Conserved Protein Domain Family
EcoRII-C

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pfam09019: EcoRII-C 
EcoRII C terminal
The C-terminal catalytic domain of the Restriction Endonuclease EcoRII has a restriction endonuclease-like fold with a central five-stranded mixed beta-sheet surrounded on both sides by alpha-helices. It cleaves DNA specifically at single 5' CCWGG sites.
Statistics
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PSSM-Id: 401096
View PSSM: pfam09019
Aligned: 8 rows
Threshold Bit Score: 274.265
Threshold Setting Gi: 81784547
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8G4B6          235 FKLYERAVIQHDYDAAPFvsdgvIDVDSFTSFYTSVRNRRMSRAGKVLEIHIAHILDARGI----EYEAQA---KTENGK 307 Bifidobacter...
jgi:Glov_0294   231 FRTLERHIIGDRLQVGFV-----DDVDGFVTYSLSVQNRRKSRAGSSLENHLEVIFNAQGI----QYTRTP---VTENNE 298 Geobacter lo...
Q727L4          225 FRMFERHLVAQRLREGFG-----EDVDAFTGYALSVLNRRKARAGKALENHVEQVLKDWGV----PYTREC---RTENNS 292 Desulfovibri...
Q0AK57          222 FRALERGIVGDRLMLGFLdsrgePDVDAFLKFSLSVQNRRKSRAGHALMNHFSKILRAFEI----PFTPEA---TTEKKG 294 Maricaulis m...
Q9JZ51          218 FSIFEKREF-EIIKSKIT------DLDSFINFAHSFTNRRKARAGKSLELHLSRIFDEFSL----KFETQA---KTEGKK 283 Neisseria me...
WP_011930843    233 FLSVEEAVYLPRIRQGFS------AIGDFLSLAQTILQSRKTRSGTSLELHVREIMTEEGLladtSFTYRP---VIENGK 303 Acidiphilium...
wugsc:CKO_03469 227 FLLVEEMHVLGIVQSGFG------SVNEFIALANSVSNRRKSRAGKSLELHLEQLFNEHGLk---TFETQA---VTEGNK 294 Citrobacter ...
jgi:Hhal_0412   231 FRAYEREIVQERLERGFA-----GDVDEFIRFSLSVHNRRKSRVGHAFENHLTELFERHGL----RFEKGGvnrVTENKS 301 Halorhodospi...
Q8G4B6          308 KPDFLFPSQAAYE------DPAFPEEQLRMLASKTSIKDRFRQVADEANRIRDKHLFTLTPGdVTHPKLAQLDELHIHLV 381 Bifidobacter...
jgi:Glov_0294   299 KPDFIFPDIIHYR------DPDFDVSKLTMLGVKSTCKDRWRQILSEADRIKSKHLLTLEPG-ISENQTNQMKRSNLQLV 371 Geobacter lo...
Q727L4          293 KPDFIFPGCSEYH------QTNFPQDQLRMLAVKSTCKDRWRQVLAEAARVSRKHLLTLEPG-ISVQQTTEMVDHAVQLV 365 Desulfovibri...
Q0AK57          295 AADFLFPSEAAYA------DPGFPSANLRMVAAKTSCKDRWRQVLAEADRIKPKHLLTLQPK-ISLAQTTEMTDQGIILT 367 Maricaulis m...
Q9JZ51          284 KPDFLFPGSEEYHamdesgNFIFQTEKLTMLGSKTTCKDRWRQVLNEADRIPHKHLFTLQEG-ISDTQIQEMSDENLTLV 362 Neisseria me...
WP_011930843    304 RPDFLFPSKAAYD------NPAFPAERLRMLAAKTTCKDRWRQVLNEADRIATKHLLTLQEG-VSEGQFREMSEAGVRLV 376 Acidiphilium...
wugsc:CKO_03469 295 KPDFLFPSAQAYH------DEAFPEQKLRMLAVKTTCKDRWRQILNEADRIQDIYLFTLQEG-VSVAQFQEMQQERVRLV 367 Citrobacter ...
jgi:Hhal_0412   302 KPDFLFPGFTEYH------DPQFPNSRLFLLGAKTTCKERWRQVLAEGERLKRKHLATLEPG-ISRTHTDEMSAHGLQLV 374 Halorhodospi...
Q8G4B6          382 MPKVVKESYDDLIQGETMTFSRFI 405 Bifidobacterium longum
jgi:Glov_0294   372 VPSALQRTYKTEQQTWLLTFDDFI 395 Geobacter lovleyi SZ
Q727L4          366 IPRGIQSSFQDAQREELISLGEFV 389 Desulfovibrio vulgaris str. Hildenborough
Q0AK57          368 LPSPIHSSFQDDQRASLLTVADLL 391 Maricaulis maris MCS10
Q9JZ51          363 VPKESVKTFGTFGKTHVLTLENFI 386 Neisseria meningitidis serogroup B
WP_011930843    377 VPAELHRSYPASVRPHLVTFENFI 400 Acidiphilium cryptum
wugsc:CKO_03469 368 VPSSLHDKYPKAIREYLISLETFI 391 Citrobacter koseri ATCC BAA-895
jgi:Hhal_0412   375 VPLPIHATYSETQRMKIMGIQDFI 398 Halorhodospira halophila SL1
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