6K4Y


Conserved Protein Domain Family
AsiA

?
pfam09010: AsiA 
Click on image for an interactive view with Cn3D
Anti-Sigma Factor A
Anti-sigma factor A is a transcriptional inhibitor that inhibits sigma 70-directed transcription by weakening its interaction with the core of the host's RNA polymerase. It is an all-helical protein, composed of six helical segments and intervening loops and turns, as well as a helix-turn-helix DNA binding motif, although neither free anti-sigma factor nor anti-sigma factor bound to sigma-70 has been shown to interact directly with DNA. In solution, the protein forms a symmetric dimer of small (10.59 kDa) protomers, which are composed of helix and coil regions and are devoid of beta-strand/sheet secondary structural elements.
Statistics
?
PSSM-Id: 401090
View PSSM: pfam09010
Aligned: 2 rows
Threshold Bit Score: 118.965
Threshold Setting Gi: 1720272825
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6K4Y_I  22 NKNIDTVREIITVASILIKFSREDIVENRANFIAFLNEIGV-THEGRKLNQNSFRKIVSELTQEDKKTLIDEFNEGF--- 97  Escherichia virus T4
Q6WHK8  10 KSTPELALDIAAYASLLVKMGYDECVTNQKLFVEMCNEAGFrTTTGKEFTQMSFRQMFARLPQGTKREVRESFSWGNvpq 89  Vibrio phage KVP40
6K4Y_I  98 -EGVY 101 Escherichia virus T4
Q6WHK8  90 gESIL 94  Vibrio phage KVP40
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap