6I52


Conserved Protein Domain Family
Rep_fac-A_C

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pfam08646: Rep_fac-A_C 
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Replication factor-A C terminal domain
This domain is found at the C terminal of replication factor A. Replication factor A (RPA) binds single-stranded DNA and is involved in replication, repair, and recombination of DNA.
Statistics
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PSSM-Id: 400808
View PSSM: pfam08646
Aligned: 29 rows
Threshold Bit Score: 148.525
Threshold Setting Gi: 75025189
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6I52_C         25 FFSVKAAISFL-----KVD-NFAYPACSn-----eNCNKKVLEQ-PD-GT-----------WRCEKCDTNnARPNWRYIL 80   Saccharomyces...
Q9U0J0        966 MFTTYGFIDQI-----YNN-MPVYSACP-------DCNKKMISNsVDdNEyepssnlleetMYCAKCNKN-NIPVYNYYI 1031 Plasmodium fa...
XP_003968567  445 YYTCIATIVYL-----RKE-NCLYQACPs-----qDCNKKVVDQ-QN-GM-----------FRCEKCDKEfPNFKYRLIL 500  torafugu
XP_028043039  441 YYSLLGVLTFT-----FSE-NAVYKACPq-----eQCNKKLVDQ-EN-GL-----------FRCEKCNREyPNYKHRILL 496  wild silkworm
Q7PXI6        454 YFQVKAMIHTI-----KSA-NAVYKACPq-----aDCNKKVIDQ-EN-GQ-----------FRCEKCNAEfPNFKYRLLV 509  Anopheles gam...
Q24492        444 YFQCKAVVHIV-----KQE-NAFYRACPq-----sDCNKKVVDE-GN-DQ-----------FRCEKCNALfPNFKYRLLI 499  fruit fly
Q65XV7        592 WITVKAAISHV-----TTE-SFCYPACPkllpvgrQCNKKAINN-GD-GM-----------WHCDRCDESfQNPEYRYML 652  Japanese rice
F4JSG3        512 WITVSATILYL-----KFD-NFCYTACPimn-gdrPCSKKVTDN-GD-GT-----------WRCEKCDKSvDECDYRYIL 571  thale cress
Q9SKI4        483 WITVKATISFI-----KTD-SFCYTACPlmi-gdkQCNKKVTRS-GT-NR-----------WLCDRCNQEsDECDYRYLL 542  thale cress
Q4N547        284 YFIFICKLRKLfwknkDGEmRLWYHACP-------TCLKKVVEE-QE-NV-----------WRCITCDDSiVTPVLRYIV 343  Theileria parva
6I52_C         81 TISIIDETNQLWLTLFDDQAKQLL-GVDANTLMSLKE----EDPNEFTKITQSIQMNEYDFRIRAREDTYNDQSRIRYTV 155  Saccharomyces...
Q9U0J0       1032 NLKITDSTDSIRASAFANCAKIIMnGLSAEEYMKLRQeyimQENIENFDIIEKIKLNEFFFRIKVYMTSHMDELKKNYTI 1111 Plasmodium fa...
XP_003968567  501 SANIADYGDNQWVTCFQESAEAIL-GQNAAYLGQLKE----SNEAAFDEVFQQANFNSFIFRSRVKLETYNDESRIKATV 575  torafugu
XP_028043039  497 AANVSDPTGDQRVTLFNEAAETML-GKSAEEIARLSE----YDKNEYNKIFDEVKFKTFVFKFRTKMENFNDESRLKTTV 571  wild silkworm
Q7PXI6        510 NMLIGDWTSNRWVTVFTELAEEML-GKSSQEIGSSLE----YQKEEAEKLFTSISFKSFVFKLRTKVEYFGEQPRNKTSA 584  Anopheles gam...
Q24492        500 NMSIGDWTSNRWVSSFNEVGEQLL-GHTSQEVGEALE----NDPAKAEQIFSALNFTSHIFKLRCKNEVYGDMTRNKLTV 574  fruit fly
Q65XV7        653 RFQIQDHTGSTYASAFDEAGEQIF-GRKAGELFSIRNv--dQDDAQFAEIIEGVRWHLYLFKLKVKEETYNDEQSLKCTA 729  Japanese rice
F4JSG3        572 QLQIQDHTDLTCVTAFQEAGEEIM-GISAKDLYYVKNe--hKDEEKFEDIIRKVAFTKYNFKLKVKEETFSDEQRVKATV 648  thale cress
Q9SKI4        543 QVQIQDHTGLTWITAFQETGEEIM-GCPAKKLYAMKYe--lEKEEEFAEIVRDRLFHQYMLKLKIKEESYGDEQRVKMTV 619  thale cress
Q4N547        344 SCVFVDFSGQLFSTVYSESGKKLL-GYSEQELDAMDKee-lKNTLDFDVLHKDFKVSGFF-----KNKTYNGESRNTFNV 416  Theileria parva
6I52_C        156 ANLHSLnyraeADYL 170  Saccharomyces cerevisiae S288C
Q9U0J0       1112 IDIAPV-----GKLL 1121 Plasmodium falciparum 3D7
XP_003968567  576 MEVKPVdhkdySKRL 590  torafugu
XP_028043039  572 VNVQPVdykdgIARl 586  wild silkworm
Q7PXI6        585 VSVAPVnhkeyNALL 599  Anopheles gambiae str. PEST
Q24492        575 QSVAPInhkeyNKHL 589  fruit fly
Q65XV7        730 VKVEKLdpskeSNVL 744  Japanese rice
F4JSG3        649 VKVDKLnysadTRTM 663  thale cress
Q9SKI4        620 VKVDKVnytseSKYM 634  thale cress
Q4N547        417 TNIEEVdyakeAESL 431  Theileria parva
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