3NCV


Conserved Protein Domain Family
MutL_C
?
pfam08676: MutL_C (489796 is an unknown moldel)
MutL C terminal dimerization domain
MutL and MutS are key components of the DNA repair machinery that corrects replication errors. MutS recognizes mispaired or unpaired bases in a DNA duplex and in the presence of ATP, recruits MutL to form a DNA signaling complex for repair. The N terminal region of MutL contains the ATPase domain and the C terminal is involved in dimerization.
Links
?
Statistics
?
PSSM-Id: 489796
Aligned: 78 rows
Threshold Bit Score: 87.66
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
3NCV_A  33 IAQLLGIYILAQAEDSLLLIDMHAAAERVNYEKM-KRQ--RQEngnlQSQHLLIPVTFAASHEECAALADHAETLAGFgL 109 Neisseria gonorrhoeae...
Q7MYT9 455 LSIYSPCYALIESPLGLGLLSLPVAERWLRQAQL-APT--EQGl---KSQPLLIPLKLSLSKEEAGALNRYSDLLGSFgI 528 Photorhabdus laumondi...
Q8ZIW4 459 LTVFPPCYALIEYQGGVALLSLAVAERWLKQAQL-SPP--EEGl---RPQPLLIPLKITLDKNEIAACQNHEKLLITMgI 532 Yersinia pestis
Q87L05 487 LVVVDEQFVLMSSDSGVALVSLPRSEFYRTKGQLtPSE--GAL----KAQPLLVPLSMKLDTDLVRLAQDYQQDFAQLgI 560 Vibrio parahaemolytic...
Q9KV13 474 IQVVAGQYLLMSSPQGCVLISLYQAQQLKLRGLLnAQH--GAL----KAQPLLVPLALKLNESEWQVAQRHSSALLQLgI 547 Vibrio cholerae O1 bi...
Q6LM28 535 LSIVAERYLLVSRHDGIHVLSLDHAQRLHHKGQL-RLA--ATEg--lKPQPLLIPHSVPVEPDLITCAEQHALLLKQLgI 609 Photobacterium profundum
Q5E2C6 483 LSVVESTFALLQQGKQLQLLNLRYAEFVKIYGQL-SSVnvEPL----KPQPLLIPLSVGIDESICNNLSNYASLLKSLgI 557 Aliivibrio fischeri E...
P57886 449 LALVENKALLLQQQQQFYLLSLQQLQRLKIELSL-Q----RDPv---LQQPLLIPIVFRLNPQQLTYWQQQKTFFTQIgF 520 Pasteurella multocida...
P44494 462 LSLIENRALLLQQNQDFFLLSLEKLQRLQWQLAL-K----QIQi---EQQALLIPIVFRLTESQFQAWQQYSDDFKKIgF 533 Haemophilus influenza...
A6VN10 471 VALVNNQALLLQRDTAFYLLPLNKLQKMRLELLL-T----LPNt---PQQMLLIPVVFRLSDKQQAQWRQQKIWFEQSgF 542 Actinobacillus succin...

3NCV_A 110 ELSD-MGGNTLAVRAAPVMLGKSdvVSLARDVLGELAQVGSsqt-iaSHENRILATMSCHGSIRAG---RRL 176 Neisseria gonorrhoeae FA 1090
Q7MYT9 529 EAS--VSHGKATLCAVSLPLRQQnlPKLIPELLGYLAQQPs------ASAEQVVTWLARHIGSEY----ETW 588 Photorhabdus laumondii subsp....
Q8ZIW4 533 ELS--VEQGRATLRAVSLPLRQQnlQKLIPELLGYLSQHEe------ISPDTLATWLARHLGSEHEvwnVSQ 596 Yersinia pestis
Q87L05 561 QLKA-RNDKALMVMGVPAPLRQQnlQNLVPDLLSYAQTWMKgekastQMLPALIDWLAVQVTTVK----SHY 627 Vibrio parahaemolyticus RIMD ...
Q9KV13 548 ELKS-RTNHSIMVMAVPQPLRQQnlQQLLPDLLSYAASCSEsq---aLSHQALADWLTQRIVVEK----RDY 611 Vibrio cholerae O1 biovar El ...
Q6LM28 610 NLKA-KGKSGLIILSVCLPLRQQnlQQLIPNLLTYLLSIAEdp--daQGWDKLWDWLATQCVMPV----DTF 674 Photobacterium profundum
Q5E2C6 558 DLKV-KNRTNIIVMAVCQPIRQQnlQQLIPNLLRYLEQIN-------PSLEQVIKWLSHQIQHDE----VSY 617 Aliivibrio fischeri ES114
P57886 521 EFHEnLGQQRITLNRVPSCLRQQnlQKCIIVLLSQ-------------PLDTFSHFLTTLCDVIELe--QIT 577 Pasteurella multocida subsp. ...
P44494 534 EFIEnQAQLRLTLNKVPSALRTQnlQKCVMAMLTR-------------D-ENSSSFLTALCAQLEC---KTF 588 Haemophilus influenzae Rd KW20
A6VN10 543 EFIEnPVQHRITLNAVPQCLRHQnlQKIVIALLNR-------------SLQKTEKFLTALLDLVELp--DCQ 599 Actinobacillus succinogenes 130Z
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap