Conserved Protein Domain Family
SPO22

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pfam08631: SPO22 
Meiosis protein SPO22/ZIP4 like
SPO22/ZIP4 in yeast is a meiosis specific protein involved in sporulation. It has been shown to regulate crossover distribution by promoting synaptonemal complex formation.
Statistics
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PSSM-Id: 400797
View PSSM: pfam08631
Aligned: 79 rows
Threshold Bit Score: 85.4226
Threshold Setting Gi: 1572694615
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_004182645 199 LTIRNGNFETAKLYESQtdIPNNIDKLdPPLLLELCQIIYNSTVDLKelksvkctkpgHITQQFTDSdhlevikfiiYFL 278  Tetrapisispora...
XP_023814829  67 SAIAQGNNQEAIVFIER--CKDILLRL-PNETAYLSVVCYNFGIEAY-----------NLTKFEDSA----------FWL 122  Japanese medaka
3_pfamImport   1 SAVAQRDFQRAVMCVQR--CKDLLPRL-PRVPGYLSILCYNFGVDAY-----------YQKKFEECS----------HWL 56  
Q8IYF3       190 SAVAQGDFQRASMCVLQ--CKDMLMRL-PQMTSSLHHLCYNFGVETQ-----------KNNKYEESS----------FWL 245  human
XP_013220493 175 SAVAQGDFQRASTCALR--CKDMLMRL-PKMTGYLHVLCYNFGVETH-----------KHNKYQESS----------FWL 230  thirteen-lined...
EDL95920     176 SAVAQGDFKKASICVLR--CKDMLIRI-PEMTKYLHVLCYNFGVESS-----------KQNKYRESS----------FWL 231  Norway rat
Q14AT2       176 SAVAQGDFKKASMCVLR--CKDMLMRL-PNMTKYLHVLCYNLGIEAS-----------KRNKYKESS----------FWL 231  house mouse
ELK15653     175 SAVAQDDFPRASSCILR--CKDMLIRL-PKMTGYLHILCYNFGVETY-----------IQSKYEESA----------FWL 230  black flying fox
XP_014960418 175 AAVAEGDFQRASSCILR--CKDMLMRL-PQMAYYLHTVCYNLGIQIY-----------KENKYEESC----------FWL 230  sheep
XP_031158809  67 SALSQGNNHEAVVYMQR--CKDMLLRL-PKDTAYLSLMCYNFGIDTY-----------NLRKFEDSA----------FWL 122  pike-perch
XP_004182645 279 KKALEYLSldvkGLKGNlEYSNIRYNILLFLTDSFINfyEQLDSNIEDCQFYLNMLQNEYPkntEPFQLAIKLCKKKVSQ 358  Tetrapisispora...
XP_023814829 123 SQSYDIGK----ANMKYgPGSEALAKVLRLLATCYLE--WDCEKFQEKALNTVSLANKECV---TPFGLYLKIRILLRCR 193  Japanese medaka
3_pfamImport  57 SQSYDIGN----LNKNTpTGQDMQAKVLRLLANTYLD--WDWPWYQDKALKTLNLARVSLL---SPGLSFLISKITG--- 124 
Q8IYF3       246 SQSYDIGK----MDKKS-TGPEMLAKVLRLLATNYLD--WDDTKYYDKALNAVNLANKEHL---SSPGLFLKMKILLKGE 315  human
XP_013220493 231 SQSYDIGK----MDMNS-VGPEMLAKVLRLLATAYLD--WDDREYYEKALSAIILANKAHL---NPAGLFLKMRILLKGE 300  thirteen-lined...
EDL95920     232 SQSYDIGK----MGKDS-VEPEMLAKGLRLLATIYLN--CDDEAYYNKALIAVIVANKEHL---DPAGLFLKMRILIKGK 301  Norway rat
Q14AT2       232 GQSYEIGK----MDRRS-VEPQMLAKTLRLLATIYLN--CGGEAYYTKAFIAILIANKEHL---HPAGLFLKMRILMKGN 301  house mouse
ELK15653     231 SQSYDIGK----MEKSS-VDPEMLAKVLRLLATTYLD--WNDGDYY-KALSTVDLANKEHL---HPAGLHLKMKILLASE 299  black flying fox
XP_014960418 231 SQSYDIGR----TDRNS-VEPEMLAKVLRLLATAYLD--WDSSEYYDKALNIINLANKEEL---HPVGLFLKVKILLKNE 300  sheep
XP_031158809 123 SQSYEIGK----MNVKYaPGSEVQAKVLRLLATVYLE--WDCQRFQEKALNAVSLANKECV---SASGLYLKIRILLRCG 193  pike-perch
XP_004182645 359 NQEVNIKEILMGLITsvdIYIHLDTILGCISDFA-------------ELSTSDAVIILDYLLNnkvDfDSNSDiAEKIIL 425  Tetrapisispora...
