2A9U


Conserved Protein Domain Family
USP8_dimer

?
pfam08969: USP8_dimer 
USP8 dimerization domain
This domain is predominantly found in the amino terminal region of Ubiquitin carboxyl-terminal hydrolase 8 (USP8). It forms a five helical bundle that dimerizes.
Statistics
?
PSSM-Id: 401063
View PSSM: pfam08969
Aligned: 21 rows
Threshold Bit Score: 100.811
Threshold Setting Gi: 242003056
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2A9U_A         8 SVPKELYLSSSLKDLNKKTEVK-P--EKISTksYVHSALKIFKTAEECRLDRDEERAYVLYXKYVTVY-NLIKKRPDFKQ 83  
XP_002422594   4 KENKSPFKFKSLEELKPHYDRLqLagKNPRD--LMHKLDKIFKTACEKMANEEIEDAYILIMKYLNVF-SFIQKSDDFKE 80   human body louse
ETN60849      12 NPPKPLHLGTHIDDLEKLYMKLpAdiRDRELdlICRSAKKLIEQSDRYYLEKDEEQAYVGYMRLMNLV-QTIRQNKEYAR 90   Anopheles darl...
EFN63967       2 SDAVNLH-KINYESINDLAEKAkInfNGKEPhnIYSRLPAMRQKSEAARKQGDDETAYIFLKRWLNSV-EWIKKTRDYKA 79   Florida carpen...
EFJ42270       9 TKPK-----SLVEHLSEQAPKR-PvnEIVSLdrYLMSAQLLLKQAADYRLIGDEEQLYVMLLRFASLVvETIPTHRDFRD 82   Volvox carteri...
XP_003289101   4 VNIKPLYISSSVQELVEKHCSIgDidKHYSLfnYLSTSNNLYKQAAQYKSEGDLEKSYIYSIRFCSLLlEKLPKHPEYTK 83   Dictyostelium ...
Q7QI15        10 GPIEP---HQRLQKLVADSQRV-SidPTMPInrYYRSGNQIVETADRSLREGNLEKAFTFYLRFVTIFvELILEHPGYRS 85   Anopheles gamb...
XP_002037360  11 GDVEP---QERMKHLSHCGNLI-EvdKNMPVtrYYRSGTEMLRMANVYLREGNHENAFILYLRYMTLFiEKIRQHPDYGS 86   Drosophila sec...
EDS38010      17 GTVEP---QERIRQLAALSNSV-EvdGNIPIkrYYRSGLEMVRMAAVYLAEGNVESAYILYMKFITLFvEKIKGHPEFKA 92   southern house...
EEZ97535      14 GLINP---QERLKHLINYSNAV-EvdFHIPPtrYYRSGLEMVRMANVYNSEGNYENAYVLYLKFMTLFlEKIRKHPDFNS 89   red flour beetle
2A9U_A        84 QQDYFHSILGPGNikKAV-EEAERLSESLKLRYEE 117 
XP_002422594  81 DSKYYKAMLGKQP--KDAlKIAENLHKNLSEYYSM 113  human body louse
ETN60849      91 KKQMVTKLLGTQAdfNRIfTKLNLLKTSLEERYRE 125  Anopheles darlingi
EFN63967      80 GKSIYSTNMTIDQinEVK-NILADLKQKLEIRYEH 113  Florida carpenter ant
EFJ42270      83 GNATYRG-LKKDLlvSFl-PELERLKASLRLKDRP 115  Volvox carteri f. nagariensis
XP_003289101  84 DVNKKSINDLKSKanQIl-SELESVKSVLDKGYIL 117  Dictyostelium purpureum
Q7QI15        86 VPPADKQ-LTKEKikKIm-PRAEEIRSKLLEKYTT 118  Anopheles gambiae str. PEST
XP_002037360  87 VKAEVRD-INRKIkdEIm-PTTEKLRAKLLTHYQR 119  Drosophila sechellia
EDS38010      93 VPADLKQ-QNVKKlkEVf-PVAEKLKERLLEKFRR 125  southern house mosquito
EEZ97535      90 VPVKMKA-INQAKlrEVl-PKAEKLKERLLEQYKE 122  red flour beetle
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap