1YTV


Conserved Protein Domain Family
V1R_C
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pfam08983: V1R_C (This model is not part of the current CDD release)
Vasopressin V1 receptor, C-terminal
This is the conserved C-terminal domain of Vasopressin V1a/b receptors (V1R), which is involved in receptor trafficking and facilitates the interaction between the intracellular loops of the receptor, the G proteins and coupling to phospholipase C. This domain is unstructured and may reflect its conformational plasticity that may be necessary for proper function of V1R.
Links
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Statistics
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PSSM-Id: 518614
Aligned: 8 rows
Threshold Bit Score: 54.4995
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1YTV_M        38 KFNKEDTDSM--SRRQTFYSN--NRSPTNSTGMWKD---------SPKSSKSIKFIPVST 84  human
XP_003500835 377 KLAKDDSDSM--SRGQTSHSN--NRSPTNSTGTWKD---------SPKSSRSIRFIPVST 423
XP_002931664 363 TFSKEDSDSS--TRRQTSFTRiqTRSPTNSTHTLKE---------SPKSSKSIKFLPIQT 411
NP_001284605 338 TLHKEDSDSS--IRRNTLLSKltSVRAKDGFDSWKD---------PCNSRKSSQSIGLDY 386
NP_001276729 359 QVHRQLSTSSltSRRTTLLTHa-CGSPTLRLSLNLSlr------aKPRPAGSLKDLE-QV 410
Q9WU02       359 RVHRQLSNSSlaSRRTTLLTHt-CGPSTLRLSLNLSlh------aKPKPAGSLKDLE-QV 410 house mouse
XP_003443973 365 DFKKEDSDSS--LRRTTLLTKmtNRSPTARTFFSRNpdafkgccaSPQCCRTPFPVKVFT 422
XP_001520677 376 KLTKEDSDSL--SRRQTSLTN--NRSPTNSSGAWRD---------SPRSSKSTKFIPVST 422 platypus
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