLIELDHLGF---TWSVFWEEKKILKNFLMVAPVDSEs----------IQATPTASFHEFL 63  Lactococcus gar...
Q04E49         1 MknnfKYNAFT--DDSFFDPFDELKRINLfddSFFENSF-HDNLKIFFKRMFPNCHsfeakkeaekAILVNGKNDLSTYL 77  Oenococcus oeni...
Q8DVS2         1 M----KYNQYSYIGTSVSQAEKELKELGF---QISSQKTNKANLATFVSQVYFHNPdkdd---vfkSIIADSQTDLATFL 70  Streptococcus m...
B9DVM1         1 M----RYNQFSYIKTDGQVAKKELENLGF---HFPISNKPKEIFRSFLNTYFFQSSdkdy---qiaSFIADFETDLLSFF 70  Streptococcus u...
Q8DXW0         1 M----RYNQFSYIPTKPNEAFEELKGLGF---PLNKKNSDKANLEAFLRHSFLNQTdtdy---alsLLIVDAKTDALTFF 70  Streptococcus a...
Q8DQ87         1 M----RFNQYSYINFPKENVLSELKKCGF---DLQNTANHKDSLETFLRRFFFTYQdtny---plsILAADKKTDLLTFF 70  Streptococcus p...
Q5M2X3         1 M----KFNQFSYIPVSPETAYQELRSLGF---EVSLDASAKANFESFVRKYFLFFEdtdl---alkNWIADPETDLLSFF 70  Streptococcus t...
WP_011921783   1 M----RFNQFSFIKKETSVYLQELDTLGF---QLIPDASSKTNLETFVRKCHFLTAntdf---alsNMIAEWDTDLLTFF 70  Streptococcus suis

1LNS_A        64 KSS-IELDWEIFWNIALQLLDFVPNFDFEIGKAFEYAKNSNLPQIEAE-MTTENIISAFYYLLCTRRKTGMILVEHWVSE 141 Lactococcus lactis
Q9CE01        64 KSS-IELDWEIFWNITLQLLDFVPNFDFEIGKATEFAKKLNLPQRDVE-MTTETIISAFYYLLCSRRKSGMILVEHWVSE 141 Lactococcus lac...
WP_014024201  64 SSE-QALTWNIFWTVSLQLLGFVPNFEFQVDQAKEFAQSVNLPMVDEEaLNSENLISALYLLLCSRRKNGMTLVEHWVSE 142 Lactococcus gar...
Q04E49        78 ERDfQSISAEDFYLVIDQLLDFNLGLEIDFGSGKQFLIDSGQQVLSAVkIDSTNLADFLFNALILRSANGLSLIDNLVSD 157 Oenococcus oeni...
Q8DVS2        71 HSD-RELTEEIFYTIALQLLEFTPYIDFD--EAKTFIKHSHFPII----FQPKHFLLNFYQLLGTRTKNGMTLIDKLVSQ 143 Streptococcus m...
B9DVM1        71 NAD-KPLTKEIFDMVSLQLLGFIPGFDFE--NLKEFTSQIAFPVP----FNENDLFASIHHLLGTRHKNGMLLIDDLISK 143 Streptococcus u...
Q8DXW0        71 KSN-SDLTLENLQWIYLQLLGFIPFVDFK--DPKAFLQDINFPVS----Y--DNIFQSLHHLLACRGKSGNTLIDQLVAD 141 Streptococcus a...
Q8DQ87        71 QSE-DELTADIFYTVAFQLLGFSYLVDFE--DSDVFRKETGFPII----Y--GDLIENLYQLLNTRTKKGNTLIDQLVSD 141 Streptococcus p...
Q5M2X3        71 QSD-RPLTAEVFGLVALQLLGFVPNVDFT--DSVAFLEKMAFPIA----FDGS--LNNLHQLLATRTQSGNTLIDQLVAQ 141 Streptococcus t...
WP_011921783  71 QSD-RELTDQIFYQVAFQLLGFVPGMDYT--DVMDFVEKSNFPIV----Y--GDIIDNLYQLLNTRTKSGNTLIDQLVSD 141 Streptococcus suis

1LNS_A       142 GL 143 Lactococcus lactis
Q9CE01       142 GL 143 Lactococcus lactis subsp. lactis Il1403
WP_014024201 143 GL 144 Lactococcus garvieae
Q04E49       158 GF 159 Oenococcus oeni PSU-1
Q8DVS2       144 GF 145 Streptococcus mutans UA159
B9DVM1       144 GF 145 Streptococcus uberis 0140J
Q8DXW0       142 GL 143 Streptococcus agalactiae 2603V/R
Q8DQ87       142 GL 143 Streptococcus pneumoniae R6
Q5M2X3       142 DL 143 Streptococcus thermophilus LMG 18311
WP_011921783 142 Dl 143 Streptococcus suis
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap