3ZVM


Conserved Protein Domain Family
PNK3P

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pfam08645: PNK3P 
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Polynucleotide kinase 3 phosphatase
Polynucleotide kinase 3 phosphatases play a role in the repair of single breaks in DNA induced by DNA-damaging agents such as gamma radiation and camptothecin.
Statistics
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PSSM-Id: 370030
View PSSM: pfam08645
Aligned: 25 rows
Threshold Bit Score: 150.102
Threshold Setting Gi: 74608223
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3ZVM_A  59 KVAAFDLDGTLITTRS-GKVFPT-S----------PSDWRILYPE------IPKKLQEL-AAEG-----------YKLVI 108
O13911  69 KFIAFDLDGTLIKTKS-GRVFSK-D----------AADWTWWHPS------VVPKLKAL-YQDN-----------YSLVI 118 Schizosaccharomyces p...
Q8SV48  36 KLIMFDLDLTLICASS-NET---------------SHNWRYLFRE------VPAKIKEL-DKQG-----------YLIGI 81  Encephalitozoon cuniculi
Q5B129  79 KIAAFDFDSTLVATAS-GNTFPR-D----------SADWKWWRQN------VPSRLQKL-NADG-----------YHVVI 128 Aspergillus nidulans
Q7S497  87 KIAAFDLDSTLITSAS-GKKHSH-D----------AADWKWWHHS------VPDRLRKLyNEEG-----------YQVII 137 Neurospora crassa
Q4N9M3  45 SFAIYDMDNTLMITPSyFVEELKkGvqiqiskpliPNDFVLFAPN------VKEKLHYE-LNQG-----------RGILI 106 Theileria parva
Q6C478  86 PVAAFDLDSTITLTKS-GMPWPR-N----------GSDWKWFSDR------VVESLQAMhKTEDrkgsfpvphkpYIVVI 147 Yarrowia lipolytica
Q6BWY7 111 KIAAFDLDGTLVDTKT-GLKFAR-G----------ASDWRWWTSKdsknlnVMDKLKKL-VTDK-----------YIIVI 166 Debaryomyces hansenii
Q6CPX8  27 KVISFDLDHTVIKPVK-GRFSRT------------SDDWIFMKYGkt---eVLAKLSAQmKETPd----------FHIVF 80  Kluyveromyces lactis
Q03796  30 NVYAFDLDHTIIKPKSpNISFSR-S----------ASDWQFINFNsk--ksTLDYLCNIiDNDPt----------AVIVI 86  Saccharomyces cerevis...
3ZVM_A 109 FTNQMGIGR------------------GKLPAEVFKGKVEAVLEKL----GVP-----FQVLVATH-A------------ 148
O13911 119 FSNQNGIPR------------------KPSAGHTFQMKIRAIFESL----DLP-----IVLYAAIL-K------------ 158 Schizosaccharomyces p...
Q8SV48  82 ASNQSQLLR-------------------LNSLEMFIEKICSILTDL----DVP-----IVFLAALK-K------------ 120 Encephalitozoon cuniculi
Q5B129 129 FTNQGKISLkkdk-----------kgnVSSYFNKFKERVSAVMKQL----NIP-----LSVYAATE-H------------ 175 Aspergillus nidulans
Q7S497 138 FTNQGGLTLhaspssssssskpktpkaQLDRVPQFKQKCSAVLSQL----DIP-----TTLYAATG-K------------ 195 Neurospora crassa
Q4N9M3 107 ISNQRGMLE------------------NIPSAYLILERIELLLREL----DVP-----LYILLATD-H------------ 146 Theileria parva
Q6C478 148 ITNQGSLVPk----------------eGNKRYAHFVERIDSVTDFI----DIP-----VLVYAASKlEqkrgapkva--- 199 Yarrowia lipolytica
Q6BWY7 167 FSNQGGVVAt----------------kTSKSYLAFTGRVNNVLKEL----NTEkevpgVLVYASPK-Kpssknqki---- 221 Debaryomyces hansenii
Q6CPX8  81 FSNQGGVVSep---------------rTSKSCVKHVDKICKVLKYIs--eNDSqlcdrIWIYCATK-Kpaslfggskaas 142 Kluyveromyces lactis
Q03796  87 FSNQGGVITvp---------------rTSKSCTKYTNKILLFLKAIkndeRGEtlshrLWLYAAPK-Rpktfaanhski- 149 Saccharomyces cerevis...
