4QHB,7ZGN


Conserved Protein Domain Family
N-glycanase_C
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pfam09113: N-glycanase_C (This model is not part of the current CDD release)
Peptide-N-glycosidase F, C terminal
Members of this family adopt an eight-stranded antiparallel beta jelly roll configuration, with the beta strands arranged into two sheets. They are similar in topology to many viral capsid proteins, as well as lectins and several glucanases. The domain allows the protein to bind sugars and catalyzes the complete removal of N-linked oligosaccharide chains from glycoproteins.
Links
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Statistics
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PSSM-Id: 518696
Aligned: 24 rows
Threshold Bit Score: 139.401
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4QHB_A         233 TYPDIFSRKD-VVX---DFDXPKAAKNVRLKYIVTGHG--GHSGGDEFVEKRNIVSVDG----KEVLNFIPWRDDCASFR 302 Phocaeicola v...
jgi:Fluta_0311 251 NYNAAATDAVgTTVktiNFTTTQTIYGAKFYLITSNHG--AGNNGEEYVRRVHNVTFDG----NQVLTYTPGGKSCEPYR 324
Q9RYI7         491 AYNTRQ-----APV---TFERPAWAKKVEFSTLVTGHGfnDSKSCAEFCNTVHHVTVNGn---DFTLSSPVTDNPLGCFE 559 Deinococcus r...
XP_001747879   531 TYNTRDALQIaAPA---QL--PAGQRRAYLTAIITGHG------SMEFVPSNHTFLVNGha-fSVAFLE--PLDQMACAR 596
XP_015213582   546 NYNKKY-----QPV---NFTVPTAVRKVEIYAVITGHGs-DDNGCGEFCVTSHHFLINSkfnhSKVFEK--AGTAFGCAE 614
XP_003450330   518 NYNKRY-----QPI---KFTVPASTKKVELYAVITGHGs-DENGCGEFCVTSHHFVINAahnnTHVFDS--AGTALGCAM 586
7_pfamImport     1 NYNKRL-----EPV---RFSVPAPAQKVELYAVITAHGs-DDRSCGEFCVTSHHFLLNGvfnnTLMFDS--AGSPLGCTT 69 
1_pfamImport     1 NYNKRH-----RPV---KVSVPASTKKVELYAVITAHGy-DENHCGEFCVTSHHFLINGvfnnTLTFDS--AGTPLDCTL 69 
XP_002110158   502 NYNKKY-----KPI---HFNMTSKTKKVKLVAVITGHGs-DNNNCAEFCVTSHHFMVNEkhanVRTFSN--AGNSLGCAE 570
8_pfamImport     1 TYPDIFARRA-VTT---DFTLPRDARNVELKYIVTGHG--GHSGGDEFVQKQNIVSVDG----KEALNFIPWRDDCASFR 70 

4QHB_A         303 RFN----------PAT-GVWLiprvaayigdkgyttkeieeplassdLSRSNWCPGSDVXPEEAVIgDLSAG----KHSF 367 Phocaeicola v...
jgi:Fluta_0311 325 QFNtqgngiygqsPQS-ASWW--------------------------TGWNNWCPGDTIAIRKINLgTLAPG----NHTF 373
Q9RYI7         560 QVKdg------vvPNQsGTWV--------------------------YGRNNWCPGQGVKLWNSDLsAAATGp--gPHTL 605 Deinococcus r...
XP_001747879   597 RAAeg------vePNGhGAIW--------------------------FGRDGWCNGMKVDSWLADVtTAIAD----SNTI 640
XP_015213582   615 AVKeg------vvPNEhGTWL--------------------------YGRGGWCDGLQVTPWRIDItSQLNMn--gSNTI 660
XP_003450330   587 RVKeg------avPNEhGTWL--------------------------YGRGGWCDGLQVNPWRVDVtKQLNMnrseSNTV 634
7_pfamImport    70 QVKeg------avPNEyGTWL--------------------------YGRGGWCDGLQVDPWRVDVtKQLNMs--ePNSI 115
1_pfamImport    70 RVKeg------avPNEyGTWL--------------------------YGRAGWCDGLQVDPWRTDVtKQLNMsqfeSNTV 117
XP_002110158   571 RVLqg------vtPNEhGTWL--------------------------YGRDGWCDGQEIKPWIVDItNQLSTk--sVNTI 616
8_pfamImport    71 RFN----------PGT-GVWLvkrlasyidgegyamkeveeplgssdLSRSNWCPGSDVVPETAALgDLKAG----THTF 135

4QHB_A         368 KV----------SIPEAQQvDGNKLNHWLVSAYLV 392 Phocaeicola vulgatus ATCC 8482
jgi:Fluta_0311 374 KI----------AVPAAQF--AGQDGNFPLSLYLQ 396
Q9RYI7         606 TYkalv--dgqdHLSKLED-GAERDASIHMTSWLV 637 Deinococcus radiodurans
XP_001747879   641 EYqafqydtgrwVQPNSTD------GYMRVTSNLV 669
XP_015213582   661 LYfglf--dgkdPNPARDP------GYIIMYSYLV 687
XP_003450330   635 VYfglf--ngrdPNPAQQP------GYIIMTSSLV 661
7_pfamImport   116 IYfglf--egrdPNPSKDP------GYIIMSSFLV 142
1_pfamImport   118 VYfglf--qgkdPNPSKEP------GYIIMSSFLV 144
XP_002110158   617 TYhgyy--nhtdPHPTSKP------GYIIMYSFLS 643
8_pfamImport   136 TV----------SIPEAQPvKGNELNHWLVSAYLV 160
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