Conserved Protein Domain Family
Rgp1

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pfam08737: Rgp1 
Rgp1
Rgp1 forms heterodimer with Ric1 (pfam07064) which associates with Golgi membranes and functions as a guanyl-nucleotide exchange factor.
Statistics
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PSSM-Id: 400883
View PSSM: pfam08737
Aligned: 73 rows
Threshold Bit Score: 266.831
Threshold Setting Gi: 562972865
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6FX98         135 NFVSCYLQVSGKLQYDNSIIDKSTFKSN-------Ds--KLLGVTyadsta---kqlneeSISksdkyvns--------- 193 [Candida] gla...
XP_011276477   152 DLLIGYIQLSGFFTYDEEVIDREKLKDFrnkaavaGkigGLEGLE---------------LSKtqneg------------ 204 Wickerhamomyc...
P16664         132 TLISGYVQISGVFQYDSEVISESKFKQD-------Ev--KMVGLDivpghtt-nsvlaleDGEhfkgkrnltny---lns 198 Saccharomyces...
CCF56860       133 NLISGYVQISGTFQYNASIIDDTKFSND-------Et--KIVGVNssmrteftnhaknke-------------tiayfqs 190 Kazachstania ...
CCK71889       142 DLISAYVQVAGMFQYNLDVIAEDQLQNK-------Ga--KIVGFDvlegagawnkvtqq-------------------he 193 Kazachstania ...
XP_002496701   133 ELMSGYVQIFGMFQFDPEVINETKLDKT-------Sv--KVVGLDtplshvtkkmsgtavEENdsnqpnslaky------ 197 Zygosaccharom...
CAR25147       113 SLTSCYVQIFGLFRYDPETLAPLQSDNS-------Gs--KLVGTGslk-------------------------------- 151 Lachancea the...
Q6CKD2         114 DLMSCFVQIVGQCSMDEAIINTDMLNTG-------SnvhQLVGIGskn----------asTDEnspmstvissffdtsmd 176 Kluyveromyces...
ybcl:Ecym_4238 113 EFFSFYVQILGSFKYNANVVDAKRFQHTs----------KLVGVEprtseektrsersnmd------------------- 163 Eremothecium ...
Q750W8         134 DLLSFYVQLVGQFWYSSEVLDMRKMQYT-------N---KLIAAQsqssppv-ggggsptISSrnelsepiahfv--dtd 200 Eremothecium ...
Q6FX98         194 eyanitegLrfGYREDEKIIn--dTNISMGANDRENSNaEYEQVPIFLIPQTLIFSEINLEPGEAKTFLFkSQPLNKEIC 271 [Candida] gla...
XP_011276477   205 ------ifgsvAHGIGNFFNtttdELEAEADSKKQELE---KLIPFFSTSQSLLFSELNLKPGDVKTFYF-KCKLPHTLP 274 Wickerhamomyc...
P16664         199 dytnvtngLlfSESGSRGRTgtynERTLMISNDTS-----IKTLPLLLIPQTLLFSEISLEPGEVRTFYFkSTKLPKDIC 273 Saccharomyces...
CCF56860       191 nfesvtsgLmkKNQIDGNGGlrnnTIAVLDSANFQDSE--YKSIPILLIPQSLLFSEITLQPGETKIFHYkSSKLPEDLV 268 Kazachstania ...
CCK71889       194 lsqysnssyefTANLDSRYVltpgANTGNDNSNAQYSEd-YKELPTFLIPQTLLFSEISLQPGEVKTFHFkSTKLPVDLC 272 Kazachstania ...
XP_002496701   198 fhskrsaqflgSSNVNE-DElkgdHNAVFTLAAHDESVe-YRQFPILLIPQTLLFSELNLEPGETKVFRFkSSKLSRMIP 275 Zygosaccharom...
CAR25147       152 -----isgRkkSNSEGLGGIlfanLDDVARESMTGKKQe-LQKKPILLVPQTLVFSEIMLEPGEVRSFQFrSPRLPPDLP 225 Lachancea the...
Q6CKD2         177 eisrkvapLmsTETIDTGD---------------------WIKAPFLLIPQTLLFSELILGPGETRLFKFkTDQLGKDLP 235 Kluyveromyces...
ybcl:Ecym_4238 164 -----------eiekfvntnmnglshaATQIDGGREGEqNQMDVPILVIPQTLLFTELTLNPGDLKVFHFkSAKLPLSLP 232 Eremothecium ...
Q750W8         201 lhsdpasqSvkGH------------------------------LPLVVVPQTLLFGELSLKPGEVRVFHFrSAALPQNLP 250 Eremothecium ...
Q6FX98         272 PTYMlSNFLSVLYDAEFGITGvvdgn-lipiAKKVPISIAPYVLEGGMQASSVLNRPAVIQGSGTV-KEIKsspssirra 349 [Candida] gla...
XP_011276477   275 PSYN-GSSIKINYHFIVGASLnkqi--pkplNIHFPLKIYPKFDEDGYQPTSNLDKFILLPSDKSLnEIVEssn------ 345 Wickerhamomyc...
P16664         274 PSYSsSKVASINYTLEVGADVlsddn-iekfSNRVPITIAPYISSNAEQYTSRLDKPAIILKTGNI-KELKprlftrkvs 351 Saccharomyces...
CCF56860       269 PTYRvSDNFSINYNMSFGVSKvisnt-ivpsTIGVPIYISPYVTKNGFQYNFQVDKPPVILSSATI-KELKkstgamkrs 346 Kazachstania ...
CCK71889       273 PSYThSRNVAVNYSLQFGVSTlshde-ivpyKTRIPITIAPFVDSNSGQYTAMVDKVPTIMQPGTI-KEVNvkqkrspss 350 Kazachstania ...
XP_002496701   276 PSYYvSPNISINYSLEVGMGRlyhgd-ieqdTIKVPINIAPFVSRSGAQYSPVLNEKVTIMEPGLV-KEVKqrqpsggrv 353 Zygosaccharom...
CAR25147       226 PSYKtSKNFKIQYYLNFGLTKigskg-ltpfNTDFQIHVCPFVDAQIRQFTSKLDAGITILAPGRV-KEVKdaqrsrrks 303 Lachancea the...
Q6CKD2         236 PSYTnSAHFNISYVVQVGLSVnapediphqhFYNFPISVQPFVDKSICQYEMPLDREVLITPPGKV-QDVGstikstkpr 314 Kluyveromyces...
ybcl:Ecym_4238 233 HSYSmSKNFNISYVLQIGGITettvp-mttvAFKFPLSICSYIDNRGCQYVSTLDQSTVILPPGHT-KEISeskrrrtts 310 Eremothecium ...
Q750W8         251 PSYTlGDTFKILYQLQVGGIIhcqas-idsvMFSFPLNVCSYLNEEGCQYIHELGHDPVILPVGQV-KERAhlqrrrstq 328 Eremothecium ...
Q6FX98         350 sapqnhvsntlerrysverrsslyerrlsinferknsNPTVVDD---IEPERLSLM---KENFIKIIS---DKETNYDd- 419 [Candida] gla...
XP_011276477   346 -----------------------------------grRSSFKSIkkiILTKPKLSQsnkKEKFLNKIEnliENDENFNqe 390 Wickerhamomyc...
P16664         352 ta-------------------------savsfgrrksSIIDIDSp-lEDNEFVKRV---KKNFIELVE---SNQNVSRd- 398 Saccharomyces...
CCF56860       347 vsv-----------------------ssaitfprrksSTTAN-----FQKESTEKIeflKKNFIKLIE---SNENEAKd- 394 Kazachstania ...
CCK71889       351 ----------------------------asmftrrssGNLLNDK---LSNDTIKLM---KQKFIELVE---DNKVGAMd- 392 Kazachstania ...
XP_002496701   354 vs------------------------stvhqharrpsAFSLMNS---DRNQDVEKL---IHNFAKLVE---SNQDEFGd- 399 Zygosaccharom...
CAR25147       304 s--------------------------ssillrrrssAQSVNFSesvSEGPKIS-----KDLFKKLIQsrfSSDEFNDd- 351 Lachancea the...
Q6CKD2         315 kltgq-------------------siqldreirrksvSSIGK-----PSGTSIEAM---KQKFKDVVSewnENDDSDVp- 366 Kluyveromyces...
ybcl:Ecym_4238 311 s--------------------------iaatfpkrksSVQSAE----DINGYLKRQsdiKKEFRDLIS---NEENAGGe- 356 Eremothecium ...
Q750W8         329 -----------------------------stftrhrsSIHSIMPsfqDRFNILENS---KKHFKELLNs--EREDCTDe- 373 Eremothecium ...
Q6FX98         420 -------iDKLVDNLVEVQFdkdekdkdskpdieleeeHKNEEYVVTr--------kRSDsVRDHIAELQntpnmqynv- 483 [Candida] gla...
XP_011276477   391 sdfnfdefQNLNNKQIISNFielvnnns---------------------nsiindskPISiIKEGYNF------------ 437 Wickerhamomyc...
P16664         399 -------iDELIDLQMGVQFgkdedssdpepndshfsnEMVTSAESSlrsdavtkrrKSYsVRDNISNLEqkmwndcsl- 470 Saccharomyces...
CCF56860       395 -------vDELIELQVAEQFpkldelsdneysvssvnlNK-----------------SNRsTRRNVKLLRetvtvsspe- 449 Kazachstania ...
CCK71889       393 -------iDQLVDKQLEVQFgnaedsetnedpfetgdaGIK----------------PSStTRDNIMGLKrsipknlskk 449 Kazachstania ...
XP_002496701   400 -------lEELVDSQMAIQFpeessdesptlmnsdekrEDENGYVTK----------RMStVSSNVSDLArltanrpar- 461 Zygosaccharom...
CAR25147       352 -------iEGLVDKIMECQFetnnyes-----segedtNSSQPQVRK----------DMGsVRENLNQLYngtaditnte 409 Lachancea the...
Q6CKD2         367 -------iDSLLGQQFETE--------------------------------------PSTsVRMNLSQFYftgipensi- 400 Kluyveromyces...
ybcl:Ecym_4238 357 -------fDELTEKLLKFQFgdnidsdhenvddmskllDNK----------------MHRaLRSNIQLLKsnlasmslp- 412 Eremothecium ...
Q750W8         374 ---------QLVEKLLTFQFgenytqeinddselsesfEEAQYREPRhlpi--sqhrNNSlVDDKVSQKP---------- 432 Eremothecium ...
Q6FX98         484 ----esyvidgvtMIPQL-ANlqsTYQINRNGETIAKVVFSKPFFMTSDDIDISVTLDDcd-erQTRITGISAILQSFVL 557 [Candida] gla...
XP_011276477   438 --------------EKQI-SKiqsQFIIARNGQSITTLTFSKPFYTIGEEIKLTLDLQNk----dLKTTGVLISLESIEL 498 Wickerhamomyc...
P16664         471 -----vksdensnLLPQL-INlqnAYQINRNNETMAKVSLSAPFYKTTDDINLVIELDPitt-plLKVTSLTVSLESFEI 543 Saccharomyces...
CCF56860       450 -----etpgtgtnMASQI-ANlqkRYIINRNGQFLAKISFSKLFYTTAEDISLVIHLDNda-ssQLKVSAINANLESMEL 522 Kazachstania ...
CCK71889       450 lmkqdqengnpktLISQLdSSlqrSYVINRNGTLIAKIGFSKLFYTTNDDIDLVIYPep---htGFKISAVNVSLESAEL 526 Kazachstania ...
XP_002496701   462 ----klgfneekgLIPQL-DNlqnIYQINWNGQSITRIVCSKRFYTITDDIDLVLELDHns-ppTHKVSAVTVTLESCEL 535 Zygosaccharom...
CAR25147       410 e-neneaqngstgPLPQI-KSlqkEFIINRNGEFVGKVRLANSFYTTSDDIDLAIDLANe---gRFKISAVTTSLKAFEL 484 Lachancea the...
Q6CKD2         401 -----detqsnssLLSQL-QSlqtEYVVKMNDKFICNLELSKPAYSVSDQIDIILDLKNvednsNFKVTAVTASIETFEL 474 Kluyveromyces...
ybcl:Ecym_4238 413 -----nieptgdsIQSVL-NNlkkDYVVNRNGEMVCKINLSKLLYFKSEDIDLIIEFpg---esKHKITAVTTTLEMVEV 483 Eremothecium ...
Q750W8         433 -------------LLHSVmDNlrkEYLVNRNGENICTISLSKLFYGVNDEIDLTILIPQk---sNYKVTGVSTALELLEL 496 Eremothecium ...
Q6FX98         558 LNPRFAVD-KTSKAARPKGKTVAVDNSISFDDFtSISFKLSPSKTPtnhiAGQFKSDIFQHKWMVLLKFVIQ 628 [Candida] glabrata
XP_011276477   499 IRDSFSA--DIDLTKTLPRIIPHHKESFSTFQTsHLPISINIPLSS----TPQFKTNIFEIKWCLSLKFILS 564 Wickerhamomyces ciferrii
P16664         544 INPKYKTE-GKGIGSKPKGNSVYEKHFICFDECkSVSVKLLPPRSPtnqiTGQFKTDVFQHKWMIGLKFVII 614 Saccharomyces cerevis...
CCF56860       523 INPKAAIDpSEDIVIKPKTHIISEFHVTCFDDStSIPLKLTTPKSPlnqlPSQFKTNIFQLRWIINLKLILI 594 Kazachstania africana...
CCK71889       527 LNKTYVLQ---SEQVRPFYHNVSDARSVCYDECqSIPLKLLIPRTPrnqiSSQFRTNIFELKWVLSFQFILI 595 Kazachstania naganish...
XP_002496701   536 INPEYVTD--LENLKKPQVNRIYDAHAICFDDCdRIPLKLIMPKTPmyqlASQFKTDVFQLRWMLGIKFVLv 605 Zygosaccharomyces rouxii
CAR25147       485 INPKYATE-ALSASIKQQGQVMDENRAICFEETpTLHIKLLPHRSPtnqiTSQFRTDVFQFKWMLCLKFVLl 555 Lachancea thermotoler...
Q6CKD2         475 INPKFSSD-ENISKKKPSGTLVYETHATNFDNCdKICMKLIPQCSPttyiTSQFKTNIFQLKWMLTFKFVMI 545 Kluyveromyces lactis
ybcl:Ecym_4238 484 INHRFLRD-KSRTKSKAITYPLYSTHSICFGECeKVPIKLLTYRSPsnipLCQFITNVFQVKFMISFKFVLv 554 Eremothecium cymbalar...
Q750W8         497 VNPDYLVN-QKSKKAQ--RYPVYEEHSICFEGCnDIPIKLLPSRSPtniyPNQFRTNIFQLSWTLCFKFVIV 565 Eremothecium gossypii
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