2AVW


Conserved Protein Domain Family
Mac-1

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pfam09028: Mac-1 
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Mac 1
The bacterial protein Mac 1 adopts an alpha/beta fold, with 14 beta strands and 9 alpha helices. The N-terminal domain is made up predominantly of alpha helices, whereas the C-terminal domain consists predominantly of beta sheets. Mac 1 blocks polymorphonuclear opsonophagocytosis, inhibits the production of reactive oxygen species and contains IgG endopeptidase activity.
Statistics
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PSSM-Id: 401100
View PSSM: pfam09028
Aligned: 2 rows
Threshold Bit Score: 528.599
Threshold Setting Gi: 90108758
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2AVW_C           2 D-----SFSANQEIRYSEV------TPYHVTS------VWTKGVTPPANFTQGEDV---------FHAPYVANQGWYDIT 55   Streptococcu...
bgi:05SSU0545  103 RndtevTTSEQNQIEVTETkeilnqTSYQTESgeqrqiIWAHGITPPAMEQSGGFVkekygdylnYTAPFEAGKGYYDTN 182  Streptococcu...
2AVW_C          56 KTFNGK--DDLLAGAATAGNMLHWWFDQNKDQIKRYLEEhpekQKINFNGEQMF---DVKEAIDTKNHQLDSKLFEYFKE 130  Streptococcu...
bgi:05SSU0545  183 KSLNASfiDLNLCFAAVSSNMVHWWLEQNSSYVERYLKE----KKGTVNVEENYaitDLRRYINSFQNQQNSRVFDMFKT 258  Streptococcu...
2AVW_C         131 kafpYLSTKHLGVFPDHVIDMFINGYR------LSLTNHGPTPvkegskDPRGGIFDAVFtrgdQSKLLTSRhdFKEKNL 204  Streptococcu...
bgi:05SSU0545  259 ----YYGYRTNGFVSDALVDLFINGYKpkaqggVNLEDSQLVP------DSRGGFFYDVF----KEKKLTNR--IFSGSY 322  Streptococcu...
2AVW_C         205 KEISDLIKKELTEGKALGLSH---TYAnvriNHVINLWGADFDSNGNLKAIYVTDS-DSNASIGMKKYFVGVNSAGKVAI 280  Streptococcu...
bgi:05SSU0545  323 ERFGEDVRTVLESKGLLGLTYrtlGYA----THIVTVWGAEYDNQGKIKAVYITDSdDQQEQIGLKRMGITRDASGNPRL 398  Streptococcu...
2AVW_C         281 SaKEIKEDNIGAQVLGLFTLSTGQDSW 307  Streptococcus pyogenes MGAS5005
bgi:05SSU0545  399 N-NHMKNNSAGALLDYVHTIRLGQDLW 424  Streptococcus suis 05ZYH33
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