4LMG


Conserved Protein Domain Family
AFT

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pfam08731: AFT 
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Transcription factor AFT
AFT (activator of iron transcription) is an iron regulated transcriptional activator that regulates the expression of genes involved in iron homeostasis. This family includes the paralogous pair of transcription factors AFT1 and AFT2.
Statistics
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PSSM-Id: 400877
View PSSM: pfam08731
Aligned: 8 rows
Threshold Bit Score: 135.667
Threshold Setting Gi: 1160421719
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4LMG_C  15 FEDRHEIKPWLQK-IFYPQGIDIVIERSDSSKVTFKCRSVRSKVGLNP-------------------------------- 61  Saccharomyces cerevis...
Q6FSP0  42 FQEKIDVKVWLQE-MFFPMGIDIVIERSDKTKIIFKCKPSDYRSHEPKdl------------------------------ 90  [Candida] glabrata
Q755B2  89 FKDKNDIKPWLQK-IFYPQGIEIVIERSDKIKVVFKCKASKRTKSGSApgsqagaaedelggqy---------------- 151 Eremothecium gossypii
P22149 108 FEDKSDIKPWLQK-IFYPQGIELVIERSDAFKVVFKCKAAKRGRNARRkrkdkpkgqdhedekskinddeley------- 179 Saccharomyces cerevis...
Q6CS78  99 FKDKSEVKPWLQK-IFYPQGIEIVIERSDSMKIVFKCKAVKKNRNTSSisgcghshgvgsdscntngknstkgngsndnk 177 Kluyveromyces lactis
Q59Z29  21 FDSKDDIKPWLQDnLQSTKGINVVIERSDTSKIIFKCKNKEKKTKIVEsk------------------------------ 70  Candida albicans SC5314
Q6BK98  21 FTNKDDIKPWLQNyLLHKKGIHVVIARSDANKIVFRCKSDKSKET-AE-------------------------------- 67  Debaryomyces hansenii
Q6FS49  15 FKDKNEIKPWLQK-IFYPQGIEIVIERSDSLKVVFKCKAAKRGRKSQEelteeerlrqea-------------------- 73  [Candida] glabrata
4LMG_C  62 ----------------------------------------KSKGSSSRSHACPFRIRAAYSVRLQKWNVVVMNNIHSHEL 101 Saccharomyces cerevis...
Q6FSP0  91 ---------------------------------------rQKEPVDDKRHICPFRVRCTFSTQLKKWKIVIINNSHSHPL 131 [Candida] glabrata
Q755B2 152 -------------------------etlplspvvtasqlrKKKRAVSPYNTCPFRVRAAYSLKRKRWSIVVVNNGHSHPL 206 Eremothecium gossypii
P22149 180 ----------------aspsnatvtngpqtspdqtssikpKKKRCVSRFNNCPFRVRATYSLKRKRWSIVVMDNNHSHQL 243 Saccharomyces cerevis...
Q6CS78 178 crkkgigkgfaecdgletetengnnsnstvgggngsndtdKKKRAIGPYNSCPFRVRATFSLKRKKWNIVVVNNVHTHPL 257 Kluyveromyces lactis
Q59Z29  71 --------------------------------------ktASKTMIRKHTSCPFKIRANYSVRNKVWTLSIVSDEHDHVV 112 Candida albicans SC5314
Q6BK98  68 ----------------------------------------KLSLGSRRQISCPFKIRANYSIRNHVWTLVVMNENHDHEL 107 Debaryomyces hansenii
Q6FS49  74 ----------------------------larehemkrksmGNKRCVSRYNHCPFRVRATYSLKRKKWSVVVLNNTHTHPL 125 [Candida] glabrata
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