1M1J


Conserved Protein Domain Family
Fib_alpha

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pfam08702: Fib_alpha 
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Fibrinogen alpha/beta chain family
Fibrinogen is a protein involved in platelet aggregation and is essential for the coagulation of blood. This domain forms part of the central coiled coiled region of the protein which is formed from two sets of three non-identical chains (alpha, beta and gamma).
Statistics
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PSSM-Id: 400857
View PSSM: pfam08702
Aligned: 71 rows
Threshold Bit Score: 153.085
Threshold Setting Gi: 768942638
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1M1J_E         67 AGGCKHPLDELGVLCPTGCELQTTLLKQEKTVKPVLRDLKDRVAKFSDTSTTMYQYVNMIDNKLVKTQKQRKdNDIILSE 146 chicken
XP_006010728   50 KEWPLCTTDQWGPKCPSGCRMQGLINNADKEIAERIDKIRKFLAENQNNYKSASLVTRQTHDSLRNTLLGNEdSDRQYSQ 129 coelacanth
XP_006629594   48 KEWPICLDEDWGPKCPSGCRIQGLLTKADKDLADKIDKIRKFLDENRNKYRSADQITKTTYDVLREKLVLNTgADNRFQN 127 spotted gar
NP_001181918   46 KEWPGCTDDDWGSKCPSGCRVQGLMDKADHDLLKKIEKIRRLLVEGQKLYRSADEVSKTTYTYLREKLTSNSgYDNRYMS 125 zebrafish
XP_013119750   41 KEWPFCTDVEWGPKCPSGCRIQGLMEKYDHNMLKKIEKIRSLLDQNKAKHRSADTVSKQTYDYLKEKLTTDAgSDNNYFD 120 Nile tilapia
10_pfamImport   2 KEWPFCTDDQWGPKCPSGCRIQGLMDRFEHGSLKRVEKIRSLLDQHRAKHRSTDLVTKQTYDYLKEKLTSDAgNDNSYYD 81 
XP_003221786   50 KSWPTCSDEEWGIKCPSGCRMQGLIDETDREFNDRINKIKKLLSDNQNSYKKSNILKQELTSFLERNLVDEQeLDNGYGQ 129 green anole
NP_001258840   50 KNWPICVDDDWGTKCPSGCRMQGIIDDTDQNYSQRIDNIRQQLADSQNKYKTSNRVIVETINILKPGLEGAQqLDENYGH 129 chicken
OWK55638       50 KSWPICADDDWGTKCPSGCRMQGLIDEKDQEFSHRIDKIKKLLSDNQNNYKKSNQIIVETVNALKPNLDSAQeLDETYGR 129 Bengalese finch
CAF87511       43 KEWPFCSDDDWGPKCPSGCRIQGLMDKHDFSLLKKIEKIRNLLDQNKAKFRTADQASKQTYDYLKDKLTLDSdNSNKYYA 122 spotted green ...
1M1J_E        147 YNTEMElHYNYIKDNLDNNIpSSLRVLRAVIDSLHKKIQKLENAIATQTDYCRSPCVASCNIP 209 chicken
XP_006010728  130 VVVNLQrRLSILHQRVTAQL-DRIRKLRSLVQDQIYEMQRIEVDIDIKIRACKGSCFKShlyn 191 coelacanth
XP_006629594  128 LADQLRqRIIEMKLKIDQQN-SLLIALKSRVRDQVNEVHRIEVDIDIKIRSCKGSCASAheyt 189 spotted gar
NP_001181918  126 LAEQLRqRITDIKIKIDRQL-RLLDALKSQVKDQVVVMQRLEVDIDIKLRTCKGSCASYSEfs 187 zebrafish
XP_013119750  121 LAQTLRqRITDMKIKIDRQV-TVLAALRDRVKDQVIEMQRLEVDIDIKLRSCKGSCAGYSEYQ 182 Nile tilapia
10_pfamImport  82 LAQGLRqRISDMKIKIDRQL-SILRALKQRVGDQVVEMQRLEVDIDIKLRSCKGSCQSY---- 139
XP_003221786  130 ISDDLRrRLVTLKQRVFNQV-NRIKVLQNTIRNQVGELKRLEVDIDIKIRACKGSCARTYNyh 191 green anole
NP_001258840  130 VSTELRrRIVTLKQRVATQV-NRIKALQNSIQEQVVEMKRLEVDIDIKIRACKGSCARSFDYQ 191 chicken
OWK55638      130 LSGELRrRIMTLKQRVVTQV-NRIKALQSSIQEQVVEMKRLEVDIDIKIRACKGTCARSFDYK 191 Bengalese finch
CAF87511      123 LAQNLRrNINDMKIKIDAQL-RALAALKDRVRDQVSEMQRLEVDIDIKLRSCKGSCERYSayq 184 spotted green pufferfish
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