4OK9,4H4L


Conserved Protein Domain Family
HutP
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pfam09021: HutP (This model is not part of the current CDD release)
HutP
The HutP protein family regulates the expression of Bacillus 'hut' structural genes by an anti-termination complex, which recognises three UAG triplet units, separated by four non-conserved nucleotides on the RNA terminator region. L-histidine and Mg2+ ions are also required. These proteins exhibit the structural elements of alpha/beta proteins, arranged in the order: alpha-alpha-beta-alpha-alpha-beta-beta-beta in the primary structure, and the four antiparallel beta-strands form a beta-sheet in the order beta1-beta2-beta3-beta4, with two alpha-helices each on the front (alpha1 and alpha2) and at the back (alpha3 and alpha4) of the beta-sheet.
Links
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Statistics
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PSSM-Id: 518639
Aligned: 51 rows
Threshold Bit Score: 120.309
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4OK9_A           9 IGRQALLLAMLDEGEEgAIL-DELRASNWRYCQGRVGAME-----PQKIVAAIETAAKRHEVVDGSlYRDMHALYHAILE 82  Geobacillus t...
WP_013277136   128 pesSAIYLSMTRSREYeNYWlDKINGYGYKAAITQTGANAed--lPIKLRESATVAAIARKVIKER-AKEKVAVSNAVRD 204 Acetohalobium...
5_pfamImport     1 IGRVAVLLAATTSKAEeEYLkEQIKKMGWKAVATEVGGLAgn--iSGKLTRALVGAALNGNVVKKT-GTEMHALMHASME 77 
jgi:Tlie_0742   51 VGRAALLLALTTDAEEeQNVkKQIVATGWRAVATEVGGLAge--lPQKITRALVGAALNAGVVEKK-CNEMHALMHAAVE 127
jgi:Amico_0721  52 VGRAALLLASTTTPDSeNELkRELLQNGWRSVATEVGGLAgd--lPQKITRALVGASLNAGVVEKT-RNEMHALMHAAVE 128
WP_006717401    14 LEREALFLVLTDTREKeNEVkQKLIAENLNCAVTEIGGTVatlqpTGKLTHSVISAALNTGVIKKD-PKAIHAVVHATLE 92  Desulfitobact...
CDA48341        17 LCRMAVLLAMTVDQKMeRDLiLQLQKRGIKSAATTVAGFGis--sQSNIIRSVVNLCLNTNIIERK-REHVHPVAHCVLE 93 
WP_015327721    20 LGKMATMLAMV-KDKAdDKLvNTFMEEGYNAVITRAGGKGee--lKNKVLRNALGAAVKGNVIGDD-IQNRRVLTRCVER 95  Halobacteroid...
WP_015923614    20 LGKVATILAIV-DDQYdDDIiESLKKEGYKAVITRAGGKGee--lKNKILRNCLGAAIKGGVITES-IQDQRVLTRCVER 95  Halothermothr...
WP_013406622    20 IGKVAVLLSMV-NDEHdKNIiEAYKNEGYEAVITRAGGKGsk--lKDKVLRNCLGAAIKGGVITES-VQDQRILTRCVER 95  Halanaerobium...

4OK9_A          83 AVHGV-TRGQVELGdllrtAGLRFAVVRgtpyeqpkEGEWIAVALYGTIGAPVRg-lEHEAVGLGIN 147 Geobacillus thermodenitrif...
WP_013277136   205 AYNQL-NLINPGLG-----GGFKVAIVR--------GEGKVAVSAFGKFGHALVdgpEQIALGtsii 257 Acetohalobium arabaticum
5_pfamImport    78 AINSFlPMCLLEAS-----VGAKLAIVR--------SKRWIGVAIMGDSAYHATa--HHDRCGLGIM 129
jgi:Tlie_0742  128 ALNGFiSMSMLEAS-----IGAKIGIVR--------NDQWIAVAVLGDMAYHAVa--HHERCGLGVM 179
jgi:Amico_0721 129 ALEGFlTVGMLEAS-----VGAKIAIVR--------NDRWIAVAVMGDTAYHAVa--HHERCGLGVM 180
WP_006717401    93 ATNSI-FVHTNSNAs----FALKIAMVT--------DNDWIAIAIFGRTSVNILs--EHCRVGLGYM 144 Desulfitobacterium metalli...
CDA48341        94 VTQSTrASDAIGQN-----FCFKAAVAR--------KGNHFALSFYGNLAMHELs--GHKTIGVGFq 145
WP_015327721    96 ALTGL-NGPMSSISg----AGIKIGIVK--------HGVHLAVAIHGKIGIPGLe-vDHEISGLGVH 148 Halobacteroides halobius
WP_015923614    96 AMVDF-NTPMLSISg----AGIKIGIAS--------KGPHLAVALYGKLGIPGLd-vDHEISGMGIH 148 Halothermothrix orenii
WP_013406622    96 AMIDF-EKPLSGISg----AGIKIGIVS--------KAPHLAVALYGKLGIPGLd-vDHEISGMGIH 148 Halanaerobium hydrogenifor...
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