Conserved Protein Domain Family
DUF1786

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pfam08735: DUF1786 
Putative pyruvate format-lyase activating enzyme (DUF1786)
This family is annotated as pyruvate formate-lyase activating enzyme (EC:1.97.1.4) in UniProt. It is not clear where this annotation comes from.
Statistics
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PSSM-Id: 400881
View PSSM: pfam08735
Aligned: 45 rows
Threshold Bit Score: 273.664
Threshold Setting Gi: 290754083
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8TU89            60 MGGGPSAWAVRAHLKTGLPVYATEDAALTIHDNLERVKAFGVQI------------VSTedakklaASGE-ALEVIMQDF 126 Methanosarc...
WP_013886862      57 MGGGPITKALRNHIDKGYNVFISKDAAKTIKDDLEKVESWGFNI------------VEA-------VENP---HLELSDI 114 Flexistipes...
jgi:Maeo_0548     60 MGGGPVNRAISELQEQGYKIEISKNAAPTIRDDLDVVRRRGIII------------KDK-------IDNP---NIIFGDL 117 Methanococc...
jgi:Mvol_0249     57 MGGGAVSFQILKKIKQGYTVEISERCARTIRDDLDQVRQKGVII------------KDN-------IENP---NVILKDL 114 Methanococc...
Q6LXT0            57 MGGGPVSFAIMQKLKKGYKVEISERCARTIRDDLDEVREKGIVI------------KDE-------IKNP---NVNLEDL 114 Methanococc...
NZAGRC:Abm4_0032  57 MGGGKLKNAILEHMDKGYNVAMESYCAKTIRDDLKQVESYGIEVvyd-------kdKNN-------EKYKdYTRISLNDI 122 Methanobrev...
WP_012956956      57 MGGGKIKDRCLEHMEKGYKIVFEELSGKTIRDNIEQVKSFGFEVvkegsfdkelneDSS-------LKYAdYQKISLKDV 129 Methanobrev...
O27521            65 MGGGPVTRAILEHIGAGNRVVMTPEAARTVRDDPERVMAMGIEI--------------S-------EENPgLQSIEFRDV 123 Methanother...
WP_023991168      57 MGGGPVNKAIQNHLDKGYRVIMNEHSARTVRDDLERVRSMGVEIv-----------HLN-------EKHPeIAELEMTDV 118 Methanobact...
Q0W6L6            57 MGGGAITGALRAHTEK-HRVVMTPEAARTVRDDLEQVKERGIEIg-----------DES-------DMKGsYLKLTLMDV 117 uncultured ...
Q8TU89           127 DPCAVSCALSNFEVRMSE--NYAVAVQDHGNA-PDKSNRVYRFELLKELIEMGGKLENFVFLPEe-IPQAFTRMKAQADS 202 Methanosarc...
WP_013886862     115 DFELFEILQEKAFYGKFN--KILVAVQDHGYI-KGQSDRITRIDFLKEFL--DGDLSKAYFNKNtsIPQNFSRFRSIRET 189 Flexistipes...
jgi:Maeo_0548    118 NFEMLENIFKEFGEEFRPd-FVCVGCQDHGFV-KGQSDRITRFNYFKELLQITDNPFEYIFKQEteQLNQFSRFNSIIQY 195 Methanococc...
jgi:Mvol_0249    115 DFSTYKNIFSTLNMDFDPd-YVCVACQDHGFV-KGQSDRITRFKYFKEKLSETRNPYDFYFENS--KTGYFTRFNAILSS 190 Methanococc...
Q6LXT0           115 DFEMLKTIFSSMGQDFSPd-VVCVACQDHGFV-KGQSDRITRFKYFEKKLNETKDPYEFYFDNKkyKTDNFSRFESILKT 192 Methanococc...
NZAGRC:Abm4_0032 123 DIDKLAGFLKEYDLDFDFd-YIAVAVQDHGYN-ENMGDRDFRFEKIREKLENPLKPEEFGWYGN--IPEYYSRMKSVENK 198 Methanobrev...
WP_012956956     130 DVDKLIDIFKSFDLDLEVd-ELIIAVQDHGYS-EDMGDRDFRFEKIKEKLPEPLPPEVFAMEREe-VPEYFTRMQSVIQS 206 Methanobrev...
O27521           124 DLEAIRGALACFDVDLDFd-LLGVAVQDHGAG-GDMGDRNFRFMKIREKLSVPIPPEEFSYLGD--VPEYFTRMKSIEKA 199 Methanother...
