6CRO


Conserved Protein Domain Family
Cro
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pfam09048: Cro (This model is not part of the current CDD release)
Cro
Members of this family are involved in the repression of transcription by binding as a homodimer to palindromic DNA operator sites in phage lambda: they repress genes expressed in early phage development and are necessary for the late stage of lytic growth. These proteins have a secondary structure consisting of three alpha-helices and three beta-sheets, and dimerize through interactions between the two antiparallel beta-strands.
Links
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Statistics
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PSSM-Id: 518655
Aligned: 5 rows
Threshold Bit Score: 95.6636
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6CRO_A        2 Q-RITLKDYAMRFGQTKTAKDLGVYQSAINKAIHAGRKIFLTINADGSVYAEEVKPFPS 59  Lambdavirus lambda
1_pfamImport  2 E-RIPLTTFATEVGQHKTAEMLGVRQSAISKAILKKRNIYVIKKQDGTVEAEEVKTFPS 59 
Q87Y09        2 E-RISLSDFVTKIGQARVARALGCKPASIAKALKARRNIEVSVDTDGSCIAQEVRPFPS 59  Pseudomonas syringae pv. tomato
Q32F75        4 K-KETLADYVYRFGQKKAAKDFGVAQSAISKALLVGREIYVKTFDDGTVEAEEVRPFPA 61  Shigella dysenteriae Sd197
P03040        2 EqRITLKDYAMRFGQTKTAKDLGVYQSAINKAIHAGRKIFLTINADGSVYAEEVKPFPS 60  Escherichia phage Lambda
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