1N6J


Conserved Protein Domain Family
MEF2_binding

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pfam09047: MEF2_binding 
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MEF2 binding
The myocyte enhancer factor-2 (MEF2) binding domain, predominantly found in the calcineurin-binding protein CABIN 1, adopts an amphipathic alpha-helical structure, which allows it to bind a hydrophobic groove on the MEF2S domain, forming a triple-helical interaction. Interaction of this domain with MEF2 causes repression of transcription.
Statistics
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PSSM-Id: 370261
View PSSM: pfam09047
Aligned: 2 rows
Threshold Bit Score: 39.8347
Threshold Setting Gi: 39654239
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1N6J_G     1 TLLSPKGSISEETKQKLKSAILSAQSAANVRKESL 35 
KTG45535 203 TLLSPKGSISEETKQKLKNVILSSQSAANVKKDTL 237 common carp
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