WP_023991168     119 DLVAIKEALSNFDVELDFd-FIGVAVQDHGYN-ESMGDRNFRFQKIREKLNVPRAPEEFAYKGE--VPPYFTRMQAVQRT 194 Methanobact...
Q0W6L6           118 DMTAWEAGLAMLNYTLPKdiVVAVAVQDHGVApKGMSDREFRFEHIGKKVRKGATFKDFIFTKK---TNKFSRVSAVIQS 194 uncultured ...
Q8TU89           203 L--LKSttv-lktRAVFMDTGPAAVFGALIDPAAVQ--PAIVVNIGNGHTLGALVNE-NRITAIFEHHSSSMDPEKLQDY 276 Methanosarc...
WP_013886862     190 I--TNHyk---ntDFAITDTGIAAALGALYKNETR---PAVTIDAGNGHTFAALIHEeYKISSFFEHHTGMLDKKKIRYL 261 Flexistipes...
jgi:Maeo_0548    196 L--KNSg-----hSGFVMDSKVASICGILHYAKENDinEFVGLDIGNGHTLGVSIKD-GKIKALFEHHTRLLTPVKLNKI 267 Methanococc...
jgi:Mvol_0249    191 LesENEn-----yKGFVMDSKIASVCGIMNYANEQKinEYIGLDIGNGHTLGVSIKN-NLIYGLYEHHTRLLTTEKLLDY 264 Methanococc...
Q6LXT0           193 L--DENn-----yKGFVMDSKMASVCGILNYANENNinEFIGLDIGNGHTLGVSMQN-QKINGLFEHHTRLIDDQKLKDI 264 Methanococc...
NZAGRC:Abm4_0032 199 L--KNEtnwqirnTPLIMDTKFASICGMCYDEEALKlnSYIVMDIGNGHTTVASIEN-RKIQGVFEHHTSSLTGESLERY 275 Methanobrev...
WP_012956956     207 L--EESnp---efKPVLMDTKFASLAGVCYDKEVLKlnSFIVMDIGNGHTTVASIEN-GKIQGVFEHHTRDLSPERFEEL 280 Methanobrev...
O27521           200 I--R-H-------PTLIMDSKFASVTGALMDPAVSSdePIVVVDVGNGHTLAASILE-GRIHGVMEHHTRMLSPAKLEDF 268 Methanother...
WP_023991168     195 L--RNY-------NPLIMDSKFASICGATLDPMVKDmdRYIAMDVGNGHTLAVSFLD-GKIHGIFEHHTGILTPKRIEEL 264 Methanobact...
Q0W6L6           195 L--KDQgy----eNVLVMDTKIAGIYGGLYGEKL----PAIVMDVGNGHTTAASIAEdGTIVGIFEHHTASLTPAKMRLY 264 uncultured ...
Q8TU89           277 IIRLADGALGFEEVFDDGGHG---AYIKEVCGFEQVSSIMVTGPKREM 321 Methanosarcina acetivorans
WP_013886862     262 VNKMLRGELTNEEIFNDGGHGa---hRFSGKSFPEDVPLIITGPNRHR 306 Flexistipes sinusarabici
jgi:Maeo_0548    268 VNKMINGTLTNEEIFNDRGHGatvVGGINP------EKILISGPNRAL 309 Methanococcus aeolicus Nankai-3
jgi:Mvol_0249    265 NEKLKNCTLTTEEIYNDEGHGacsLESLNT----NLTKTYIAGPNRRI 308 Methanococcus voltae A3
Q6LXT0           265 VERTCNGSLKNEDIYNDNGHGacvTCKTKP------ESILIAGPNREL 306 Methanococcus maripaludis
NZAGRC:Abm4_0032 276 VKKLANGTLTNEEIYNDHGHGahvINPISN-----IEKVIVSGPKRSL 318 Methanobrevibacter sp. AbM4
WP_012956956     281 VLALADGTIKHEDVHDEGGHGafaLNPISK-----IEKVVVAGPKRAL 323 Methanobrevibacter ruminantium
O27521           269 IIRLCLGELTHGEIHGDGGHGahvIDAVGE-----PVKVVATGPRGAy 311 Methanothermobacter thermautotrophicus str....
WP_023991168     265 INKLAAGTITHEEVHEEQGHGawvIDAIDS-----YECIVATGPKRAI 307 Methanobacterium sp. MB1
Q0W6L6           265 LEKLAEGTLTNEEIFEDEGHGayvKEPVKP------VSIIATGPRRDL 306 uncultured methanogenic archaeon
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