XP_023814829 194 APDSPVRAGLNEMLe---SKVSLDMCLNTVRLLMs------------ENREVLAFEYLKTVCQ---HfESSPS-LGTALV 254  Japanese medaka
3_pfamImport 125 -----LDTFAWHMMD-----------VDLLHLFMpycfpdfpavfvpKARDSVGFDFLKTVCD---RfESSAD-VGKGFL 184 
Q8IYF3       316 TSNEELLEAVMEILh---LDMPLDFCLNIAKLLMd------------HERESVGFHFLTIIHE---RfKSSEN-IGKVLI 376  human
XP_013220493 301 TPNEELLEAVMEILh---FDMPLDFCLNIVKLLMd------------HERESVGFYFLKTICE---HfKSSEN-IGKAVL 361  thirteen-lined...
EDL95920     302 AFNEELLEAAKEVLy---LAMPLEFCLSIIQFLId------------NKRDSVGFCFLKIIAD---HfKLPEH-RKRILL 362  Norway rat
Q14AT2       302 SCNEELLEAAKEILy---LAMPLEFYLSIIQFLId------------NKRESVGFRFLRIISD---NfKSPED-RKRILL 362  house mouse
ELK15653     300 TVNEELFGAGMEILh---LNMSLDFCLHIAKQLId------------HGRDSVGFTFMELICE---HfKSSEN-IGKALV 360  black flying fox
XP_014960418 301 MANQELFQTLMEILh---FGMSLNFCLNIVKLLVd------------HERGSIGFYFLKIICE---HfQSSED-TSKAQL 361  sheep
XP_031158809 194 AADDHIRAGLNEMLe---SKVYLEVCLSTVKLLMs------------EDREVLAFEYLKRVCQ---HfESSPD-LGTALV 254  pike-perch
XP_004182645 426 SRYYLTVQSKTLTIqeIISSIIKFSELikRLIVHNFSKHIAASIITLLWNAGKKFEKEEMFNESVEFYKLCL 497  Tetrapisispora blattae...
XP_023814829 255 LHIELLLQRGKVLL--SRQKIEDVITG--HYTGKQLAPEALTSLHIILWDQASKHYEDDNYSEALQWYDYSL 322  Japanese medaka
3_pfamImport 185 LHVKLLLQRKEDQL--AKKKVEDILTA--HHAGKELPPQILSWLHTILWDRAAQNFEAQNYFEALQWYNYSL 252 
Q8IYF3       377 LHTDMLLQRKEELL--AKEKIEEIFLA--HQTGRQLTAESMNWLHNILWRQAASSFEVQNYTDALQWYYYSL 444  human
XP_013220493 362 FHIDMLLQRKEELL--AKEKIEEIIVG--HQTGSQLTTELVGWLQNILWNKAARSFEVQNYADALQWYYYSL 429  thirteen-lined ground ...
EDL95920     363 FYIDMLLQVDQDVI--AEEKIKEILID--HQTRSRLTRALVNWLHNILWGKATRCVKVQNYADALRWYSYSL 430  Norway rat
Q14AT2       363 FYIDTLLQKDQDMI--AEEKIKDVLKG--YQTRSRLSRDLVNWLHNILWGKASRSVKVQKYADALHWYSYSL 430  house mouse
ELK15653     361 FQADILLQRKEELL--AKEKIEEIMIG--HQTGRKLTTESIGYLHDILWEKAARNFEVKRYDDALQWYCYSL 428  black flying fox
XP_014960418 362 LHIDMLLQRKEEMF--AKEKVEEIIIG--HQTGKPLASELIGYFHSIIWKQAARSFQVHNFDNALHWYCYSL 429  sheep
XP_031158809 255 LHIELLLQRGKELL--GKQKIEDIITG--HYTGKQLTPQALTRLHVMLWDKASKHFEAKNYAEALQWYNYSL 322  pike-perch
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