Conserved Protein Domain Family
PilS

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pfam08805: PilS 
PilS N terminal
Type IV pili are bacterial virulence-associated adhesins that promote bacterial attachment to host cells. In Salmonella typhi, the structural pilin protein PilS interacts with the cystic fibrosis transmembrane conductance regulator. Mutagenesis studies suggest that residues on an alpha-beta loop and the C terminal disulfide-bonded region of PilS might be involved in binding specificity of the pilus.
Statistics
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PSSM-Id: 430227
Aligned: 5 rows
Threshold Bit Score: 129.206
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6D6L5  43 QRAEAEVKNIALIQAGTKSLYSAV-SSY----SGLAITTLVKAKVLPESIQK--TSGaa---sSMVNVWKGNISVSsadt 112 Pectobacterium atrose...
Q63JW9  56 ANTNRLAEELNAIQTGTKKLYMGQvNNYg---DADLNANLIAARVFPSTLPTg-NNN------TVSNAWGGNVTVT---- 121 Burkholderia pseudoma...
Q6D9S5  58 YQNSATQTEVTTMLEQSRK-LKSR-AGY----TGASMATLRAVNGIPTSVDR--TGD------IYYNRYGGTYSLApart 123 Pectobacterium atrose...
Q7N7Q2  50 KDAVVETTNLQTIISSTQGLMKGS-GGYefshADKMTGVLIQLGGVPKSMTV--RGDttvgnaTLWNTWGGQVKVGpss- 125 Photorhabdus laumondi...
Q7MB48  47 SEISTESSNITQMAANLKSIKNGA-KGY----DSLDNKIAINYKVVPTNMTQdgKSG------IIFNSWNGKVTISp--- 112 Photorhabdus laumondi...
Q6D6L5 113 gpsGAIGsSFIITYRSVPAVECAKLVSSLSAs---FYSIEIGAD------TVKDSngSLDIAGVT----SSCSRgg---e 176 Pectobacterium atrose...
Q63JW9 122 ---GAGR-TFTVQYTNVPRDVCINTLTAGGN----WQTVAIGGN------APINY--PVSPTNAT----ANCAD------ 175 Burkholderia pseudoma...
Q6D9S5 124 ngsAFNN-SVSLTLTGVSEGGCGDLSQMFLNagesIYSVTIGST------AMVTAnvTTGTSTAAtmigTQCDGg----- 191 Pectobacterium atrose...
Q7N7Q2 126 -tgGFNN-GFTVTYERVPQSACVSLATGMSRgg-sASEITINNT------HHADG--KVTLESAS----TACTRnngrtg 190 Photorhabdus laumondi...
Q7MB48 113 --gDTTAqTFKIEYQNVPDEACQQLSLKLRVa--gWSKMTVGGGggkgqqSATEIksDSTLAQIE----AACNAn----d 180 Photorhabdus laumondi...
Q6D6L5 177 NNTVSFTSL 185 Pectobacterium atrosepticum
Q63JW9 176 AATIVWTSN 184 Burkholderia pseudomallei
Q6D9S5 192 DKTVIITTS 200 Pectobacterium atrosepticum
Q7N7Q2 191 TNKLIFTIN 199 Photorhabdus laumondii subsp. laumondii
Q7MB48 181 ANTVTLVSA 189 Photorhabdus laumondii subsp. laumondii
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