2PI2


Conserved Protein Domain Family
RPA_C

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pfam08784: RPA_C 
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Replication protein A C terminal
This domain corresponds to the C terminal of the single stranded DNA binding protein RPA (replication protein A). RPA is involved in many DNA metabolic pathways including DNA replication, DNA repair, recombination, cell cycle and DNA damage checkpoints.
Statistics
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PSSM-Id: 400920
View PSSM: pfam08784
Aligned: 15 rows
Threshold Bit Score: 91.6695
Threshold Setting Gi: 121938487
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2PI2_B       166 HMVLSKANSQPSAG-----------RAPISNPGMSEA---------GNFGGNSFMPANglt-------vaQNQVLNLIKA 218 human
Q57ZN9       155 HLRLTQGSRRPSSAap--------aAVPNTASAVGVQ---------NMFPGGDGKVFT------------TDVVINTIRQ 205 Trypanosoma brucei
Q4CZG6       163 HLRLTRGDKHAKEEga-------vpAVSNTASTLGVQ---------NMLPGGGGKVFA------------TDVLLNAIKQ 214 Trypanosoma cruzi
Q6K9U2       162 HLENTKSQIGSPAKtysa----mgsSSSNGFSEMTTP---------TSVKSNPAPVLSvtngs---ktdlNTEVLNVFRE 225 Japanese rice
Q9ZQ19       163 HFYSQNSESQRQQVgdvt----qsvNTTFQGGSNTNQ---------ATLLNPVVSSQNndgng---rknlDDMILDYLKQ 226 thale cress
XP_011388982 170 HLQATRGPTASALKgats----talFNQAGGLESNDM---------NAYSGSKKQDVNdlykn---lgelPQQIMSIVTR 233 Ustilago maydis...
Q92373       167 HLHFTQKANAVNGAnapg----ygtSNALGYNNISSN---------GAANSLEQKLAEysl------tpaQMTVMQAIHS 227 Schizosaccharom...
Q7S8S2       162 HLFFTKGAPGSGGGakqeggggdnmFVDQGYGAGGGDvamggagpgGGNSAMQARLATcs--------rnAQIMCNFINN 233 Neurospora crassa
Q2UHC2       169 HLFFTRGPVGGSGG-----------AGAAAGGAGGAD---------ATMGGVDDYSAGrnlpa---mspvARRVYNLLKT 225 Aspergillus oryzae
Q5BFU8       171 HLFHTRGAPGPAAG--------------ATGKIDGGD---------AAMGGLDGAGVGggggfpanmsatARRVYNLLRT 227 Aspergillus nid...
2PI2_B       219 ---CPRPEGLNFQDLK-NQLk-HMSVSSIKQAVDFLSNEGHIYSTVDDD 262 human
Q57ZN9       206 k--ARGEEGLSMDEISaAALqyGFSGQDVRNAIRTLMEEGKIYQTHDCK 252 Trypanosoma brucei
Q4CZG6       215 n--ARGDAGLSMDELAaAARqyGFSVNDVRVALRTLAAEGSVYQTHDNR 261 Trypanosoma cruzi
Q6K9U2       226 panVESEHGVHIDEIV-KRF--RLPEAKIKVAIDYLADIGHIYSTIDES 271 Japanese rice
Q9ZQ19       227 pacTARQQGIHIDEIA-QQL--KIPKNKLEGVVQSLEGDGLIYSTIDEY 272 thale cress
XP_011388982 234 e-sQNHPDGVHVSLIA-RLLn-GVDVNDVKSAVEDLSSDGYLYTAADDN 279 Ustilago maydis 521
Q92373       228 a--PETNEGVHVRQLA-QSV---GPGIDLTAVTDFLQQEGIIYTTIDEN 270 Schizosaccharomyces pombe 972h-
Q7S8S2       234 s--PGGTEGVNLHVIA-QGT--RMSVRDITNAADELLGQGIIYTTQDDE 277 Neurospora crassa
Q2UHC2       226 e--PQSNEGLHAQLIA-AKL--SLPMPDVARAGDELLTAGVIFSTVDEQ 269 Aspergillus oryzae
Q5BFU8       228 e--PQNNEGLHAQFIA-AKL--GLPPQDVVRAGDELINAGMVFSTVDDQ 271 Aspergillus nidulans
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