1IKQ


Conserved Protein Domain Family
Exotox-A_cataly
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pfam09009: Exotox-A_cataly 
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Exotoxin A catalytic
Members of this family, which are found in prokaryotic exotoxin A, catalyze the transfer of ADP ribose from nicotinamide adenine dinucleotide (NAD) to elongation factor-2 in eukaryotic cells, with subsequent inhibition of protein synthesis.
Links
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Statistics
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PSSM-Id: 430368
Aligned: 2 rows
Threshold Bit Score: 324.301
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1IKQ_A   422 LLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRARSQDLDAIWRGFYIAGDPALAYGYAQDQEPDArgrirNGALLRV 501 Pseudomonas aeruginosa
KMN83734 440 LQATHQRLLDQGYVFAGYHGGSLAAATSIVTGGITRRSQELQPIWRGLYIAGNPEVAYGYALDNDSGA-----TGIMMRV 514

1IKQ_A   502 YVPRSSLPGFYRTSLTLAAPEAA-GEVERLIGHPLPLR----LDAITGPEEEGGRLETILGWPLAERTVVIPSAIPTDpr 576 Pseudomonas aeruginosa
KMN83734 515 YVPRAALSRLFRTSQPLNDEAAAlREISRLLGRNVTLNsvlgYESITGPQDPGEPDETILGWDLAEHAVAIPSMIQGN-- 592

1IKQ_A   577 nvgGDLDPSSIPDKEQA 593 Pseudomonas aeruginosa
KMN83734 593 ---NSVRPINVPDYEKK 606
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