1SF9


Conserved Protein Domain Family
DUF1811

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pfam08838: DUF1811 (This model is not part of the current CDD release)
Protein of unknown function (DUF1811)
This family includes uncharacterised proteins predominantly found in Firmicutes, including Uncharacterized protein YfhH from Bacillus subtilis and protein GK0453 from Geobacillus kaustophilus. GK0453 shows two small domains: an helix-turn-helix like motif is found in its N-terminal domain while an SH3-like beta-barrel like structure is observed its C-terminal region. Its specific function is unknown. Some of the members of this protein family are annotated as transcriptional regulators (see Q3EXU7, Q81I96).
Statistics
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PSSM-Id: 518533
Aligned: 22 rows
Threshold Bit Score: 115.81
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1SF9_A        27 KRYSQMTPHELNTEIALLSEKARKAEQHGIINELAVLERKITMAKAYLL-NPEDYSPGETYRV-ENTEDEFTISYLNGVF 104 Bacillus subtilis
Q8CV63         3 FRYSDYSIEQLHREIGDLKEKAQKAEQLGNVSEVQIYERKMQVALAYTI-NPDDFKKDEIYQLkMEPGYTFKIDYINGVF 81  Oceanobacillus ...
Q5WIG2         3 KRFSDMDEYELKLEIAMLNEKAKKAEQLGNSNEYAVYERRKILAQAYLM-DPAEIEPGQVYHMt-DGESFFEVSYLNGRF 80  Bacillus clausi...
WP_014371522   3 KLYSQMTREEIEHEMKRLREEMEQAE---FPSQKAVLESKYETAKSYTL-DPADFPPG-LYKV-HNVQLPFHVVYLNGIM 76  Paenibacillus m...
3_pfamImport   1 --YSQMTLAELQEEMERLHVEAKEKKKLGDHSQLAIITQKYFMAKSYYL-GTSEFRIGSKYSV-PDYDQPFTIDYFNGVF 76 
WP_012810386   1 mlYSEMSKEELRREMAELQRKGREAYERENWSEYEIYMTRWYLAKSYEIkDDVHIEIGRTYRIaEEYDR-LTVTAIEGVM 79  Alicyclobacillu...
Q81I96         5 KRYSEMTPHELREEIGALKEQAVKAEQLGIVNEFDVLMRKMAMARAYMT-DINKFHIGETYELvEEPGVLFKITYFNGVF 83  Bacillus cereus...
5_pfamImport   1 -TYSAMSEPELRQEIANLRERARKAEQLGIVNEYAVYERKALLAEAYLV-DLSTIIPGEIYRLnGSPGEFFQVDYLKGRF 78 
2_pfamImport   1 -----MTPHELQQITADYREKARKAEMMGIVNEYEVWMRKALIAESYLV-DAQKVQPGKVYALvGNPPEYFKVDRVKGVF 74 
Q5HN62         1 -----MSEQELRHEIQLFKEKMRKAEMNGIMNEYDVYQSKVIIAESYLV-DRNKIEPGKIYKLnDGSKQYFKVERLKGVF 74  Staphylococcus ...
1SF9_A       105 AWGYRTS----SPQQEEALPISVLQ 125 Bacillus subtilis
Q8CV63        82 AWGYRINlldeVREEIEALPISLLG 106 Oceanobacillus iheyensis
Q5WIG2        81 AWGYRT-----GERELVGVPISLLG 100 Bacillus clausii KSM-K16
WP_014371522  77 AWGTL------DGREEASFPISMLT 95  Paenibacillus mucilaginosus
3_pfamImport  77 AWGRFP-----DSDEQTGFPVGMLE 96 
WP_012810386  80 AWGIRQ-----MTGETTAVPIAQLE 99  Alicyclobacillus acidocaldarius
Q81I96        84 AWGYKQ-----NDNEEIGIPISLLQ 103 Bacillus cereus ATCC 14579
5_pfamImport  79 AWGHRLG----SERFEEALPVSILR 99 
2_pfamImport  75 AWGFRLG----GTLEEEGIPLALLQ 95 
Q5HN62        75 AWGFRIN----SSEPEEGLPLALLK 95  Staphylococcus epidermidis RP62A
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