3ZVM_A 149 ------------------------------G-----LNRKPVSGMWDHLQEQANEg----iPISVEDS---VFVGDAAGR 186
O13911 159 ------------------------------D-----KFRKPLTGMWNSFLKDVNR------SIDLSFI---KYVGDAAGR 194 Schizosaccharomyces p...
Q8SV48 121 ------------------------------N-----EYRKPSIGMYEYMCRKYIDe----cKITRK-----VYVGDAVNS 156 Encephalitozoon cuniculi
Q5B129 176 ------------------------------D-----EYRKPRAGMWKEFLDDYDFdv---tGIDSSQS---IFVGDAAGR 214 Aspergillus nidulans
Q7S497 196 ------------------------------D-----IYRKPRPGMWLEMKADYNLfn--ddDIDLENS---IFVGDAGGR 235 Neurospora crassa
Q4N9M3 147 ------------------------------D-----IYRKPAPGMLLFFERNLNGg----lPVDRDNS---FFVGDAAGR 184 Theileria parva
Q6C478 200 ---------------------tkseqdkdpN-----AFRKPGNGLWRRMTADLEKmh---mKVNTKDS---FYVGDAAGR 247 Yarrowia lipolytica
Q6BWY7 222 ----------------------avssdedhA-----IMRKPNIGMWNELAKYFEDqg---yTIDTNNS---FFVGDAAGR 268 Debaryomyces hansenii
Q6CPX8 143 tahankvvkniisgqkkringtmvtpemfdN------VRKPNRGLFDEFLKDSDEqs---dSIELL-----FYCGDAAGR 208 Kluyveromyces lactis
Q03796 150 -------------------tfaslgesynnDpnifeKVRKPMTGMVEFFKRDLESayrvseQISPIKLnwiYYCGDAAGR 210 Saccharomyces cerevis...
3ZVM_A 187 lanwa-------------------------------------------------pgrkKKDFSCADRLFALNVGLPFATP 217
O13911 195 ----------------------------------------------------------PGDHNSTDLKFAENIGIKFETP 216 Schizosaccharomyces p...
Q8SV48 157 sl-------------------------------------------------------gPGHTNSCDIKFAYNAGMEFKHP 181 Encephalitozoon cuniculi
Q5B129 215 ----------------------------------------------------------PGDHSAADRGFAANANMVFKTP 236 Aspergillus nidulans
Q7S497 236 qselppnsn-----------------------------------------grikatatPKDFSCSDRNLAHNVGIQYQTP 274 Neurospora crassa
Q4N9M3 185 rldykssslmmrnilsvlkstdystrryynvdengtivyinpyeiikrltiskmknrfSKDFSDCDFKFAINNSLTFLTP 264 Theileria parva
Q6C478 248 ----------------------------------------------------------PGDFAASDKAFAENVGIQFFTP 269 Yarrowia lipolytica
Q6BWY7 269 ----------------------------------------------------------SNDFLDSDKMFARNADLQFKIP 290 Debaryomyces hansenii
Q6CPX8 209 ----------------------------------------------------------PNDFSDSDKEFAKILGVPFKVP 230 Kluyveromyces lactis
Q03796 211 ----------------------------------------------------------KKDFSDSDIKFAENLHVEFKYP 232 Saccharomyces cerevis...
3ZVM_A 218 EEFF 221
O13911 217 EQFF 220 Schizosaccharomyces pombe 972h-
Q8SV48 182 VEFF 185 Encephalitozoon cuniculi
Q5B129 237 EEFF 240 Aspergillus nidulans
Q7S497 275 EEFF 278 Neurospora crassa
Q4N9M3 265 DEYF 268 Theileria parva
Q6C478 270 EEFF 273 Yarrowia lipolytica
Q6BWY7 291 EEIF 294 Debaryomyces hansenii
Q6CPX8 231 EEYF 234 Kluyveromyces lactis
Q03796 233 EEIF 236 Saccharomyces cerevisiae S288C
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