1K4U


Conserved Protein Domain Family
p47_phox_C
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pfam08944: p47_phox_C (This model is not part of the current CDD release)
NADPH oxidase subunit p47Phox, C terminal domain
The C terminal domain of the phagocyte NADPH oxidase subunit p47Phox contains conserved PxxP motifs that allow binding to SH3 domains, with subsequent activation of the NADPH oxidase, and generation of superoxide, which plays a crucial role in host defence against microbial infection.
Links
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Statistics
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PSSM-Id: 518589
Aligned: 13 rows
Threshold Bit Score: 43.2796
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1K4U_P         1 SK----PQPAVPPRPSADLILNRCSESTKRKLASAV 32  human
XP_004840069 354 GK----PQPAVPPRPSAEVILHRCSESTKRKLASAV 385
XP_002817919 359 SK----PQPAVPPRPSADLILNRCSESTKRKLASAV 390
XP_006155068 357 AK----PQPAVPPRPSADVILHRCSESTKRKLASAV 388
XP_015223285 425 QG----GLPTVPPRPSRELILERCTEHTRKKVSIRS 456
3_pfamImport   2 KR----ETPVIPPRPSPELILERCTANTCKKVSIHR 33 
XP_019219177 376 KK----EAPVIPPRPSPELILERCTDNTRKKVSIHK 407
XP_021584279 360 AK----PQPAVPPRPSADLILHRCSESTKRKLASAV 391
F1M707       358 AK----PQPAVPPRPSSDLILHRCTESTKRKLTSAV 389 Norway rat
XP_007485758 354 PKppmqPQPAVPPRPSQDLILNRCSESTKRKLMTTV 389
NP_446186    358 AK----PQPAVPPRPSSDLILHRCTESTKRKLTSAV 389 Norway rat
NP_001027718 380 KR----EAPVIPPRPSPELILQRCSDNTRKKISIHk 411 torafugu
XP_058141940 358 AK----PQPAVPPRPSADLILHRCSESTKRKLASAV 389 nine-banded armadillo
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