Conserved Protein Domain Family
SNN_transmemb

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pfam09049: SNN_transmemb (490087 is an unknown moldel)
Stannin transmembrane
Members of this family consist of a single highly hydrophobic transmembrane helix that transverses the lipid bilayer at a 20 degree angle with respect to the membrane normal. They contain a conserved cysteine residue (Cys32) that, together with Cys34 found in the stannin unstructured linker domain, constitutes the putative trimethyltin-binding site that resides at the end of the transmembrane domain close to the lipid/solvent interface.
Statistics
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PSSM-Id: 490087
Aligned: 2 rows
Threshold Bit Score: 37.2656
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_012825431  2 SIMDHNPTTGVVTVIVILIAIAALGALILGCW 33 
1_pfamImport  1 SIMDHNPTTGVVTVIVILIAIAALGALILGCW 32 
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