4JHS,1C1Z


Conserved Protein Domain Family
Sushi_2

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pfam09014: Sushi_2 
Beta-2-glycoprotein-1 fifth domain
The fifth domain of beta-2-glycoprotein-1 (b2GP-1) is composed of four well-defined anti-parallel beta-strands and two short alpha-helices, as well as a long highly flexible loop. It plays an important role in the binding of b2GP-1 to negatively charged compounds and subsequent capture for binding of anti-b2GP-1 antibodies.
Statistics
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PSSM-Id: 401094
View PSSM: pfam09014
Aligned: 25 rows
Threshold Bit Score: 137.041
Threshold Setting Gi: 1540401412
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4JHS_A        96 KASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCK--NKEKKCSYTEDAQCIDGTIEVPKCFK-EHSSLA---F 169
5_pfamImport   1 KAPCPVGIHRGRILYREQKLWIKELKPKRILHSELISVYCM--NTERKCGYAVSTQCIDGNLKIPECFE-EPSLNTynlH 77 
4_pfamImport   1 KAPCRVGLERARILYKEKKIWIEDLNPNRVLHNEIISFYCM--DMDRQCGYAVSTQCIEGKLKIPECFElEPSAIHyklQ 78 
XP_004066257 263 RAPCTVGIKRGRIFYNARKIWIEDLKPNRVLHGEIVVFYCL--NRDEKCGYPVSSTCNDGTLPIPECFE-EPGKVEynlK 339 Japanese medaka
XP_003978255 263 RAPCTVGIKRGRIFYNSQKLWIADLKPNRVLHGEHVAFYCL--NKADRCGYPVASTCRDGNLPIPECFE-EPGKIEyniR 339 torafugu
XP_005807939 261 RAPCEVGIKRGRIFYNARKIWIEDLRPNRVLHGEHVAFYCK--DKAEKCGYPVASTCNDGNLPIPDCYE-QPGKIEynlR 337 southern platyfish
AAN65634     270 RARCPVPAQRSRVIVGGVKRWPYDLTDGVVAHGENVTFFCK--HPEKLCSFTATEVCVDGELKAPSCYL-DPTWLQfklY 346 zebrafish
XP_014341694 264 KASCIIPIKRGRIYYNAEKIWIEKLPEKRVQHAEEVAFYCK--NKEKKCGYPVLAQCINGTIEVPSCFK-EPGRVEyqiH 340 coelacanth
XP_006635542 264 RASCIIDIRRGRIFYSSKKIWIEDLPEKRVQHSEHVAFYCK--NEEKKCGYPVVTQCVDGTLNIPECFK-EPGAVEyklN 340 spotted gar
XP_006012854 258 RSRCKIPVKRSRFIYYDSKVWVQEVVDGVVQHLDTVSFYCRlsGADFTCSYTVQSQCFDGTLPLPDCYE-EPTWLQymlF 336 coelacanth
4JHS_A       170 WKTDASDVKPC 180
5_pfamImport  78 YDTLPSEITQC 88 
4_pfamImport  79 SSSLPSEMKQC 89 
XP_004066257 340 SKSLPSEIRMC 350 Japanese medaka
XP_003978255 340 AKTLPSEIEMC 350 torafugu
XP_005807939 338 SKNLPSEIRAC 348 southern platyfish
AAN65634     347 PHRLVSEIDAC 357 zebrafish
XP_014341694 341 SSSLPSEIKQC 351 coelacanth
XP_006635542 341 YKSLPSEIKMC 351 spotted gar
XP_006012854 337 PKRLVSEITPC 347 coelacanth
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