8Q84


Conserved Protein Domain Family
DASH_Dam1
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pfam08653: DASH_Dam1 (This model is not part of the current CDD release)
DASH complex subunit Dam1
The DASH complex is a ~10 subunit microtubule-binding complex that is transferred to the kinetochore prior to mitosis. In Saccharomyces cerevisiae DASH forms both rings and spiral structures on microtubules in vitro. Components of the DASH complex, including Dam1, Duo1, Spc34, Dad1 and Ask1, are essential and connect the centromere to the plus end of spindle microtubules.
Links
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Statistics
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PSSM-Id: 518409
Aligned: 43 rows
Threshold Bit Score: 72.9681
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
8Q84_I        63 LLPKIRELSDSIITLDSNFTRLNFIHESLADLNESLGSLLYGIMSNSWCVEFSQAP 118 brewer's yeast
KDE04627      55 LAPVFAELADSLSDLTGNLRELDKSNDHLDGFNTAFASYLYGLRITAYTADFNEAP 110
XP_007406336  56 ISPLFSDLSDSIQDLHTNLIRLDQVCENLNGFNQSFSSYLYGLRMIYYTTDFDEAP 111
1_pfamImport   1 LAPALQDLADEVAALSTNTQRISALHDALGQFNEGFAAYLYALKMNAFCVEWPQAP 56 
XP_006960145  41 LTPALSDLSDELDGILSSTHQMVELDKALADFNHGFGSLLWALKLNAYCVNWPEAP 96 
ELU43210      36 LEPAFAEFADEAAAMHRNIERMGDLYETLETFNESFSSFLYALNMNAYTVEWPQAP 91 
EMD37276      39 LEPAMSELVDEAESLNTNVSGLKNLGDALTTFNESFASLLYVMNMNALTTDWPQAP 94 
ESK96200      45 LGPAMSEFTDEIDTLQANVEGMKRLSDSLGTFNESFASWLYIMDMNALTTDWPQAP 100
XP_007332065  39 LEPALAEFVDETEALQSNVEGLVNLSDSLATFNESFASWLYVMNMNALTTDWPQTP 94 
XP_067511324  32 LGPALEQLNKSIRNVSDKYEKLNDLDGALIDFNRSFGSFLFGLQANNETIHWkhsp 87
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