7SWF,7YFY


Conserved Protein Domain Family
ArgoL1
?
pfam08699: ArgoL1 (This model is not part of the current CDD release)
Argonaute linker 1 domain
ArgoL1 is a region found in argonaute proteins. It normally co-occurs with pfam02179 and pfam02171. It is a linker region between the N-terminal and the PAZ domains. It contains an alpha-helix packed against a three-stranded antiparallel beta-sheet with two long beta-strands (beta8 and beta9) of the sheet spanning one face of the adjacent N and PAZ domains. L1 together with linker 2, L2, PAZ and ArgoN forms a compact global fold.
Links
?
Statistics
?
PSSM-Id: 518443
Aligned: 217 rows
Threshold Bit Score: 35.194
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
7SWF_A         285 PVGRSFFSPDikTPQRL-GeGLESWCGFYQSIRPTQMG-------L-SLNIDMASAAFIE 335  thale cress
O74957         159 gfMHSFFTGE--NGVSL-GgGVEAWKGFYQSIRPNQGF-------M-SVNVDISSSAFWR 207  Schizosaccharomyces pombe 972h-
CBJ30598       272 CVGRSFFT-Pdmp-spI-SgGAEVWLGYYQSLRATQAG-------L-TLNVDMSAMAFVR 320 
XP_002499467   208 SIGRNFLDSK--NTVKLsG-GFEVWKGYSLSARPTQGAegagathL-VV--NMAAGAFis 261 
XP_025174874   173 SLGRGIYASNn-NRVILsG-GAELRQGHCQSLRVGWND-------L-TVNVDVCSGIFCp 222 
XP_005847187    72 PVGRAFFFHDdqv-rsI-GgGAEVWLGYQQSLRPCQTG-------L-ALNIDMAATAMLE 121 
14_pfamImport    1 -TGNKFYTMD--GSRPLpQ-GAMVCKGFLQSFRYSNSA-------VpLINIDLGFSAFLQ 49  
Q5KAT1         192 AAGRKFFTEE--DGVAIsG-GAVVYRGFKQSFRWTSSG-------YpAVQLDNATSAFIE 241  Cryptococcus neoformans
XP_002952894   402 vLGRGYYYPGd-GVEPLtG-GAEVWKGFQQSFKLVESG-------L-MLNLDSSFAAFMs 451 
XP_002906081   252 VVGRNLFNGNga--ksL-GeGAELWFGYFQSLRATQNR-------L-VVNLDLAATAFVE 300  Phytophthora infestans T30-4
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap