1QZ7


Conserved Protein Domain Family
Axin_b-cat_bind

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pfam08833: Axin_b-cat_bind (This model is not part of the current CDD release)
Axin beta-catenin binding motif
This motif is found on the scaffolding protein Axin which is a component of the beta-catenin destruction complex. It competes with the tumour suppressor adenomatous polyposis coli protein (APC) for binding to beta-catenin.
Statistics
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PSSM-Id: 518532
Aligned: 34 rows
Threshold Bit Score: 34.6114
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1QZ7_B         33 ENP-ESILDEHVQRVMKTPGCQSPgtGR----------HS---P--KSRSPDG 69   African clawed frog
EEC18147      483 VNS-QSILDEHVSRVFDSPLTQTP-------------------P--RSTSPRR 513 
XP_013402826  492 DNS-QSILDEHCSRIWDSSTGQTP--SRsp------gkQT---Ps-RSKSPER 531 
XP_032795517  491 ADT-QSILDNHVQRIW---ADQTP--LR-----------SpgaPspRPWSPEN 526 
ROT81318      144 VDPcQSILDEHVSRVWQDSNNDTP--AR-----------SpgsP--RPKSPSG 181 
XP_014768259  510 ELA-DSILEEHCSRIWESSAQQTP--FRsp------ggHS---P--KPKSPER 548 
XP_021361581  527 DNP-NSILEDHVSRIWESSAQQTP--TRsp------gqQS---PslKRSAADR 567 
PIK60479      139 KDP-NSILDDHLHRVFDDSAKQSP--SG----------RS---SrsRSRSPDH 175 
XP_003729076  437 DDP-NSILEDHMSRVFKDSNRHTP--RG----------FS---P--RSRSPPD 471 
VDM31882      138 DNA-QAILEDHCSRIWDTSADRTP--TSssgsggdglgVSalrP--RLDAPGK 185 
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