5BZ0


Conserved Protein Domain Family
Viral_protease

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pfam08715: Viral_protease 
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Papain like viral protease
This family of viral proteases are similar to the papain protease and are required for proteolytic processing of the replicase polyprotein. The structure of this protein has shown it adopts a fold similar that of de-ubiquitinating enzymes.
Statistics
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PSSM-Id: 400865
View PSSM: pfam08715
Aligned: 3 rows
Threshold Bit Score: 452.911
Threshold Setting Gi: 190360108
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5BZ0_A    4 TCKQKTIYLTEDGVKYRSIVLKPGDSLG-QFGQVYAKNKI---VFTADDVEDKEILYVPTTD-------KsilEYYGLDA 72   Avian infectious br...
P0C6X1 1599 EAKVITIKVTEDGVNVHDVTVTTDKSFEqQVGVIADKDKDlsgAVPSDLNTSELLTKAIDVDwvefygfKdavTFATVDH 1678 Human coronavirus 229E
P0C6X7 1541 EVKTIKVFTTVDNTNLHTQLVDMSMTYGqQFGPTYLDGADvtkIKPHVNHEGKTFFVLPSDDtlrseafE---YYHTLDE 1617 Severe acute respir...
5BZ0_A   73 QKYViYLQTLaqkw--nvqyRDNFLILEWRDGNSWISSAIVLLQAAKIRFKG-FLTEAWAKLLGGDPTDFVAWCYASCTA 149  Avian infectious br...
P0C6X1 1679 SAFA-YESAV----------VNGIRVLKTSDNNCWVNAVCIALQYSKPHFISqGLDAAWNKFVLGDVEIFVAFVYYVARL 1747 Human coronavirus 229E
P0C6X7 1618 SFLGrYMSALnhtkkwkfpqVGGLTSIKWADNNCYLSSVLLALQQLEVKFNApALQEAYYRARAGDAANFCALILAYSNK 1697 Severe acute respir...
5BZ0_A  150 KVGDFSDANWLLANLAEHFDADYTNAFLKkRVSCNCGIK-SYELRGLEACIQpVRATNLLHFKTQYsncPTCGANNTDEV 228  Avian infectious br...
P0C6X1 1748 MKGDKGDAEDTLTKLSKYLANEAQVQLEHySSCVECDAKfKNSVASINSAIV-CASVKRDGVQVGY---CVHGIKYYSRV 1823 Human coronavirus 229E
P0C6X7 1698 TVGELGDVRETMTHLLQHANLESAKRVLN-VVCKHCGQK-TTTLTGVEAVMY-MGTLSYDNLKTGVsipCVCGRDATQYL 1774 Severe acute respir...
5BZ0_A  229 IEASLPYLLLFAtd-gPATVDCDEDAVGTVV--FVGSTNSGHcYT--QAAGQAFD--NLAKDRKFGKKSPYITAXYTRFA 301  Avian infectious br...
P0C6X1 1824 RSVRGRAIIVSVeqlePCAQSRLLSGVAYTA--FSGPVDKGH-YTvyDTAKKSMY--DGDRFVKHDLSLLSVTSVVMVGG 1898 Human coronavirus 229E
P0C6X7 1775 VQQESSFVMMSA----PPAEYKLQQGTFLCAneYTGNYQCGH-YTh-ITAKETLYriDGAHLTKMSEYKGPVTDVFYKET 1848 Severe acute respir...
5BZ0_A  302 FknetSLPVAK 312  Avian infectious bronchitis virus (strain Beaudette)
P0C6X1 1899 Y----VAPVNT 1905 Human coronavirus 229E
P0C6X7 1849 SytttIKPVSY 1859 Severe acute respiratory syndrome-related coronavirus
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