1HUF


Conserved Protein Domain Family
YopH_N

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pfam09013: YopH_N 
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YopH, N-terminal
The N-terminal domain of YopH is a compact structure composed of four alpha-helices and two beta-hairpins. Helices alpha-1 and alpha-3 are parallel to each other and antiparallel to helices alpha-2 and alpha-4. This domain targets YopH for secretion from the bacterium and translocation into eukaryotic cells, and has phosphotyrosyl peptide-binding activity, allowing for recognition of p130Cas and paxillin.
Statistics
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PSSM-Id: 401093
View PSSM: pfam09013
Aligned: 2 rows
Threshold Bit Score: 143.454
Threshold Setting Gi: 57015232
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1HUF_A   8 LSLsdLHRQVSRLVqqeSGDCTGKLrgnVAAN--KETTFQGLTiasgareSEKVFAQTVLSHVANVVLTQEDTAKLLQst 85  Yersinia pestis
P69978   7 QSL--INQQITQVG---HGGQAGRL---TETNplTENSHQIST-------AEKAFANEVLEHVKNTALSRHDIACLLP-- 69  Yersinia pestis
1HUF_A  86 vkhNLNNYDLRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQ 128 Yersinia pestis
P69978  70 ---RVSNLELKQGKAGEVIVTGLRTEQLSLSDAKLLLEAAMRQ 109 Yersinia pestis
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