Conserved Protein Domain Family
SANTA

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pfam09133: SANTA 
SANTA (SANT Associated)
The SANTA domain (SANT Associated domain) is approximately 90 amino acids in length and is conserved in Eukaryota. It is sometimes found in association with the SANT domain (pfam00249, also known as Myb-like DNA-binding domain) implying a putative function in regulating chromatin remodelling. Sequence analysis has showed that the SANTA domain is likely to form four central beta-sheets with three flanking alpha- helixes. Many conserved hydrophobic residues are present which implying a possible role in protein-protein interactions.
Statistics
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PSSM-Id: 401175
View PSSM: pfam09133
Aligned: 35 rows
Threshold Bit Score: 86.5396
Threshold Setting Gi: 47230121
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001747655  200 TALLDWWVFFss-----sgVRIRGYIPDTTRQQlgpgtsstmMRTTIIVKRVESRLVMSKSGSQYKLTGNFVEEECRQAG 274  Monosiga brev...
XP_003099736   20 VRLKLWSIQFdg------sIRLEGFVRNEDGTMmq------kVCSEPICKRMTATMLFDISGRFFELAGQIDREYQQKKG 87   Caenorhabditi...
O44548         20 IRLNLWSMKFna-----tsFKLEGFVRNEEGTMmq------kVCSEFICRRFTSTLLFDVSGRFFDLVGQIDREYQQKMG 88   Caenorhabditi...
F4KCE9         19 VVLRDWWLIKcpkefegkqFGVAGF-EESVETRam-----rvFTSSPITKALDVFTLLASDGIYITLRGFLNKERVLKNG 92   thale cress
XP_019068874   17 VYLYDWWLIKvetgdgskrLGVGGF--TAKERPdg-----rvFHSTTIAKRHDTTTLVTEDGITILLSGFINRCRTLQNG 89   tomato
XP_006586752   21 IFLHEWWLVKqr-----kgLAVGGL-ASVEIADre-----rvFLSSVIVGREETNVLHSEDGITILFRGFINTSRSSQNG 89   soybean
XP_009102713   69 VSLSDWWLTKkan---etgLGVSGF--ESKGGPev-----rlFSSATISTRHDSTTLETSDGLTVSISGFINRSRSFQNG 138  field mustard
KQJ85163       65 VTLWDWWLVRvege--qrkIAVSGFTQRDDA-----------FTSAPIAKCHGPLTLEDEDGVVVLIYGSVSLSRMRENG 131  stiff brome
Q0JM77         30 VELDDWWLERvege--egkVRVVGS--NTTTSRag-----rrFTSASIKTRHASGDLETEDGIIIMIARPPNISKMHLNG 100  Japanese rice
XP_002529771   37 VLLHDWWLLKads----rrISVAGL--ASRQRLgn-----rvFLSAPISRRIDATTLETIDGITITISGFINRSKTHQNG 105  castor bean
XP_001747655  275 VDDRLIDAFARcnngkgGFPSNWRTV 300  Monosiga brevicollis MX1
XP_003099736   88 MPSRVIDEFTN------GFPENWGFL 107  Caenorhabditis remanei
O44548         89 MPSRIIDEFSN------GIPENWADL 108  Caenorhabditis elegans
F4KCE9         93 FNPEISREFIF------GFPPCWERV 112  thale cress
XP_019068874   90 FSSEVCKQFLL------GFPYNWEES 109  tomato
XP_006586752   90 VPFQVCQHFLV------GFPHDWKKY 109  soybean
XP_009102713  139 FSSEDCNRFLL------GFPYHWKDY 158  field mustard
KQJ85163      132 FSPQICEKFMI------GFPYWWESW 151  stiff brome
Q0JM77        101 FPDEVSKHFSL------GFPVQWENI 120  Japanese rice
XP_002529771  106 ISFLVCNQFKL------GFPYHWEEC 125  castor bean
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