Conserved Protein Domain Family
ArgoL1

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pfam08699: ArgoL1 
Argonaute linker 1 domain
ArgoL1 is a region found in argonaute proteins. It normally co-occurs with pfam02179 and pfam02171. It is a linker region between the N-terminal and the PAZ domains. It contains an alpha-helix packed against a three-stranded antiparallel beta-sheet with two long beta-strands (beta8 and beta9) of the sheet spanning one face of the adjacent N and PAZ domains. L1 together with linker 2, L2, PAZ and ArgoN forms a compact global fold.
Statistics
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PSSM-Id: 400854
View PSSM: pfam08699
Aligned: 235 rows
Threshold Bit Score: 30.5535
Threshold Setting Gi: 189190814
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002639226  279 TVLQSFFSITphtkigpshglGWgtvnLgL-GREVCYGFYQNVVETFDKLTMNIDVATTTFYR 340  Caenorhabditis briggsae
EFJ26136      295 PSGRNFFDPSfg--------rLA----L-EgGFEAWKGFYQSVRPTMQGLVLNVDLSAAAFYE 344  Selaginella moellendorffii
EEF38697      293 PVGRSFFS-Pdlg------qkGE----L-GdGIEYWRGYYQSLRPTQMGLSLNIDVSARSFYE 343  castor bean
XP_002880962  304 SVGRSFFH-Tslgkd-trdgrGE----L-GdGIEYWRGFFQSLRLTQMGLSLNIDVSARSFYE 359  Arabidopsis lyrata subsp. lyrata
XP_006347212  320 vVGRSLFHNEsed------dtGS----L-TgGLEFWRGYYQSLRPTQMGLALNIDMSARAFYE 371  potato
XP_006838856  260 PVGRSFFS-Skf-------gkEE----I-GdGLECWRGFYQSIRPTQMGLSLNTDVSTTAFYE 309  Amborella trichopoda
ERN11272      343 PVGRNFYS-Pklg------kiEK----M-PdGLECWRGYYQSILPKQMGLSLNIDMSSTSFYD 393  Amborella trichopoda
XP_002118712  163 MVYRSFYPEPa----------DDdwrsLgC-GHESWRGYYQSARSTQTGLSLNIDTSHTAFYE 214  Trichoplax adhaerens
XP_015785548  198 pLGNCIFPKSe----------NAdsinIgC-GKQVISGHYQSIRPTASGLSLIIDKSSTTFYN 249  two-spotted spider mite
XP_002952894  402 vLGRGYYYPG------------DgvepLtG-GAEVWKGFQQSFKLVESGLMLNLDSSFAAFMs 451  Volvox carteri f. nagariensis
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