2FFS


Conserved Protein Domain Family
AtaL
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pfam08982: AtaL (This model is not part of the current CDD release)
Acetylaranotin biosynthesis cluster protein L
This entry includes acetylaranotin biosynthesis cluster protein L (AtaL) from Aspergillus terreus, which is a non-ribosomal peptide synthetase. It is required for the biosynthesis of the toxin acetylaranotin, which is a disulfide bridged cyclic dipeptide. There are a number of steps in the biosyntheis of this epipolythiodioxopiperazine toxin from two phenylananines, but the specific function of AtaL has yet to be determined. Homologues are also known from bacteria.
Links
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Statistics
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PSSM-Id: 518613
Aligned: 66 rows
Threshold Bit Score: 70.6944
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2FFS_A         16 DLPVLDRLQLWEGLVCRAREPQYFVVGLERFEILVDDGDRLHRRLYLPg-lVVEDeVVLKAPDSAHYSIkpsaeVAG--- 91  Pseudomonas ae...
WP_011763820   16 HTTRLTREELWFGLLCRAEDARPFLPGLESCRIVERSPNELVRDLHFGaavIRDR-VRFAELEWISFES-----EANaeh 89  Azoarcus olearius
Q5P4G1         16 LLTELNREEVWFGLLCRAEDARPFLPGLEACMIVERSESELVRELQFGsalIRDR-VTLMPMESIRFES-----ERTash 89  Aromatoleum ar...
WP_015433694   16 LASPLTREEVWFGLLCRVLDSRPFLPGLEACRILERTETEFRRELDFGsvvIRDQ-VTVQPMDWVRFES-----ERTeth 89  Azoarcus sp. K...
Q63ND6         16 AVPTLTRAQLWEGLVLRAEQPQLFVLGLDSCIVHERTETTLERELHYGnatVRDH-VTFTPNEQVRYDI-----HAAdge 89  Burkholderia p...
CAL63477       16 LIDTLTRAQLWRGLVLRAEAPKLFVPWLDECDLGERDGAVLPRTLRYNallIHDR-VTFTPQETVHYEV-----PAQgdi 89 
2_pfamImport   10 LIDSLTREQLWRGLVMRAESPGLFMPHLDDCRLSEKSLDSVRRELRYGelvIIDK-VTYLPQIQVLYEV-----PAQgei 83 
nioo:CFU_4290  29 LIDTLTREQLWRGLVMRAEQPMLFVEHLDDCLLADKSVQSVTRELRYGkviVKDV-VSYLPLLQVRYQV-----PKQqdi 102
1_pfamImport    7 HVKSLTRDQLWRGLMHRVEQPHVFLPHIDRVEILDRGEDFIERVMWFGdmeVRDR-IAFDDGVRFHYHT-----LASeah 80 
Q0K9V1         18 QLDPLTPDQLWQGLVLRAESPELFVLGLDRAEVVGRGDNWIDRVLHFGeasIHDH-VVFEPRRQVRYET-----AATaeh 91  Cupriavidus ne...

2FFS_A         92 --GSLDXTIEEPEPGsLFVRFAYCTR----Y--LQPLGDELPYD-AFVKQAYIAXDVETIATIRDRF 149 Pseudomonas aeruginosa PAO1
WP_011763820   90 agGSLTIRIEEPQPGaLFLRFIYATT----Lp-dVGGE-DAKYA-DIVRSAYHQSDLDTLKMIRMIA 149 Azoarcus olearius
Q5P4G1         90 pgGSLTITIEEPAEGvLVLRFRYLTT----LpeEAGSP-DRAYA-EYVKAAYHQSDLDTVRVIRMIA 150 Aromatoleum aromaticum EbN1
WP_015433694   90 agGTLTIAIEEPAPEtMVLRFEYRTT----LseHTSGD-DVAYA-EFVKSAYHASDLDTLRVIRMIA 150 Azoarcus sp. KH32C
Q63ND6         90 igGSLTMTIEERDDQqLFLRFEYRTT----LpvSNDSE-DARQTqEIVKEAYRTSDIDTVRLIREYA 151 Burkholderia pseudomallei
CAL63477       90 paSSLLVTIEEPQPGaLFVRFEYDSGk-------tDDDMDAFYD-EFRRSAYQEADIDTIRIIRQLA 148
2_pfamImport   84 ppSRMSMTIEEPQAEvLFVRFEYDDG----QpeDVTGE-EAFYD-NFRRSAYQEADIDTVRIIRELT 144
nioo:CFU_4290 103 ggSSLIMTIEEPEQEmLFVRFEYEDDaverQp-aAQAE-QEFYD-EFRRSAYQEADIDTIRVIRELA 166
1_pfamImport   81 agGHLTVSIEEPDAGeLFVRFCYETP----LaeRVEDGVDVG---SYLRSAWQQSDTEAMQKLRELA 140
Q0K9V1         92 agGTLTMAIETPGPGaLLLRFVYNTT----MpaVDASG-DDRYA-EIVKSAYHEADIDTVRKIREIA 152 Cupriavidus necator H16
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